• Thumbnail for Aquaporin-8
    Aquaporin-8 is a protein that in humans is encoded by the AQP8 gene. Aquaporin-8 (AQP-8) is a water channel protein. Aquaporins are a family of small...
    6 KB (630 words) - 23:50, 5 September 2023
  • Thumbnail for Aquaporin
    Aquaporins, also called water channels, are channel proteins from a larger family of major intrinsic proteins that form pores in the membrane of biological...
    38 KB (4,447 words) - 20:22, 27 June 2024
  • Thumbnail for Aquaporin-4
    Aquaporin-4, also known as AQP-4, is a water channel protein encoded by the AQP4 gene in humans. AQP-4 belongs to the aquaporin family of integral membrane...
    25 KB (3,030 words) - 00:27, 18 April 2024
  • Thumbnail for Aquaporin-3
    Aquaporin 3 (AQP-3) is the protein product of the human AQP3 gene. It is found in the basolateral cell membrane of principal collecting duct cells and...
    10 KB (1,239 words) - 00:22, 8 November 2023
  • Thumbnail for Aquaporin-2
    Aquaporin-2 (AQP-2) is found in the apical cell membranes of the kidney's collecting duct principal cells and in intracellular vesicles located throughout...
    12 KB (1,481 words) - 23:48, 8 April 2024
  • Thumbnail for Aquaporin-5
    Aquaporin-5 (AQP-5) is a protein that in humans is encoded by the AQP5 gene. Aquaporin-5 (AQP-5) is a water channel protein. Aquaporins are a family of...
    6 KB (782 words) - 19:39, 27 January 2023
  • Thumbnail for Aquaporin-1
    Aquaporin 1 (AQP-1) is a protein that in humans is encoded by the AQP1 gene. AQP-1 is a widely expressed water channel, whose physiological function has...
    10 KB (1,269 words) - 03:09, 1 December 2023
  • Thumbnail for Aquaporin-9
    Aquaporin-9 (AQP-9) is a protein that in humans is encoded by the AQP9 gene. The aquaporins/major intrinsic protein are a family of water-selective membrane...
    6 KB (745 words) - 18:14, 24 January 2024
  • than 80% of NMO cases, the cause is immunoglobulin G autoantibodies to aquaporin 4 (anti-AQP4), the most abundant water channel protein in the central...
    68 KB (7,255 words) - 20:09, 14 August 2024
  • Thumbnail for Aquaporin-6
    Aquaporin-6, (AQP-6) also known as kidney-specific aquaporin is a protein in humans that is encoded by the AQP6 gene. The protein encoded by this gene...
    3 KB (428 words) - 12:37, 21 January 2024
  • Thumbnail for Aquaporin-7
    Aquaporin-7 (AQP-7) is a protein that in humans is encoded by the AQP7 gene. Aquaporins/major intrinsic proteins (MIP) are a family of water-selective...
    7 KB (722 words) - 03:09, 1 December 2023
  • Thumbnail for Major intrinsic proteins
    MIP superfamily includes three subfamilies: aquaporins, aquaglyceroporins and S-aquaporins. The aquaporins (AQPs) are water selective. The aquaglyceroporins...
    23 KB (2,816 words) - 02:11, 29 November 2023
  • Thumbnail for Desmopressin
    translocation of aquaporin channels via cytosolic vesicles to the apical membrane of the collecting duct. The presence of these aquaporin channels in the...
    17 KB (1,518 words) - 18:20, 7 November 2023
  • Thumbnail for Vitreous body
    the area of the retina which provides finer detail and central vision. Aquaporin 4 in Müller cells in rats transports water to the vitreous body. The vitreous...
    18 KB (1,744 words) - 03:14, 27 May 2024
  • accomplished through convective bulk flow of ISF, facilitated by astrocytic aquaporin 4 (AQP4) water channels. The name "glymphatic system" was coined by the...
    28 KB (3,373 words) - 13:46, 21 July 2024
  • Thumbnail for Vasopressin
    cAMP, also increases transcription of the aquaporin-2 gene, thus increasing the total number of aquaporin-2 molecules in collecting duct cells. Increasing...
    45 KB (4,138 words) - 10:18, 12 August 2024
  • monomers can assemble to form the aquaporin proteins. As four of these monomers come together to form the aquaporin protein, it is known as a homotetramer...
    25 KB (2,646 words) - 00:12, 19 June 2024
  • Thumbnail for Nav1.8
    Nav1.8 is a sodium ion channel subtype that in humans is encoded by the SCN10A gene. Nav1.8-containing channels are tetrodotoxin (TTX)-resistant voltage-gated...
    29 KB (3,618 words) - 01:28, 27 August 2023
  • (May 2001). "Physiology and pathophysiology of renal aquaporins". Seminars in Nephrology. 21 (3): 231–8. doi:10.1053/snep.2001.21647. PMID 11320486. [needs...
    35 KB (4,047 words) - 07:14, 21 July 2024
  • Thumbnail for Diabetes insipidus
    convoluted tubules; specifically, it acts on proteins called aquaporins and more specifically aquaporin 2 in the following cascade. When released, ADH binds to...
    27 KB (2,782 words) - 12:25, 16 August 2024
  • been described in some patients with NMOSD who were negative for the aquaporin 4 (AQP-4) antibody. However, most NMOSD is an astrocytopathy, specifically...
    27 KB (2,799 words) - 22:15, 30 July 2024
  • Thumbnail for Colton antigen system
    called aquaporin-1 which is responsible for water homeostasis and urine concentration. The Co antigen is important in transfusion medicine. 99.8% of people...
    2 KB (246 words) - 05:15, 14 March 2022
  • Thumbnail for Transverse myelitis
    (March 2016). "Antibodies to myelin oligodendrocyte glycoprotein in aquaporin 4 antibody seronegative longitudinally extensive transverse myelitis:...
    29 KB (3,056 words) - 12:18, 15 May 2024
  • Thumbnail for Peter Agre
    cell membranes." Agre was recognized for his discovery of aquaporin water channels. Aquaporins are water-channel proteins that move water molecules through...
    37 KB (3,962 words) - 21:52, 30 April 2024
  • Thumbnail for Kidney
    expressed in proximal tubules, calbindin expressed in distal tubules and aquaporin 2 expressed in the collecting duct cells. The mammalian kidney develops...
    62 KB (6,946 words) - 15:38, 30 July 2024
  • microdomains in the cell’s plasma membrane. Through channels such as aquaporin or diffusion, hydrogen peroxide enters the cytosol. There, it oxidises...
    22 KB (2,555 words) - 10:14, 5 November 2023
  • diseases, are a group of diseases characterized by auto-antibodies against aquaporin 4. After the discovery of anti-AQP4 autoantibody in neuromyelitis optica...
    17 KB (1,889 words) - 20:08, 14 August 2024
  • disorder (NMOSD) in adults with a particular antibody (patients who are anti-aquaporin-4 or AQP4 antibody positive). Neuromyelitis optica spectrum disorder is...
    14 KB (1,143 words) - 06:40, 1 July 2024
  • Thumbnail for Urinary system
    collecting duct and distal convoluted tubule by inducing translocation of aquaporin-CD water channels in the kidney nephron collecting duct plasma membrane...
    16 KB (1,802 words) - 15:07, 1 July 2024
  • Thumbnail for Kangaroo rat
    concentrated urine, via a process apparently associated with expression of aquaporin 1 along a longer than usual segment of the descending limb of the loop...
    20 KB (2,262 words) - 16:00, 8 August 2024