An actin nucleation core is a protein trimer with three actin monomers. It is called a nucleation core because it leads to the energetically favorable...

as actin nucleation cores. However, the Arp2/3 complex stimulates actin polymerization by creating a new nucleation core. Actin nucleation is an initial...

protein-protein interactions. The nucleation of new actin filaments – the rate-limiting step in actin polymerization – is aided by actin-nucleating proteins such...

In cell biology, microtubule nucleation is the event that initiates de novo formation of microtubules (MTs). These filaments of the cytoskeleton typically...

actin cytoskeleton required for membrane ruffling. It has been shown to associate with an actin nucleation core Arp2/3 complex while enhancing actin polymerization...

Villin-1 is a 92.5 kDa tissue-specific actin-binding protein associated with the actin core bundle of the brush border. Villin-1 is encoded by the VIL1...

interact with the actin monomers while its CA domain interacts with the Arp2/3 complex, allowing the Arp2/3 complex to act as a nucleation core for the branching...

to determine the shape and movement of the plasma membrane. The nucleation of actin fibers occurs as a response to external stimuli, allowing a cell...

proteins, including the actin-binding protein profilin, SH3 (Src homology 3) domain proteins, and WW domain proteins. The actin nucleation-promoting activity...

polymerization Nucleation: A core of minimal 3 actin monomers is formed. Elongation: The core is used for elongation by addition of actin monomers. Steady...

Kabrawala S, Zimmer MD, Campellone KG (14 January 2020). "WHIMP links the actin nucleation machinery to Src-family kinase signaling during protrusion and motility"...

features: an actin core and a ring complex. Within the core, coordinators of actin nucleation are found. Specifically, the Arp2/3 complex and WASP when...

Transient Tic Disorder. WASHC2C is part of the WASH core complex where it functions as a nucleation-promoting factor (NPF) at the surface of endosomes...

they are released for transport into dendrites and axons after their nucleation in the centrosome. Therefore, both ends of the neurotubules terminates...

Actin-related protein 2 is a protein that in humans is encoded by the ACTR2 gene. The specific function of ACTR2 has not yet been determined. However...

creation of the double membrane (phagophore), which would be known as nucleation, is the first step in macro-autophagy. The phagophore approach indicates...

with mutations in the -synuclein (SNCA) gene. In the process of seeded nucleation, alpha-synuclein acquires a cross-sheet structure similar to other amyloids...

initiates the activation of retrograde trafficking and cargo capture. The nucleation complex is formed through the interaction of VPS complex with GTP-activated...

V, McPherson PS, Fremont DH (Feb 2006). "Structural definition of the F-actin-binding THATCH domain from HIP1R". Nat Struct Mol Biol. 13 (2): 121–30....

S2CID 104434042. Turkevich J, Stevenson PC, Hillier J (1951). "A study of the nucleation and growth processes in the synthesis of colloidal gold". Discuss. Faraday...

of polymers is known as polymerization and generally only occurs when nucleation sites are present and the concentration of monomers is sufficiently high...