Alpha granules, (α-granules) also known as platelet alpha-granules are a cellular component of platelets. Platelets contain different types of granules...

are found only in platelets and are smaller than alpha granules. The origin of these dense granules is still unknown, however, it is thought that may...

platelet alpha-granule deficiency, is a rare congenital autosomal recessive bleeding disorder caused by a reduction or absence of alpha-granules in blood...

Alpha-synuclein (aSyn) is a protein that, in humans, is encoded by the SNCA gene. Alpha-synuclein is a neuronal protein that regulates synaptic vesicle...

Examples of granules include granulocytes, platelet granules, insulin granules, germane granules, starch granules, and stress granules. A group of leukocytes...

physiology is the alpha-granule of platelets, which also contains vWF. Weibel–Palade bodies are the main source of vWF, while α-granules probably play a...

ultra-large VWF in endothelium (in the Weibel–Palade bodies), megakaryocytes (α-granules of platelets), and subendothelial connective tissue. The basic VWF monomer...

α2-Macroglobulin (α2M) or alpha-2-macroglobulin is a large (720 KDa) plasma protein found in the blood. It is mainly produced by the liver, and also locally...

Alpha-1 antitrypsin or α1-antitrypsin (A1AT, α1AT, A1A, or AAT) is a protein belonging to the serpin superfamily. It is encoded in humans by the SERPINA1...

PRF release several biologically active proteins including; platelet alpha granules, platelet‑derived growth factor (PDGF), transforming growth factors‑β...

deficient granules in platelets. Individuals with these disorders have too few or abnormally functioning alpha granules, delta granules, or both alpha and delta...

chemokine (C-X-C motif) ligand 4 (CXCL4) . This chemokine is released from alpha-granules of activated platelets during platelet aggregation, and promotes blood...

binding protein binding copper ion binding Cellular component platelet alpha granule extracellular vesicle endoplasmic reticulum lumen membrane plasma membrane...

to maintain a discoid shape Organelle zone — rich in platelet granules. Alpha granules contain clotting mediators such as factor V, factor VIII, fibrinogen...

Alpha 2-antiplasmin (or α2-antiplasmin or plasmin inhibitor) is a serine protease inhibitor (serpin) responsible for inactivating plasmin. Plasmin is...

granules called Weibel-Palade bodies. In unactivated platelets P-selectin is stored in α-granules. Other names for P-selectin include CD62P, Granule Membrane...

eosinophilic or "acid-loving" due to their large acidophilic cytoplasmic granules, which show their affinity for acids by their affinity to coal tar dyes:...

Fijalkowska I, Walkowiak B, Cierniewski CS (September 2001). "Acute phase protein alpha 1-acid glycoprotein interacts with plasminogen activator inhibitor type...

In the cellular biology, stress granules are biomolecular condensates in the cytosol composed of proteins and RNA that assemble into 0.1–2 μm membraneless...

small GTPases is a signal transduction pathway that triggers platelet alpha-granule release". Cell. 115 (7): 851–862. doi:10.1016/S0092-8674(03)01014-6...

defect in the secretion of the granule contents in neutrophils. There are other causes for a congenital platelet alpha-granule-deficient bleeding disorder...

the dense granules and alpha granules. From the dense granules, serotonin and adenosine diphosphate are released. From the alpha granules come molecules...

low-molecular-weight kininogen. Plasmin has been shown to interact with Thrombospondin 1, Alpha 2-antiplasmin and IGFBP3. Moreover, plasmin induces the generation of bradykinin...

Alpha-1-B glycoprotein is a 54.3 kDa protein in humans that is encoded by the A1BG gene. The protein encoded by this gene is a plasma glycoprotein of...

enzyme class is NDP-glucose:1,4-alpha-D-glucan 4-alpha-D-glucosyltransferase. Other names in common use include granule-bound starch synthase, starch synthase...

KL, Marshall-Carlson L, Bainton DF (July 1989). "GMP-140, a platelet alpha-granule membrane protein, is also synthesized by vascular endothelial cells...

endoplasmic reticulum-Golgi intermediate compartment membrane platelet alpha granule lumen Golgi membrane extracellular space Biological process hemostasis...

chain has been shown to interact with Lipoprotein(a). Fibrin Fibrinogen alpha chain Fibrinogen gamma chain GRCh38: Ensembl release 89: ENSG00000171564...

Alpha 1-antichymotrypsin (symbol α1AC, A1AC, or a1ACT) is an alpha globulin glycoprotein that is a member of the serpin superfamily. In humans, it is encoded...

functional heterodimers. Though PDGF is synthesized, stored (in the alpha granules of platelets), and released by platelets upon activation, it is also...