5-HT receptors, 5-hydroxytryptamine receptors, or serotonin receptors, are a group of G protein-coupled receptor and ligand-gated ion channels found in...
65 KB (5,263 words) - 10:40, 12 August 2024
receptor (or 5-HT1A receptor) is a subtype of serotonin receptors, or 5-HT receptors, that binds serotonin, also known as 5-HT, a neurotransmitter. 5-HT1A...
58 KB (6,188 words) - 15:33, 22 September 2024
The 5-HT2C receptor is a subtype of the 5-HT2 receptor that binds the endogenous neurotransmitter serotonin (5-hydroxytryptamine, 5-HT). Like all 5-HT2...
51 KB (6,107 words) - 06:54, 14 November 2024
is encoded by the HTR1B gene. The 5-HT1B receptor is a 5-HT receptor subtype. 5-HT1B receptors are widely distributed throughout the central nervous system...
17 KB (1,984 words) - 08:01, 27 October 2024
The 5-HT2A receptor is a subtype of the 5-HT2 receptor that belongs to the serotonin receptor family and is a G protein-coupled receptor (GPCR). The 5-HT2A...
91 KB (9,997 words) - 04:00, 14 November 2024
functionally from all other 5-HT receptors (5-hydroxytryptamine, or serotonin receptors) which are G protein-coupled receptors. This ion channel is cation-selective...
22 KB (2,395 words) - 18:29, 18 July 2024
of the 5-HT2 receptor family that binds the neurotransmitter serotonin (5-hydroxytryptamine, 5-HT). Like all 5-HT2 receptors, the 5-HT2B receptor is Gq/G11-protein...
33 KB (3,546 words) - 21:55, 10 November 2024
The 5-HT2 receptors are a subfamily of 5-HT receptors that bind the endogenous neurotransmitter serotonin (5-hydroxytryptamine, 5-HT). The 5-HT2 subfamily...
2 KB (166 words) - 00:47, 13 May 2022
serotonin receptor antagonist, is a drug used to inhibit the action of serotonin and serotonergic drugs at serotonin (5-HT) receptors. Antagonists of the 5-HT2A...
5 KB (503 words) - 03:53, 9 October 2024
conditions, and 5-HT receptors are also associated with neural changes. The gene described in this record is a member of 5-hydroxytryptamine receptor family and...
15 KB (1,674 words) - 17:31, 10 November 2024
activated by the neurotransmitter serotonin (5-hydroxytryptamine, 5-HT). The 5-HT7 receptor is coupled to Gs (stimulates the production of the intracellular...
25 KB (2,992 words) - 06:56, 16 November 2024
serotonin (5-hydroxytryptamine; 5-HT), a neurotransmitter and hormone and the endogenous ligand of the serotonin receptors. Serotonergic psychedelics such...
16 KB (1,662 words) - 21:10, 6 November 2024
5-hydroxytryptamine (serotonin) receptor 1D, also known as HTR1D, is a 5-HT receptor, but also denotes the human gene encoding it. 5-HT1D acts on the central...
11 KB (1,238 words) - 09:14, 27 October 2024
The 5-HT1 receptors are a subfamily of the 5-HT serotonin receptors that bind to the endogenous neurotransmitter serotonin (also known as 5-hydroxytryptamine...
5 KB (472 words) - 12:54, 25 December 2023
Chamomile (ethanol extract) 5-HT receptor 5-HT1 receptor 5-HT2 receptor 5-HT3 receptor 5-HT5 receptor 5-HT6 receptor 5-HT7 receptor GRCh38: Ensembl release...
18 KB (2,074 words) - 04:01, 28 October 2024
(5-Hydroxy-3-(1-methylpiperidin-4-yl)-1H-indole) - mixed 5-HT1e/1F agonist None as yet. 5-HT1 receptor 5-HT receptor GRCh38: Ensembl release 89: ENSG00000168830 –...
9 KB (1,202 words) - 03:08, 31 October 2024
relation to Parkinson's disease. 5-HT receptor 5-HT1 receptor 5-HT2 receptor 5-HT3 receptor 5-HT4 receptor 5-HT5 receptor GRCh38: Ensembl release 89: ENSG00000158748...
29 KB (3,308 words) - 15:33, 22 September 2024
- mixed 5-HT1B/1D/1F agonist Lasmiditan - selective 5-HT1F agonist, a first-in-class ditan molecule MLS000756415 5-HT1 receptor 5-HT receptor GRCh38:...
9 KB (1,053 words) - 15:17, 26 November 2023
number of 5-HT receptor subtypes were involved in the IBS symptoms, including 5-HT3, 5-HT4, and 5-HT7 receptors. High levels of 5-HT7 receptor-expressing...
126 KB (13,796 words) - 03:35, 21 November 2024
The 5-HT3 antagonists, informally known as "setrons", are a class of drugs that act as receptor antagonists at the 5-HT3 receptor, a subtype of serotonin...
43 KB (4,628 words) - 10:52, 21 February 2024
5-HT5B receptor is a 5-HT receptor protein and the gene which encodes it. The protein is found in rodents, but not in humans, because stop codons in the...
3 KB (348 words) - 07:25, 24 December 2023
Discovery and development of triptans (section Relevant structural features of triptans and binding to the receptor)
for 5-HT to be used as a drug, scientists started research on the receptors of 5-HT in order to discover and develop a more specific agonist for 5-HT receptors...
33 KB (2,832 words) - 20:46, 10 August 2024
Triptan (category 5-HT1D agonists)
are selective agents for 5-HT1B and 5-HT1D and have low or even no affinity for other types of 5-HT receptors. 5-HT receptors are classified into seven...
37 KB (3,655 words) - 21:58, 21 October 2024
Α-Methylserotonin (redirect from Α-methyl-5-HT)
closely related to the neurotransmitter serotonin (5-HT). It acts as a non-selective serotonin receptor agonist and has been used extensively in scientific...
10 KB (836 words) - 08:21, 11 November 2024
Production of 5-HTP is the rate-limiting step in 5-HT (serotonin) synthesis. 5-HTP is normally rapidly converted to 5-HT by amino acid decarboxylase. 5-HTP is...
14 KB (1,268 words) - 07:33, 8 October 2024
pigment-like receptor opsin) InterPro: IPR001793 5-Hydroxytryptamine (5-HT) receptor InterPro: IPR002231 5-HT2A (HTR2A, 5H2A) 5-HT2B (HTR2B, 5H2B) 5-HT2C (HTR2C...
25 KB (2,172 words) - 01:01, 29 November 2023
2-Methyl-5-hydroxytryptamine (2-Methylserotonin, 2-Methyl-5-HT) is a tryptamine derivative closely related to the neurotransmitter serotonin which acts...
3 KB (188 words) - 16:26, 21 October 2024
"Hyperglycemia induced by the 5-HT receptor agonist, 5-methoxytryptamine, in rats: involvement of the peripheral 5-HT2A receptor". Eur J Pharmacol. 323 (2–3):...
7 KB (630 words) - 06:11, 14 November 2024
both ENS neurons and smooth muscle. 5-HT also activates a neural secretory response, whereby binding at 5-HT1P receptors on myenteric neurons triggers a signalling...
16 KB (1,998 words) - 11:39, 13 November 2024