• In enzymology, a 4-coumarateCoA ligase (EC 6.2.1.12) is an enzyme that catalyzes the chemical reaction ATP + 4-coumarate + CoA ⇌ {\displaystyle \rightleftharpoons...
    3 KB (253 words) - 12:40, 26 August 2023
  • trans-cinnamate 4-monooxygenase to give 4-hydroxycinnamate (i.e, coumarate). Coumarate is condensed with coenzyme-A in the presence of 4-coumarate-CoA ligase: ATP...
    4 KB (160 words) - 19:56, 20 December 2023
  • Thumbnail for Cinnamaldehyde
    trans-cinnamic acid. In the second step, 4-coumarateCoA ligase (4CL) converts cinnamic acid to cinnamoyl-CoA by an acid–thiol ligation. 4CL uses ATP to...
    20 KB (1,852 words) - 14:49, 9 September 2024
  • Thumbnail for Hesperidin
    cinnamate 4-hydroxylase to afford (E)-4-coumarate, which is transformed into (E)-4-coumaroyl-CoA by 4-coumarate-CoA ligase. (E)-4-coumaroyl-CoA is then...
    15 KB (1,228 words) - 16:46, 20 September 2024
  • Thumbnail for Anthocyanin
    to naringenin by phenylalanine ammonialyase, cinnamate 4-hydroxylase, 4-coumarate CoA ligase, chalcone synthase, and chalcone isomerase. Then, the next...
    47 KB (4,595 words) - 15:04, 2 November 2024
  • Thumbnail for Gingerol
    acid (3) with use of cinnamate 4-hydroxylase (C4H). 4-coumarate:CoA ligase (4CL) is then used to get p-Coumaroyl-CoA (5). P-Coumaroyl shikimate transferase...
    25 KB (2,832 words) - 22:42, 24 December 2023
  • 2.1.10: Acid—CoA ligase (GDP-forming) EC 6.2.1.11: Biotin—CoA ligase EC 6.2.1.12: 4-coumarateCoA ligase EC 6.2.1.13: Acetate—CoA ligase (ADP-forming)...
    33 KB (3,650 words) - 18:48, 10 September 2024
  • Thumbnail for Xanthohumol
    oxidized by cinnamate-4-hydroxylase and loaded onto Coenzyme A (CoA) by 4-coumarate CoA ligase to yield 4-hydroxy-cinnamoyl CoA, the starter unit for...
    9 KB (833 words) - 10:44, 16 June 2024
  • Thumbnail for Rutin
    Cinnamic acid is catalyzed by cinnamic acid-4-hydroxylase (C4H) and 4-coumarate-CoA ligase (4CL) to form p-coumaroyl-CoA. Subsequently, chalcone synthase (CHS)...
    13 KB (1,077 words) - 23:11, 12 September 2024
  • carboxylic acid—CoA ligase (GDP-forming) EC 6.2.1.11: biotin—CoA ligase EC 6.2.1.12: 4-coumarateCoA ligase EC 6.2.1.13: acetate—CoA ligase (ADP-forming)...
    25 KB (2,811 words) - 23:21, 22 July 2023
  • (p-coumaric acid). 4-Coumarate-CoA ligase is the enzyme that transforms 4-coumarate (p-coumaric acid) into 4-coumaroyl-CoA. Cinnamyl-alcohol dehydrogenase...
    5 KB (573 words) - 20:40, 4 September 2024
  • Thumbnail for Flavones
    cinnamate 4-hydroxylase to yield p-Coumaric acid. Coenzyme A is attached to the carboxylate facilitated by 4-Coumarate-CoA ligase, forming (Coumaroyl-CoA). A...
    15 KB (976 words) - 12:18, 16 May 2024
  • Thumbnail for Apigenin
    (TAL) to arrive at p-coumarate. To complete the general phenylpropanoid pathway, 4-coumarate CoA ligase (4CL) substitutes coenzyme A (CoA) at the carboxy group...
    12 KB (1,048 words) - 22:47, 25 October 2024
  • Thumbnail for Eugenol
    converted to feruloyl-CoA by the enzyme 4-hydroxycinnamoyl-CoA ligase (4CL). Next, feruloyl-CoA is reduced to coniferaldehyde by cinnamoyl-CoA reductase (CCR)...
    25 KB (2,316 words) - 08:33, 22 November 2024
  • Thumbnail for Silibinin
    the production of coniferyl alcohol is carried out by 4-hydroxycinnamate CoA ligase, cinnamoyl CoA reductase, and cinnamyl alcohol dehydrogenase. For taxifolin...
    21 KB (2,233 words) - 08:08, 21 August 2024
  • incorporated into EC 2.4.1.186, glycogenin glucosyltransferase EC 2.4.1.113: α-1,4-glucan-protein synthase (ADP-forming) EC 2.4.1.114: 2-coumarate O-β-glucosyltransferase...
    215 KB (21,664 words) - 23:41, 8 May 2024
  • Thumbnail for Jane Shin
    J. J.; Douglas, C. J. (September 2001). "Identification of 4-coumarate:coenzyme A ligase (4CL) substrate recognition domains". The Plant Journal: For...
    19 KB (1,582 words) - 16:24, 15 November 2024