Amyloids are aggregates of proteins characterised by a fibrillar morphology of typically 7–13 nm in diameter, a β-sheet secondary structure (known as cross-β)...
60 KB (6,536 words) - 06:58, 4 November 2024
Amyloid beta (Aβ, Abeta or beta-amyloid) denotes peptides of 36–43 amino acids that are the main component of the amyloid plaques found in the brains...
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Amyloidosis (redirect from Amyloid degeneration)
Amyloidosis is a group of diseases in which abnormal proteins, known as amyloid fibrils, build up in tissue. There are several non-specific and vague signs...
53 KB (5,423 words) - 15:59, 20 December 2024
Amyloid plaques (also known as neuritic plaques, amyloid beta plaques or senile plaques) are extracellular deposits of amyloid beta (Aβ) protein that present...
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up amyloid in Wiktionary, the free dictionary. An amyloid is any of certain insoluble fibrous protein aggregates. Amyloid may also refer to: Amyloid (mycology)...
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AL amyloidosis (redirect from Amyloid light chain)
Amyloid light-chain (AL) amyloidosis, also known as primary amyloidosis, is the most common form of systemic amyloidosis. The disease is caused when a...
16 KB (1,638 words) - 20:43, 24 September 2024
Cerebral amyloid angiopathy (CAA) is a form of angiopathy in which amyloid beta peptide deposits in the walls of small to medium blood vessels of the...
18 KB (1,768 words) - 14:27, 21 August 2024
Amyloid-beta precursor protein (APP) is an integral membrane protein expressed in many tissues and concentrated in the synapses of neurons. It functions...
50 KB (5,683 words) - 22:54, 15 November 2024
accumulation of malformed protein deposits in the cerebral cortex, called amyloid plaques and neurofibrillary tangles. These misfolded protein aggregates...
186 KB (19,741 words) - 03:50, 6 January 2025
Amylin (redirect from Pro-islet amyloid polypeptide)
Amylin, or islet amyloid polypeptide (IAPP), is a 37-residue peptide hormone. It is co-secreted with insulin from the pancreatic β-cells in the ratio...
33 KB (4,024 words) - 07:27, 30 December 2024
Serum amyloid A (SAA) proteins are a family of apolipoproteins associated with high-density lipoprotein (HDL) in plasma. Different isoforms of SAA are...
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Amyloid: the Journal of Protein Folding Disorders is a peer-reviewed scientific journal that publishes original research and review articles on all aspects...
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Amyloid cardiomyopathy (stiff heart syndrome) is a condition resulting in the death of part of the myocardium (heart muscle). It is associated with the...
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Familial amyloid polyneuropathy, also called transthyretin-related hereditary amyloidosis, transthyretin amyloidosis abbreviated also as ATTR (hereditary...
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Amyloid purpura is a condition marked by bleeding under the skin (purpura) in some individuals with amyloidosis. Its cause is unknown, but coagulation...
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amyloidosis where there is depositing of the protein amyloid in the cardiac muscle and surrounding tissues. Amyloid, a misfolded and insoluble protein, can become...
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Sylvain Lesné (redirect from Amyloid beta star 56)
is the primary author of a controversial 2006 Nature paper, "A specific amyloid-β protein assembly in the brain impairs memory". Lesné's work in the 2006...
35 KB (3,545 words) - 10:23, 8 January 2025
protein has been identified as part of the enzymatic complex that cleaves amyloid-beta peptide from APP. The gene contains 14 exons, and the coding portion...
34 KB (3,741 words) - 05:07, 30 December 2024
In mycology a tissue or feature is said to be amyloid if it has a positive amyloid reaction when subjected to a crude chemical test using iodine as an...
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cellulose, "amyloid" actually is rich in protein. Subsequent research has shown that many different proteins can form amyloid, and that all amyloids show birefringence...
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Isolated atrial amyloidosis (redirect from Senile amyloid of atria of heart)
Isolated atrial amyloidosis is a form of amyloidosis affecting the atria of the heart.[citation needed] It is associated with accumulation of the protein...
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Lecanemab (category Anti-amyloid monoclonal antibodies)
medication used for the treatment of Alzheimer's disease. Lecanemab is an amyloid beta-directed antibody. It is given via intravenous infusion to patients...
30 KB (2,672 words) - 07:01, 6 December 2024
The serum amyloid P component (SAP) is the identical serum form of the amyloid P component (AP), a 25 kDa pentameric protein first identified as the pentagonal...
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AA amyloidosis (redirect from Amyloid associated)
tissues and organs. In AA amyloidosis, the deposited protein is serum amyloid A protein (SAA), an acute-phase protein which is normally soluble and whose...
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associated with amyloid diseases including wild-type transthyretin amyloidosis, hereditary transthyretin amyloidosis, familial amyloid polyneuropathy (FAP)...
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Amyloid-related imaging abnormalities (ARIA) are abnormal differences seen in magnetic resonance imaging of the brain in patients with Alzheimer's disease...
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can form a fibril, leading to abnormal protein aggregates called amyloids. These amyloids accumulate in infected tissue, causing damage and cell death. The...
100 KB (10,869 words) - 06:36, 6 January 2025
Familial amyloid cardiomyopathy (FAC), or transthyretin amyloid cardiomyopathy (ATTR-CM) results from the aggregation and deposition of mutant and wild-type...
7 KB (791 words) - 05:23, 19 October 2024
The familial amyloid neuropathies (or familial amyloidotic neuropathies, neuropathic heredofamilial amyloidosis, familial amyloid polyneuropathy) are a...
6 KB (505 words) - 14:56, 27 October 2023
Anti-amyloid drugs, also known as anti-amyloid antibodies (AAA), are a class of monoclonal antibodies developed to treat Alzheimer's disease. The first...
9 KB (2,453 words) - 23:13, 13 December 2024