AuTophaGy related 1 (Atg1) is a 101.7kDa serine/threonine kinase in S.cerevisiae, encoded by the gene ATG1. It is essential for the initial building of...
12 KB (1,464 words) - 17:22, 14 September 2023
other known players as Atg1, Atg13 and Atg17. Atg1 is a kinase upregulated upon induction of autophagy. Atg13 regulates Atg1 and together they form a...
7 KB (873 words) - 04:56, 19 July 2024
Rab1 mediates the recruitment of Atg1 to the PAS. Rab1 regulates macroautophagy by recruiting its effector, Atg1, to the PAS to tether Atg9 vesicles...
2 KB (248 words) - 19:07, 15 September 2021
important protein in autophagy for mammalian cells, and is homologous to ATG1 in yeast. It is part of the ULK1-complex, which is needed in early steps...
17 KB (1,930 words) - 14:55, 11 August 2024
phosphorylation of the Unc-51-like kinases ULK1 and ULK2 (mammalian homologues of Atg1). Induction of autophagy results in the dephosphorylation and activation...
77 KB (9,111 words) - 09:15, 16 October 2024
normally directly inhibits the function of the autophagy inducing kinase Atg1/ULK1. Thus, reducing TOR activity both reduces the global rate of translation...
37 KB (4,869 words) - 09:19, 17 May 2024
cytosol cytoplasm GATOR2 complex nucleotide-activated protein kinase complex Atg1/ULK1 kinase complex TORC2 complex Biological process mitochondrial DNA metabolic...
6 KB (774 words) - 13:56, 17 September 2023
-1, -2, and -3 (ULK1, ULK2, UKL3), which play a similar role as the yeast Atg1, act downstream of the mTOR complex. ULK1 and ULK2 form a large complex with...
55 KB (6,748 words) - 08:34, 28 October 2024
extracellular space guanyl-nucleotide exchange factor complex cytoplasm Atg1/ULK1 kinase complex axonal growth cone main axon P-body membrane axon dendrite...
31 KB (3,542 words) - 21:42, 15 September 2024
protein binding protein kinase binding Cellular component cytoplasm cytosol Atg1/ULK1 kinase complex mitochondrion phagophore assembly site endoplasmic reticulum...
7 KB (840 words) - 13:37, 18 January 2024
preventing it from entering the ULK1 kinase complex, which consists of Atg1, Atg17, and Atg101. This prevents the structure from being recruited to the...
69 KB (7,807 words) - 19:19, 19 September 2024
1953. VF-52 embarked on the USS Wasp for a WestPac deployment as part of ATG1 from 1 Sep 1954 to 11 Apr 1955. VF-52 embarked on the USS Lexington for a...
4 KB (405 words) - 01:21, 26 February 2024
site at serine 23. C1orf112 has been found experimentally to interact with ATG1, an aldosterone secretion whose overexpression characterizes certain forms...
17 KB (1,625 words) - 17:41, 25 April 2024
activity Cellular component phagophore assembly site membrane nuclear membrane Atg1/ULK1 kinase complex phagophore assembly site nucleus cytoplasm endoplasmic...
8 KB (1,051 words) - 02:57, 17 October 2022