5α-Dihydroprogesterone (5α-DHP, allopregnanedione, or 5α-pregnane-3,20-dione) is an endogenous progestogen and neurosteroid that is synthesized from progesterone...
10 KB (909 words) - 23:12, 9 November 2023
5α-reductase: Cholestenone → 5α-Cholestanone Progesterone → 5α-Dihydroprogesterone 3α-Dihydroprogesterone → Allopregnanolone 3β-Dihydroprogesterone →...
37 KB (4,017 words) - 02:57, 2 November 2024
Allopregnanolone (redirect from 3α,5α-tetrahydroprogesterone)
progestogenic effects. (5α-dihydroprogesterone is reduced to produce allopregnanolone, and progesterone is reduced to produce 5α-dihydroprogesterone). In addition...
50 KB (4,782 words) - 13:47, 19 July 2024
Progesterone (category 5α-Reductase inhibitors)
Progesterone, through its neurosteroid active metabolites such as 5α-dihydroprogesterone and allopregnanolone, acts indirectly as a positive allosteric modulator...
123 KB (11,583 words) - 00:00, 6 November 2024
where androstenedione is converted into 5α-dihydrotestosterone (DHT) and testosterone (T) in male and into 5α-dihydroandrostenedione (DHA) in females...
19 KB (1,914 words) - 01:23, 11 November 2024
Androstenone (redirect from 5α-androst-16-en-4-one)
Androstenone (5α-androst-16-en-3-one) is a 16-androstene class steroidal pheromone. It is found in boar's saliva, celery cytoplasm,[citation needed] and...
12 KB (1,148 words) - 01:06, 4 April 2024
Δ5-Androstenediol Δ5-Androstenedione AA-861 Allopregnanediol Allopregnanedione (5α-dihydroprogesterone) Allopregnanolone (brexanolone) Alpha-Lipoic acid Ambrisentan AMI-193...
9 KB (673 words) - 18:57, 5 November 2024
(very weak), 20α-dihydroprogesterone (20α-DHP), 20β-dihydroprogesterone (20β-DHP), 5α-dihydroprogesterone (5α-DHP), 5β-dihydroprogesterone (5β-DHP) (very...
16 KB (1,567 words) - 01:04, 8 October 2024
Isopregnanolone (redirect from 3β-hydoxy-5α-pregnan-20-one)
body by the actions of the enzymes 5α-reductase and 3β-hydroxysteroid dehydrogenase (with 5α-dihydroprogesterone as the intermediate in this two-step...
7 KB (560 words) - 15:56, 5 February 2024
progesterone. Levels of 5α-DHP have been quantified. 20β-Dihydroprogesterone 17α-Hydroxyprogesterone 16α-Hydroxyprogesterone 5α-Dihydroprogesterone 11-Deoxycorticosterone...
10 KB (879 words) - 07:57, 18 August 2023
reduction, 5α-reductase isoforms I and II reduce progesterone to 5α-dihydroprogesterone (5α-DHP) and deoxycorticosterone to dihydrodeoxycorticosterone (DHDOC)...
31 KB (3,433 words) - 22:05, 21 October 2024
Dihydrotestosterone (redirect from 5α-Dihydrotestosterone)
5α-pregnan-17α-ol-3,20-dione → 5α-pregnane-3α,17α-diol-20-one → androsterone → 5α-androstane-3α,17β-diol → DHT. progesterone → 5α-dihydroprogesterone...
67 KB (6,840 words) - 00:18, 4 November 2024
Dihydroprogesterone may refer to: 5α-Dihydroprogesterone 5β-Dihydroprogesterone 20α-Dihydroprogesterone (20α-hydroxyprogesterone) 20β-Dihydroprogesterone...
618 bytes (69 words) - 01:36, 17 October 2018
uterine contractility through activation of this receptor. Unlike 5α-dihydroprogesterone, 5β-DHP possesses only very weak affinity for the progesterone receptor...
10 KB (908 words) - 11:09, 3 December 2023
Levels of 5α-DHP have been quantified. 3β-Dihydroprogesterone 5α-Dihydroprogesterone 5β-Dihydroprogesterone Pregnanolone Pregnenolone Neurosteroids and...
4 KB (304 words) - 01:22, 27 April 2023
studies showing that it is metabolized by aromatase or 5α-reductase into estrogenic compounds, or into 5α-reduced androgenic compounds, respectively. The potency...
23 KB (1,906 words) - 08:25, 12 July 2024
Androstenol (redirect from 5α-Androst-16-en-3α-ol)
Androstenol, also known as 5α-androst-16-en-3α-ol (shortened to 3α,5α-androstenol or 3α-androstenol), is a 16-androstene class steroidal pheromone and...
8 KB (693 words) - 12:26, 20 March 2024
androgen receptor, or can be reduced to 5α-dihydrotestosterone (5α-DHT) by the cytoplasmic enzyme 5α-reductase. 5α-DHT binds to the same androgen receptor...
149 KB (15,703 words) - 16:01, 5 November 2024
Androgen action in target tissues often involves conversion of testosterone to 5α-dihydrotestosterone (DHT). At the time of puberty, androgen levels increase...
29 KB (3,167 words) - 11:40, 22 November 2024
approximately 50% into 5α-dihydroprogesterone in the corpus luteum, 35% into 3β-dihydroprogesterone in the liver, and 10% into 20α-dihydroprogesterone. Metabolites...
175 KB (18,968 words) - 15:19, 3 July 2024
groups, respectively. For example, 5α-pregnane-3α,17α-diol-20-one has a hydrogen atom at the 5α position (hence the "5α-" prefix), two hydroxy groups (-OH)...
83 KB (8,523 words) - 03:36, 18 November 2024
Agonists Progesterone derivatives: 3β-Dihydroprogesterone 5α-Dihydroprogesterone 6α-Methylprogesterone 9α-Bromo-11-ketoprogesterone 11-Dehydroprogesterone...
34 KB (3,346 words) - 19:39, 31 October 2024
Agonists Progesterone derivatives: 3β-Dihydroprogesterone 5α-Dihydroprogesterone 6α-Methylprogesterone 9α-Bromo-11-ketoprogesterone 11-Dehydroprogesterone...
16 KB (1,220 words) - 14:16, 5 September 2024
(androst-4-en-17β-ol-3-one). DHEA is the 5-dehydro analogue of epiandrosterone (5α-androstan-3β-ol-17-one) and is also known as 5-dehydroepiandrosterone or as...
42 KB (3,937 words) - 11:44, 15 November 2024
Cholesterol Pregnanes: 3α-Dihydroprogesterone 3β-Dihydroprogesterone 5α-Dihydrocorticosterone 5α-Dihydroprogesterone 5β-Dihydroprogesterone Allopregnanolone Corticosterone...
32 KB (3,379 words) - 15:04, 21 November 2024
progestogenic activity, whereas 3α-DHP was not assessed. 5α-Dihydroprogesterone 5β-Dihydroprogesterone 3β-Androstanediol Pregnenolone Progesterone 3-acetyl...
4 KB (334 words) - 01:24, 27 April 2023
BANTooltip British Approved Name. 11α-Hydroxyprogesterone 5α-Dihydroprogesterone 20-Dihydroprogesterone 11-Deoxycorticosterone 11-Deoxycortisol 17α-Methylprogesterone...
14 KB (1,126 words) - 10:08, 7 July 2024
antiandrogen spironolactone, the progestin medroxyprogesterone acetate, and the 5α-reductase inhibitors finasteride and dutasteride. The steroidal antiandrogen...
139 KB (13,937 words) - 14:55, 12 November 2024
Agonists Progesterone derivatives: 3β-Dihydroprogesterone 5α-Dihydroprogesterone 6α-Methylprogesterone 9α-Bromo-11-ketoprogesterone 11-Dehydroprogesterone...
125 KB (11,569 words) - 02:29, 11 September 2024
testosterone and dihydrotestosterone (DHT). Trestolone is not a substrate for 5α-reductase and hence is not potentiated or inactivated in so-called "androgenic"...
21 KB (1,843 words) - 05:55, 16 August 2024