Ataluren, sold under the brand name Translarna, is a medication for the treatment of Duchenne muscular dystrophy. It was designed by PTC Therapeutics....
21 KB (1,769 words) - 22:22, 12 July 2024
small molecule drugs such as aminoglycosides and negamycin. An oxadiazole, ataluren (previously PTC124), facilitates the selective read-through of aberrant...
25 KB (2,873 words) - 02:20, 25 September 2024
currently available including gene therapy (Elevidys), and antisense drugs (Ataluren, Eteplirsen etc.). Other medications used include glucocorticoids (Deflazacort...
65 KB (6,487 words) - 17:31, 7 October 2024
to dying muscle cells. These patients do not require antisense drugs (Ataluren, Eteplirsen etc.) as certain percentage of dystrophin is already expressed...
26 KB (2,551 words) - 21:03, 26 August 2024
currently available including gene therapy (Elevidys), and antisense drugs (Ataluren, Eteplirsen etc.). Other medications used include glucocorticoids (Deflazacort...
29 KB (2,231 words) - 00:04, 30 September 2024
the FDA in 2015. As of 2015, lumacaftor had no medical use on its own. Ataluren, targeting premature stop codons Kuk K, Taylor-Cousar JL (December 2015)...
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targeting RNA and approved drugs for human illness. Ribavirin, branaplam, and ataluren are currently available medications that stabilize double-stranded RNA...
65 KB (7,609 words) - 04:25, 14 October 2024
combinations M09AX01 Hyaluronic acid M09AX02 Chondrocytes, autologous M09AX03 Ataluren M09AX04 Drisapersen M09AX05 Aceneuramic acid M09AX06 Eteplirsen M09AX07...
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(deflazacort) from Marathon Pharmaceuticals. PTC also owns Translarna, (Ataluren) marketed for nonsense mutation Duchenne muscular dystrophy. Together,...
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with PTC that produced ataluren—Sweeney was the last author on the initial publication of ataluren in Nature in 2007. Ataluren was approved to treat DMD...
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(Abbott) Atacand atacicept (USAN, INN) ataciguat (INN) atagabalin (USAN, INN) ataluren (USAN, INN) atamestane (INN) ataprost (INN) Atapryl Atarax Atasol atazanavir...
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constitutive recognition. Ataluren is in clinical trials for the treatment of Duchenne Muscular Dystrophy (DMD). It is believed that Ataluren acts by promoting...
37 KB (4,392 words) - 04:20, 29 July 2024
membrane stained biopsies at baseline and either 24 or 48 weeks. As of 2016, ataluren was the only approved drug in the EU to treat a specific subpopulation...
11 KB (1,046 words) - 17:55, 24 March 2024
Nonsense mutations in the CDKL5 gene could be suppressed by compounds such as ataluren; (PTC Therapeutics), or similar next-generation translation stop readthrough...
25 KB (2,458 words) - 08:29, 3 July 2024
tested in young boys with Duchenne muscular Dystrophy aged 6 to 11 years. Ataluren Biostrophin (experimental) Idebenone (experimental) Spreitzer H (26 May...
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100 times or more. In 2009, his group's mechanistic studies of PTC124 (Ataluren), then in clinical trials for subclasses of cystic fibrosis and muscular...
12 KB (1,288 words) - 04:49, 2 July 2023
BioPharmaceuticals, Inc., with funding provided by the Muscular Dystrophy Association. Ataluren Rimeporide (experimental) Khurdayan VK, Bozzo J, Prous JR (Oct 2005). "Chronicles...
2 KB (184 words) - 21:53, 19 July 2023