• Thumbnail for Acetylcholinesterase
    Acetylcholinesterase (HGNC symbol ACHE; EC 3.1.1.7; systematic name acetylcholine acetylhydrolase), also known as AChE, AChase or acetylhydrolase, is the...
    35 KB (3,881 words) - 18:15, 20 November 2024
  • Thumbnail for Acetylcholinesterase inhibitor
    Acetylcholinesterase inhibitors (AChEIs) also often called cholinesterase inhibitors, inhibit the enzyme acetylcholinesterase from breaking down the neurotransmitter...
    26 KB (2,387 words) - 03:29, 21 August 2024
  • Thumbnail for Cholinesterase inhibitor
    others. This group of inhibitors is divided into two subgroups, acetylcholinesterase inhibitors (AChEIs) and butyrylcholinesterase inhibitors (BChEIs)...
    13 KB (1,107 words) - 04:21, 2 November 2024
  • Thumbnail for Myasthenia gravis
    conduction study. MG is generally treated with medications known as acetylcholinesterase inhibitors, such as neostigmine and pyridostigmine. Immunosuppressants...
    82 KB (8,919 words) - 21:01, 2 November 2024
  • Thumbnail for Galantamine
    Galantamine (category Acetylcholinesterase inhibitors)
    Galantamine is a type of acetylcholinesterase inhibitor. It is an alkaloid extracted from the bulbs and flowers of Galanthus nivalis (common snowdrop)...
    35 KB (3,136 words) - 06:43, 7 September 2024
  • Thumbnail for Sarin
    Sarin (category Acetylcholinesterase inhibitors)
    acetylcholinesterase, allowing the muscle to relax. A build-up of acetylcholine in the synaptic cleft, due to the inhibition of acetylcholinesterase,...
    46 KB (4,655 words) - 20:47, 5 October 2024
  • Thumbnail for Cholinesterase
    broken down by a choline esterase. The main type for that purpose is acetylcholinesterase (also called choline esterase I or erythrocyte cholinesterase); it...
    17 KB (1,803 words) - 19:04, 26 March 2024
  • Nerve agent (category Acetylcholinesterase inhibitors)
    messages to organs. The disruption is caused by the blocking of acetylcholinesterase (AChE), an enzyme that catalyzes the breakdown of acetylcholine,...
    56 KB (6,500 words) - 08:10, 8 September 2024
  • Thumbnail for Malathion
    Malathion (category Acetylcholinesterase inhibitors)
    Malathion is an organophosphate insecticide which acts as an acetylcholinesterase inhibitor. In the USSR, it was known as carbophos, in New Zealand and...
    16 KB (1,448 words) - 07:30, 15 August 2024
  • Thumbnail for Huperzine A
    Huperzine A (category Acetylcholinesterase inhibitors)
    is a reversible acetylcholinesterase inhibitor and NMDA receptor antagonist that crosses the blood–brain barrier. Acetylcholinesterase is an enzyme that...
    14 KB (1,364 words) - 00:31, 7 September 2024
  • Thumbnail for VX (nerve agent)
    VX (nerve agent) (category Acetylcholinesterase inhibitors)
    talc thickening agent. VX is an acetylcholinesterase inhibitor. It blocks the function of the enzyme acetylcholinesterase (AChE). Normally, when a motor...
    48 KB (5,341 words) - 11:46, 19 November 2024
  • Thumbnail for Molluscicide
    are approved for use in organic gardening Metaldehyde Niclosamide Acetylcholinesterase inhibitors (e.g. methiocarb), highly toxic to other animals and humans...
    4 KB (345 words) - 03:07, 5 June 2024
  • Thumbnail for Carbamate
    insecticides kill insects by reversibly inactivating the enzyme acetylcholinesterase (AChE inhibition) (IRAC mode of action 1a). The organophosphate pesticides...
    30 KB (3,295 words) - 12:25, 14 November 2024
  • Thumbnail for Cholinergic
    concentration by using acetylcholinesterase inhibitors to inhibit acetylcholinesterase from breaking down acetylcholine. Current acetylcholinesterase inhibitors approved...
    9 KB (972 words) - 03:17, 10 September 2024
  • Thumbnail for Parathion
    Parathion (category Acetylcholinesterase inhibitors)
    Entwicklungsnummer (German for "development number"). It is an irreversible acetylcholinesterase inhibitor. Safety concerns later led to the development of parathion...
    13 KB (1,232 words) - 09:20, 27 September 2024
  • Thumbnail for Pyridostigmine
    Pyridostigmine (category Acetylcholinesterase inhibitors)
    Pyridostigmine is an acetylcholinesterase inhibitor in the cholinergic family of medications. It works by blocking the action of acetylcholinesterase and therefore...
    11 KB (923 words) - 05:16, 2 October 2024
  • Thumbnail for Physostigmine
    Physostigmine (category Acetylcholinesterase inhibitors)
    Fraser at the University of Edinburgh in 1862. Physostigmine, an acetylcholinesterase inhibitor, can be used to treat glaucoma and delayed gastric emptying...
    22 KB (2,359 words) - 05:20, 22 November 2024
  • Thumbnail for Pralidoxime
    compounds called oximes that bind to organophosphate-inactivated acetylcholinesterase. It is used to treat organophosphate poisoning in conjunction with...
    7 KB (678 words) - 08:59, 31 August 2024
  • Thumbnail for Suicide inhibition
    pesticides such as parathion are organophosphorus suicide inhibitors of acetylcholinesterase with aging times dependent on the lability of leaving groups present...
    5 KB (590 words) - 14:06, 30 October 2024
  • Thumbnail for Diisopropyl fluorophosphate
    Diisopropyl fluorophosphate (category Acetylcholinesterase inhibitors)
    medicine, and as an experimental agent in neuroscience because of its acetylcholinesterase inhibitory properties and ability to induce delayed peripheral neuropathy...
    10 KB (894 words) - 20:08, 30 August 2024
  • Thumbnail for Tomatine
    of the enzyme acetylcholinesterase. The majority of synthetic pesticides used in agriculture work by inhibition of acetylcholinesterase to kill insects...
    18 KB (2,070 words) - 18:46, 12 November 2024
  • Thumbnail for Acetylcholine
    the nucleus basalis of Meynert in the basal forebrain. The enzyme acetylcholinesterase converts acetylcholine into the inactive metabolites choline and...
    41 KB (4,382 words) - 05:15, 9 November 2024
  • Thumbnail for Fly spray
    that bind to and permanently block the action of an enzyme called acetylcholinesterase. Acetyl choline (ACh) is the nerve transmitter substance released...
    3 KB (333 words) - 00:39, 4 September 2024
  • Thumbnail for Rivastigmine
    Rivastigmine (category Acetylcholinesterase inhibitors)
    Rivastigmine, sold under the brand name Exelon among others, is an acetylcholinesterase inhibitor used for the treatment of dementia associated with Alzheimer's...
    21 KB (1,812 words) - 12:37, 12 October 2024
  • Thumbnail for Dementia
    (approximately one every three seconds). There is no known cure for dementia. Acetylcholinesterase inhibitors such as donepezil are often used and may be beneficial...
    205 KB (23,032 words) - 13:29, 19 November 2024
  • Thumbnail for Neostigmine
    Neostigmine (category Acetylcholinesterase inhibitors)
    cholinergic family of medications. It works by blocking the action of acetylcholinesterase and therefore increases the levels of acetylcholine. Neostigmine...
    18 KB (1,374 words) - 20:09, 30 August 2024
  • clinical laboratory tool to distinguish between the cholinesterases; acetylcholinesterase and butyrylcholinesterase preferentially lyse acetylcholine and butyrylcholine...
    2 KB (66 words) - 20:30, 5 November 2024
  • Thumbnail for Donepezil
    Donepezil (category Acetylcholinesterase inhibitors)
    incontinence, and seizures. Donepezil is a centrally acting reversible acetylcholinesterase inhibitor and structurally unrelated to other anticholinesterase...
    32 KB (2,840 words) - 22:22, 11 November 2024
  • Thumbnail for Three-finger toxin
    type. A class of 3FTx proteins called fasciculins bind the enzyme acetylcholinesterase and inhibit its activity by blocking access of acetylcholine to the...
    29 KB (3,346 words) - 16:07, 30 March 2024
  • Thumbnail for Susan Greenfield, Baroness Greenfield
    1977 under the supervision of Anthony David Smith on the Origins of acetylcholinesterase in cerebrospinal fluid. She then held a junior research fellowship...
    34 KB (2,839 words) - 01:59, 12 November 2024