Persistent carbene (section Triazol-5-ylidenes)
nitrogen atoms in triazol-5-ylidene, there are two possible isomers, namely 1,2,3-triazol-5-ylidenes and 1,2,4-triazol-5-ylidenes. The triazol-5-ylidenes based...
62 KB (6,933 words) - 11:59, 13 August 2024
3-Amino-1,2,4-triazole (3-AT) is a heterocyclic organic compound that consists of 1,2,4-triazole with an amino group as a substituent. 3-AT is a competitive...
7 KB (522 words) - 12:31, 20 September 2024
4-hydrazinobenzoic acid in the presence of base to give 4-(3,5-bis(2-hydroxyphenyl)-1,2,4-triazol-1-yl)benzoic acid (deferasirox). Deferasirox ranked second on the list...
11 KB (783 words) - 04:50, 7 September 2024
Trazodone (category 1,2,4-Triazol-3-ones)
21% Identifiers IUPAC name 2-{3-[4-(3-Chlorophenyl)piperazin-1-yl]propyl}[1,2,4]triazolo[4,3-a]pyridin-3(2H)-one CAS Number 19794-93-5 Y PubChem CID 5533...
115 KB (10,953 words) - 21:57, 10 October 2024
The triazol-5-ylidenes are a group of persistent carbenes which includes the 1,2,4-triazol-5-ylidene system and the 1,2,3-triazol-5-ylidene system. As...
22 KB (2,758 words) - 23:40, 9 December 2023
nonsteroidal benzyl triazole. It is also known as α,α,α',α'-tetramethyl-5-(1H-1,2,4-triazol-1-ylmethyl)-m-benzenediacetonitrile. Anastrozole is structurally related...
27 KB (2,332 words) - 04:27, 27 February 2024
Semicarbazide hydrochloride is condensed with formic acid to produce 1,2,4-triazol-3-one, which is nitrated with nitric acid to form nitrotriazolone. In...
7 KB (445 words) - 11:35, 6 September 2023
103°41'. dithallium diaquapentanitratocerate dihydrate. Bis{4-[(4H-1,2,4-triazol-4-yl)iminomethyl]pyridinium} diaquapentanitratocerate. (C8H8N5)2[Ce(NO3)5(H2O)2]...
25 KB (2,646 words) - 13:12, 8 October 2024
half-life 2 days Excretion Kidney Identifiers IUPAC name 4,4'-((1H-1,2,4-triazol-1-yl)methylene)dibenzonitrile CAS Number 112809-51-5 Y PubChem CID 3902...
20 KB (1,820 words) - 16:01, 16 October 2024
(2R,3R)-2-(2,4-Difluorophenyl)-3-(4-methylene-1-piperidinyl)-1-(1H-1,2,4-triazol-1-yl)-2-butanol CAS Number 164650-44-6 PubChem CID 489181 DrugBank DB09040...
10 KB (715 words) - 01:12, 2 September 2024
explosive formulation constituents: 2,4-Dinitroanisole (DNAN), 3-nitro-1,2,4-triazol-5-one (NTO), and nitroguanidine". Journal of Hazardous Materials. 280:...
35 KB (3,728 words) - 17:44, 30 September 2024
Kidney 61–88% Identifiers IUPAC name 2-(2,4-Difluorophenyl)-1,3-bis(1H-1,2,4-triazol-1-yl)propan-2-ol CAS Number 86386-73-4 Y PubChem CID 3365 DrugBank DB00196 Y...
31 KB (2,821 words) - 10:58, 27 May 2024
triazolobenzophenone Identifiers IUPAC name {2-[3-(Aminomethyl)-5-methyl-4H-1,2,4-triazol-4-yl]-5-chlorophenyl}(phenyl)methanone CAS Number 69505-70-0 Y PubChem...
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5-bis(trifluoromethyl)phenylethoxy)-3-(S)-(4-fluoro)phenyl-4- (3-oxo-1,2,4-triazol-5-yl)methylmorpholine, a potent, orally active, long-acting morpholine...
23 KB (2,208 words) - 05:59, 6 October 2024
(November 2005). "7-(1,1-Dimethylethyl)-6-(2-ethyl-2H-1,2,4-triazol-3-ylmethoxy)-3-(2-fluorophenyl)-1,2,4-triazolo[4,3-b]pyridazine: a functionally selective...
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1-(4-Chlorophenyl)- 4,4-dimethyl-3-(1H, 1,2,4-triazol-1-ylmethyl)pentan- 3-ol Other names (±)-1-(4-Chlorophenyl)-4,4-dimethyl-3-(1H, 1,2,4-triazol-1-ylmethyl)pentan-3-ol...
4 KB (198 words) - 17:45, 7 September 2024
4,4-Difluoro-N-[(1S)-3-{(1R,3s,5S)-3-[3-methyl-5-(propan-2-yl)-4H-1,2,4-triazol-4-yl]-8-azabicyclo[3.2.1]octan-8-yl}-1-phenylpropyl] cyclohexanecarboxamide...
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Excretion 82% urine; 12% feces Identifiers IUPAC name N,N-dimethyl-2-[5-(1H-1,2,4-triazol-1-ylmethyl)-1H-indol-3-yl]ethanamine CAS Number 145202-66-0 Y PubChem...
12 KB (672 words) - 14:57, 1 October 2024
(methylamino)acetyl]oxy}methyl)pyridin-2-yl]carbamoyl}oxy)ethyl]-1H-1,2,4-triazol-4-ium CAS Number 742049-41-8 sulfate: 946075-13-4 Y PubChem CID 6918606...
25 KB (1,437 words) - 21:56, 19 August 2024
humans at doses above 1 mg. "1,2,4-Triazolo(4,3-b)pyridazine, 7-cyclobutyl-3-(2,6-difluorophenyl)-6-((1-methyl-1H-1,2,4-triazol-5-yl)methoxy)-". "MRK-409"...
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is brominated and the resulting compound treated with the sodium salt of 1,2,4-triazole in a nucleophilic substitution reaction. The final reduction reaction...
23 KB (2,246 words) - 19:27, 9 August 2024
(4-isopropyl-1-piperazinyl)phenoxy]methyl}-1,3-dioxolan-2-yl]methyl}-1H-1,2,4-triazole. Terconazole has a melting point of 126.3 °C (259.34 °F). The molecular...
17 KB (1,964 words) - 00:17, 9 March 2024
Posaconazole (category 1,2,4-Triazol-3-ones)
1,2,4-triazol-1-ylmethyl)-3-furanyl]methoxy]phenyl]-1-piperazinyl]phenyl]-2-[(1S,2S)-1-ethyl-2- hydroxypropyl]-2,4-dihydro-3H-1,2,4-triazol-3-one...
14 KB (827 words) - 16:30, 19 September 2024
3-tert-butyl-7-(5-methylisoxazol-3-yl)-2-(1-methyl-1H-1,2,4-triazol-5-ylmethoxy)-pyrazolo[1,5-d]-[1,2,4]triazine (MRK-016), a GABAA receptor alpha5 subtype-selective...
3 KB (166 words) - 22:20, 3 December 2023
Itraconazole (category 1,2,4-Triazol-3-ones)
4S)-rel-2-(2,4-dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]-1-piperazinyl]phenyl]-Δ2-1,2,4-triazolin-5-one CAS Number 84625-61-6 Y...
26 KB (2,397 words) - 16:07, 20 May 2024
Identifiers IUPAC name (8S,9R)-5-Fluoro-8-(4-fluorophenyl)-9-(1-methyl-1H-1,2,4-triazol-5-yl)-2,7,8,9-tetrahydro-3H-pyrido[4,3,2-de]phthalazin-3-one CAS Number...
16 KB (1,230 words) - 04:49, 15 September 2024
ethoxy]-3-(4-fluorophenyl)morpholin-4-yl]methyl}-5-oxo- 2H-1,2,4-triazol-1-yl]phosphonic acid CAS Number 172673-20-0 Y 265121-04-8 (dimeglumine)...
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4]diazepin-2(3H)-one 21738192 Compound 6a 9.5 † 7-chloro-5-(3,5-dimethyl-4H-1,2,4-triazol-4-yl)-1,3-dihydro-2H-1,4-benzodiazepin-2-one JC-184 7-bromo-5-(2-thienyl)-1H-benzo[e]...
108 KB (3,088 words) - 21:34, 19 September 2024
Nefazodone (category 1,2,4-Triazol-3-ones)
1-(3-[4-(3-chlorophenyl)piperazin-1-yl]propyl)-3-ethyl-4-(2-phenoxyethyl)-1H-1,2,4-triazol-5(4H)-one CAS Number 83366-66-9 Y 82752-99-6 (hydrochloride) PubChem...
38 KB (2,970 words) - 08:04, 1 October 2024
7,10,15-tetramethyl-7-[(2R)-3-methylbutan-2-yl]-20-(5-pyridin-4-yl-1,2,4-triazol-1-yl)-17-oxapentacyclo[13.3.3.01,14.02,11.05,10]henicos-2-ene-6-carboxylic...
12 KB (710 words) - 08:51, 21 October 2023