• enzymology, a 1-pyrroline-5-carboxylate dehydrogenase (EC 1.2.1.88) is an enzyme that catalyzes the chemical reaction (S)-1-pyrroline-5-carboxylate + NAD+ +...
    3 KB (261 words) - 13:19, 19 December 2023
  • Thumbnail for 1-Pyrroline-5-carboxylic acid
    degradation, the enzyme proline dehydrogenase produces P5C from proline, and the enzyme 1-pyrroline-5-carboxylate dehydrogenase converts GSA to glutamate....
    6 KB (543 words) - 22:44, 18 October 2024
  • Thumbnail for Hyperprolinemia
    broken down properly by the enzymes proline oxidase or pyrroline-5-carboxylate dehydrogenase, causing a buildup of proline in the body. Mutations in...
    8 KB (784 words) - 17:55, 28 October 2024
  • Thumbnail for Aldehyde dehydrogenase 4 family, member A1
    Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial is an enzyme that in humans is encoded by the ALDH4A1 gene. This protein belongs to the aldehyde...
    5 KB (675 words) - 11:37, 15 November 2024
  • tremens Delusional disorder Delleman–Oorthuys syndrome Delta-1-pyrroline-5-carboxylate dehydrogenase deficiency Delta-sarcoglycanopathy Dementia Dementia, alcohol...
    13 KB (1,155 words) - 22:52, 28 April 2024
  • Thumbnail for Aldehyde dehydrogenase 18 family, member A1
    Delta-1-pyrroline-5-carboxylate synthetase (P5CS) is an enzyme that in humans is encoded by the ALDH18A1 gene. This gene is a member of the aldehyde dehydrogenase...
    14 KB (1,678 words) - 15:44, 27 September 2023
  • Thumbnail for Proline dehydrogenase
    (S)-1-pyrroline-5-carboxylate during proline catabolism. The end product of this reaction is then further oxidized in a (S)-1-pyrroline-5-carboxylate dehydrogenase...
    7 KB (771 words) - 00:41, 28 November 2023
  • 1-piperideine-2-carboxylate/1-pyrroline-2-carboxylate reductase (NADPH) EC 1.5.1.22: strombine dehydrogenase EC 1.5.1.23: tauropine dehydrogenase EC 1.5.1.24:...
    189 KB (24,607 words) - 12:36, 11 June 2024
  • reaction D-proline + acceptor ⇌ {\displaystyle \rightleftharpoons } 1-pyrroline-2-carboxylate + reduced acceptor This enzyme is a flavoprotein (FAD). Tani Y...
    2 KB (170 words) - 13:43, 26 August 2023
  • either spontaneously cyclize to form 1-pyrroline-5-carboxylic acid, which is reduced to proline by pyrroline-5-carboxylate reductase (using NADH or NADPH)...
    33 KB (3,142 words) - 17:38, 21 February 2024
  • either spontaneously cyclize to form 1-pyrroline-5-carboxylic acid, which is reduced to proline by pyrroline-5-carboxylate reductase (using NADH or NADPH)...
    23 KB (2,240 words) - 05:28, 11 November 2024
  • either spontaneously cyclize to form 1-pyrroline-5-carboxylic acid, which is reduced to proline by pyrroline-5-carboxylate reductase (using NADH or NADPH)...
    2 KB (251 words) - 20:44, 21 August 2024
  • Thumbnail for Imine reductase
    of IREDs. 3-Hydroxybutyrate dehydrogenase Opine dehydrogenase Pyrroline-2-carboxylate reductase Pyrroline-5-carboxylate reductase Mangas-Sanchez J, France...
    7 KB (760 words) - 17:08, 21 September 2024
  • spontaneously cyclizes to pyrroline-5-carboxylate. Pyrroline-5-carboxylate is further reduced by the enzyme pyrroline-5-carboxylate reductase (P5CR) to yield...
    61 KB (6,770 words) - 15:11, 20 August 2024
  • Thumbnail for PYCR1
    Pyrroline-5-carboxylate reductase 1, mitochondrial is an enzyme that in humans is encoded by the PYCR1 gene. This gene encodes an enzyme that catalyzes...
    6 KB (622 words) - 21:08, 13 October 2022
  • Thumbnail for Acetyl-CoA
    giving off 33.5 kJ/mol of energy. The oxidative conversion of pyruvate into acetyl-CoA is referred to as the pyruvate dehydrogenase reaction. It is...
    22 KB (2,097 words) - 03:05, 2 November 2024
  • Thumbnail for Oxaloacetic acid
    L-malate, catalyzed by malate dehydrogenase, in the citric acid cycle. Malate is also oxidized by succinate dehydrogenase in a slow reaction with the initial...
    12 KB (1,159 words) - 14:05, 16 November 2024
  • Thumbnail for Nicotinamide adenine dinucleotide
    K (2005). "Crystal structures of Delta1-piperideine-2-carboxylate/Delta1-pyrroline-2-carboxylate reductase belonging to a new family of NAD(P)H-dependent...
    79 KB (9,020 words) - 21:04, 28 October 2024
  • Thumbnail for Cutis laxa
    Inheritance in Man (OMIM): Fibulin 5; FBLN5 - 604580 Online Mendelian Inheritance in Man (OMIM): Pyrroline-5-Carboxylate Reductase 1; PYCR1 - 179035 Online Mendelian...
    12 KB (1,176 words) - 12:51, 2 September 2024
  • Thumbnail for 2-Oxoadipic acid
    conjugate base and carboxylate is 2-oxoadipate or α-ketoadipate, which is the biochemically relevant form. Homoisocitrate dehydrogenase 2-oxoadipate - Compound...
    3 KB (105 words) - 21:24, 5 March 2024
  • Thumbnail for NOXRED1
    chromosome 14, at 14q24.3. NOXRED1 is predicted to be involved in pyrroline-5-carboxylate reductase activity as part of the L-proline biosynthetic pathway...
    18 KB (1,544 words) - 09:50, 11 August 2024
  • Thumbnail for Glutamic acid
    The change in protonation state occurs at pH 4.07. This form with both carboxylates lacking protons is dominant in the physiological pH range (7.35–7.45)...
    35 KB (3,237 words) - 17:07, 11 September 2024
  • deaminase EC 3.5.4.19: phosphoribosyl-AMP cyclohydrolase EC 3.5.4.20: pyrithiamine deaminase EC 3.5.4.21: creatinine deaminase EC 3.5.4.22: 1-pyrroline-4-hydroxy-2-carboxylate...
    119 KB (15,555 words) - 06:24, 19 September 2024
  • cycle, where it is synthesized from α-ketoglutarate by α-ketoglutarate dehydrogenase through decarboxylation. During the process, coenzyme A is added. With...
    5 KB (308 words) - 15:24, 6 May 2024
  • Thumbnail for Α-Ketoisocaproic acid
    also known as 4-methyl-2-oxovaleric acid, and its conjugate base and carboxylate, α-ketoisocaproate, are metabolic intermediates in the metabolic pathway...
    12 KB (1,573 words) - 20:04, 31 October 2024
  • oxidase MeSH D08.811.682.662.693 – 1-pyrroline-5-carboxylate dehydrogenase MeSH D08.811.682.662.695 – pyrroline carboxylate reductases MeSH D08.811.682.662...
    158 KB (15,232 words) - 06:41, 8 March 2024
  • Thumbnail for Glycine
    reacts with many reagents. These can be classified into N-centered and carboxylate-center reactions. Glycine is not essential to the human diet, as it is...
    40 KB (3,766 words) - 11:02, 30 October 2024
  • Thumbnail for 3-Phosphoglyceric acid
    3-Phosphoglyceric acid (category Carboxylate anions)
    glycolysis) and the subsequent catalysis by glyceraldehyde 3-phosphate dehydrogenase into G3P. G3P eventually reacts to form the sugars such as glucose or...
    13 KB (1,003 words) - 11:07, 14 January 2024
  • oxidation into agmatine-aldehyde, which is in turn converted by aldehyde dehydrogenase into guanidinobutyrate and secreted by the kidneys. Agmatine was found...
    18 KB (1,931 words) - 03:32, 28 August 2024
  • Thumbnail for Stress granule
    81 (5): 2165–2178. doi:10.1128/JVI.02287-06. PMC 1865933. PMID 17166910. Goodier JL, Zhang L, Vetter MR, Kazazian HH (September 2007). "LINE-1 ORF1 protein...
    183 KB (12,460 words) - 13:46, 23 September 2024