7-Methylguanosine (m7G) is a modified purine nucleoside. It is a methylated version of guanosine and when found in human urine, it may be a biomarker...
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7-Methylguanine is a modified purine nucleobase. It is a methylated version of guanine. The 7-methylguanine nucleoside is called 7-methylguanosine. However...
5 KB (342 words) - 00:05, 3 October 2021
M7G(5')pppN diphosphatase (redirect from 7-methylguanosine-5'-triphospho-5'-polynucleotide 7-methylguanosine-5'-phosphohydrolase)
chemical reaction 7-methylguanosine 5'-triphospho-5'-polynucleotide + H2O ⇌ {\displaystyle \rightleftharpoons } 7-methylguanosine 5'-phosphate + polynucleotide...
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nucleosides pseudouridine (Ψ), dihydrouridine (D), inosine (I), and 7-methylguanosine (m7G). Hypoxanthine and xanthine are two of the many bases created...
15 KB (1,434 words) - 14:39, 12 August 2024
methyltransferase transfers a methyl group to the guanosine cap to yield 7-methylguanosine cap that is attached to the 5' end of the transcript. These three...
14 KB (1,568 words) - 16:39, 7 November 2023
Polyadenylation of the 3' end RNA Splicing of the introns During capping, a 7-methylguanosine residue is attached to the 5'-terminal end of the primary transcripts...
6 KB (596 words) - 20:39, 4 September 2024
has been used as demethylating reagent. For example, treatment with 7-methylguanosine gives guanosine. Other N-methylated nucleosides in tRNA are not demethylated...
8 KB (700 words) - 14:59, 26 June 2024
pseudouridine (Ψ), dihydrouridine (D), inosine (I), ribothymidine (rT) and 7-methylguanosine (m7G). Hypoxanthine and xanthine are two of the many bases created...
22 KB (2,409 words) - 23:07, 24 August 2024
joined.[citation needed] A 5' cap (also termed an RNA cap, an RNA 7-methylguanosine cap, or an RNA m7G cap) is a modified guanine nucleotide that has...
49 KB (5,922 words) - 14:24, 18 August 2024
7-methylguanosine cap. Therefore, the nudix domain is what allows Dcp2 to remove the 5' cap, which results in the creation 7mGDP, a 7-methylguanosine...
18 KB (2,311 words) - 14:26, 10 August 2024
eukaryotes, a pre-mRNA's 5' end is modified by the addition of a 7-methylguanosine cap, also known as a 5' cap. The 5' capping modification is initiated...
21 KB (2,624 words) - 06:00, 3 September 2024
used by the cell. Capping of the pre-mRNA involves the addition of 7-methylguanosine (m7G) to the 5' end. To achieve this, the terminal 5' phosphate requires...
11 KB (1,432 words) - 23:35, 24 July 2024
7-methylguanosine 5'-phosphate + pp5'N(3'ppp5'N)n (2) 7-methylguanosine 5'-diphosphate + H2O ⇌ {\displaystyle \rightleftharpoons } 7-methylguanosine 5'-phosphate...
3 KB (316 words) - 14:49, 26 August 2023
recruited to the 5′ end of the mRNA. Eukaryotic mRNA is capped with a 7-methylguanosine (m7G) nucleotide which can help recruit the PIC to the mRNA and initiate...
30 KB (3,629 words) - 08:55, 7 July 2024
phosphate. However, in vitro-transcribed (ivT) long RNA containing a 7-methylguanosine cap (present in eukaryotic mRNA) is also highly immunogenic despite...
34 KB (4,151 words) - 09:53, 12 September 2024
polymerase II. The pre-snRNA are transcribed and receive the usual 7-methylguanosine five-prime cap in the nucleus. They are then exported to the cytoplasm...
17 KB (2,325 words) - 18:40, 12 September 2024
protein (VPg) covalently linked to 5' end of their genomes instead of 7-methylguanosine cap like cellular mRNAs. Virus RNA polymerases use VPg as primer....
32 KB (3,646 words) - 15:03, 14 September 2024
around the snRNA, the 5' terminal nucleoside (already modified to a 7-methylguanosine cap) is hyper-methylated to 2,2,7-trimethylguanosine and the other...
15 KB (1,819 words) - 00:38, 5 August 2024
(FapyG, FapyA) Alkylated bases: 3-methyladenine, 7-methylguanosine Deaminated bases: hypoxanthine formed from deamination of adenine...
29 KB (3,493 words) - 00:14, 22 June 2024
DNA methylation analysis. 5-Hydroxymethylcytosine 5-Methylcytosine 7-Methylguanosine Decrease in DNA Methylation I (DDM1), a plant methylation gene Demethylating...
114 KB (13,179 words) - 02:59, 22 July 2024
include 5′ capping, which is set of enzymatic reactions that add 7-methylguanosine (m7G) to the 5′ end of pre-mRNA and thus protect the RNA from degradation...
102 KB (11,438 words) - 16:50, 17 July 2024
S-adenosyl-L-methionine:mRNA (guanine-7-N-)-methyltransferase. cap MTase 7-Methylguanosine GRCh38: Ensembl release 89: ENSG00000101654 – Ensembl, May 2017 GRCm38:...
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Molecular function translation initiation factor activity RNA binding RNA 7-methylguanosine cap binding Cellular component cytoplasm mRNA cap binding complex...
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alkylation of bases (usually methylation), such as formation of 7-methylguanosine, 1-methyladenine, 6-O-Methylguanine hydrolysis of bases, such as deamination...
129 KB (15,900 words) - 06:12, 13 August 2024
utilizing alternative polyA sites have been described in the literature. 7-Methylguanosine GRCh38: Ensembl release 89: ENSG00000037897 – Ensembl, May 2017 GRCm38:...
4 KB (480 words) - 01:05, 4 March 2023
the nucleolus". Mol Cell. 9 (4): 891–901. doi:10.1016/S1097-2765(02)00484-7. PMID 11983179. "Entrez Gene: TGS1 trimethylguanosine synthase homolog (S...
6 KB (750 words) - 08:51, 29 December 2023
Tokuyama S, Suzuki Y, Ochi K (February 2007). "Loss of a conserved 7-methylguanosine modification in 16S rRNA confers low-level streptomycin resistance...
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transcribed in the nucleus, nearly all TERRA transcripts contain a 7-methylguanosine (m7G) cap structure at their 5' end. Therefore, the vast majority...
35 KB (4,668 words) - 11:25, 11 February 2024
Phizicky EM (2002). "Two proteins that form a complex are required for 7-methylguanosine modification of yeast tRNA". RNA. 8 (10): 1253–66. doi:10.1017/S1355838202024019...
4 KB (549 words) - 21:08, 18 February 2024
Cyclin-dependent kinase 7, or cell division protein kinase 7, is an enzyme that in humans is encoded by the CDK7 gene. The protein encoded by this gene...
20 KB (2,347 words) - 23:01, 27 March 2024