• Autophagy is a monthly peer-reviewed scientific journal covering all aspects of cell autophagy. It is published by Taylor & Francis and the editor-in-chief...
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  • Thumbnail for Autophagy
    Autophagy (or autophagocytosis; from the Greek αὐτόφαγος, autóphagos, meaning "self-devouring" and κύτος, kýtos, meaning "hollow") is the natural, conserved...
    77 KB (9,111 words) - 09:15, 16 October 2024
  • Thumbnail for Yoshinori Ohsumi
    born February 9, 1945) is a Japanese cell biologist specializing in autophagy, the process that cells use to destroy and recycle cellular components...
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  • a mental disorder or a symptom of a mental disorder Autophagy (journal), a scientific journal Self-cannibalism, the practice of eating oneself This...
    341 bytes (74 words) - 00:04, 8 April 2022
  • Thumbnail for Chaperone-mediated autophagy
    Chaperone-mediated autophagy (CMA) refers to the chaperone-dependent selection of soluble cytosolic proteins that are then targeted to lysosomes and directly...
    31 KB (3,623 words) - 00:33, 22 June 2024
  • Thumbnail for Autophagy protein 5
    Autophagy protein 5 (ATG5) is a protein that, in humans, is encoded by the ATG5 gene located on chromosome 6. It is an E3 ubi autophagic cell death. ATG5...
    22 KB (2,808 words) - 09:48, 15 April 2024
  • autophagy, which specifically denotes the normal process of self-degradation by cells. While typically used only for this specific process, autophagy...
    13 KB (1,397 words) - 13:14, 20 September 2024
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    BNIP3 (section Autophagy)
    mitochondrial swelling and fission, and an increase in mitochondrial turnover via autophagy. Sequence similarity with Bcl-2 family members was not detected. Humans...
    21 KB (2,687 words) - 18:40, 24 September 2024
  • Mitophagy is the selective degradation of mitochondria by autophagy. It often occurs to defective mitochondria following damage or stress. The process...
    33 KB (4,128 words) - 02:28, 29 June 2024
  • Thumbnail for MTOR
    cell proliferation, cell motility, cell survival, protein synthesis, autophagy, and transcription. As a core component of mTORC2, mTOR also functions...
    119 KB (12,658 words) - 19:25, 19 September 2024
  • selective autophagy is a cellular process for the selective, ubiquitin-dependent degradation of chaperone-bound proteins in lysosomes. Autophagy (Greek:...
    11 KB (1,144 words) - 19:52, 3 May 2024
  • Thumbnail for MAP1LC3B
    the MAP1LC3B gene. LC3 is a central protein in the autophagy pathway where it functions in autophagy substrate selection and autophagosome biogenesis....
    40 KB (1,799 words) - 22:23, 2 December 2023
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    hepatitis C virus replication by chloroquine targeting virus-associated autophagy". Journal of Gastroenterology. 45 (2): 195–203. doi:10.1007/s00535-009-0132-9...
    46 KB (4,336 words) - 21:02, 21 June 2024
  • Thumbnail for Reactive oxygen species
    newer line of study has connected ROS levels and autophagy. ROS can also induce cell death through autophagy, which is a self-catabolic process involving...
    70 KB (8,489 words) - 08:42, 7 October 2024
  • prevent autophagy, while others utilize autophagy elements for intracellular development or cellular splitting. Macro autophagy, micro autophagy, and chaperon-mediated...
    41 KB (5,248 words) - 02:59, 24 October 2024
  • Thumbnail for Intracellular digestion
    Barth, Sandra; Macleod, Kay F. (2016-11-21). "Autophagy: cellular and molecular mechanisms". The Journal of Pathology. 221 (1): 3–12. doi:10.1002/path...
    5 KB (540 words) - 14:49, 29 June 2018
  • Thumbnail for BECN1
    encoded by the BECN1 gene. Beclin-1 is a mammalian ortholog of the yeast autophagy-related gene 6 (Atg6)  and BEC-1 in the C. elegans nematode. This protein...
    13 KB (1,482 words) - 16:14, 15 March 2024
  • Thumbnail for Valosin-containing protein
    (August 2012). "Expanding into new markets--VCP/p97 in endocytosis and autophagy". Journal of Structural Biology. 179 (2): 78–82. doi:10.1016/j.jsb.2012.03...
    49 KB (5,868 words) - 06:02, 3 June 2024
  • phosphatidylinositol 3-kinase/Akt/mTOR pathway and inhibition of autophagy". Journal of Virology. 87 (5): 2508–2517. doi:10.1128/JVI.02319-12. ISSN 0022-538X...
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  • Thumbnail for Lysosome
    endocytosis, while material from the inside of the cell is digested through autophagy. The sizes of the organelles vary greatly—the larger ones can be more...
    43 KB (4,709 words) - 13:50, 12 October 2024
  • of a cell as a result of events inside of a cell, such as apoptosis or autophagy. PCD is carried out in a biological process, which usually confers advantage...
    55 KB (6,748 words) - 08:34, 28 October 2024
  • Thumbnail for Ana Maria Cuervo
    Fred (6 October 2000). "Age-related Decline in Chaperone-mediated Autophagy". Journal of Biological Chemistry. 275 (40): 31505–31513. doi:10.1074/jbc.M002102200...
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  • Thumbnail for Spermidine
    theorized to promote autophagy via the MAPK pathway by inhibiting phosphorylation of raf, or possibly by inhibiting cytosolic autophagy-related protein acetylation...
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  • Thumbnail for Cell death
    organism of which the cells are part. Apoptosis or Type I cell-death, and autophagy or Type II cell-death are both forms of programmed cell death, while necrosis...
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  • Thumbnail for ULK1
    is an enzyme that in humans is encoded by the ULK1 gene. Unc-51-like autophagy-activating kinases 1 and 2 (ULK1/2) are two similar isoforms of an enzyme...
    17 KB (1,930 words) - 14:55, 11 August 2024
  • Expanded Scopus According to the Journal Citation Reports, the journal has a 5-year impact factor of 7.7. Autophagy Cell Biology International Cell and...
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  • Thumbnail for Crohn's disease
    the disease. Proposed mechanisms for smoking's effects include impaired autophagy, direct toxicity to immune cells, and changes in the microbiome. Diet...
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  • Thumbnail for AMBRA1
    (activating molecule in Beclin1-regulated autophagy) is a protein that is able to regulate cancer cells through autophagy. AMBRA1 is described as a mechanism...
    14 KB (1,490 words) - 22:00, 15 June 2024
  • Thumbnail for Goldilocks and the Three Bears
    229–32 Martin, S J (August 2011). "Oncogene-induced autophagy and the Goldilocks principle". Autophagy. 7 (8): 922–3. doi:10.4161/auto.7.8.15821. hdl:2262/73233...
    16 KB (1,778 words) - 20:25, 25 September 2024
  • Thumbnail for MTORC1
    MTORC1 (section Autophagy)
    "Context-Dependent Regulation of Autophagy by IKK-NF-κB Signaling: Impact on the Aging Process". International Journal of Cell Biology. 2012: 849541. doi:10...
    69 KB (7,807 words) - 19:19, 19 September 2024