protein-interacting protein 3 is a protein found in humans that is encoded by the BNIP3 gene. BNIP3 is a member of the apoptotic Bcl-2 protein family. It can induce cell...
21 KB (2,687 words) - 18:40, 24 September 2024
degeneration. It is mediated by Atg32 (in yeast) and NIX and its regulator BNIP3 in mammals. Mitophagy is regulated by PINK1 and parkin proteins. In addition...
33 KB (4,128 words) - 02:28, 29 June 2024
interact with: BAK1, BCAP31, BCL2-like 1, BCL2L11, BECN1, BID, BMF, BNIP2, BNIP3, BNIPL, BAD BAX, BIK, C-Raf, CAPN2, CASP8, Cdk1, HRK, IRS1, Myc, NR4A1,...
41 KB (4,564 words) - 08:17, 5 August 2024
buildup of damaged mitochondria is sufficient levels of the protein BNIP3. Deficiency of BNIP3 leads to muscle inflammation and atrophy. Furthermore, not every...
41 KB (4,722 words) - 06:37, 21 June 2024
this gene is a functional homolog of BNIP3, a proapoptotic protein. This protein may function simultaneously with BNIP3 and may play a role in tumor suppression...
7 KB (880 words) - 16:18, 13 October 2022
HGNC:30988 Q6ZN30 1605 BNIP1 HGNC:1082 Q12981 1606 BNIP2 HGNC:1083 Q12982 1607 BNIP3 HGNC:1084 Q12983 1608 BNIP3L HGNC:1085 O60238 1609 BNIP5 HGNC:33769 P0C671...
277 KB (17 words) - 23:17, 27 April 2024
lymphocytes by the process of mitophagy with the help of its regulator BNIP3. Using a gene knockout technique in mice, scientists have been able to attribute...
3 KB (440 words) - 20:47, 25 June 2020
cells. The BNIP3 pathway involves mitochondrial release and nuclear translocation of the endonuclease G. It is not clear, however, that how BNIP3 interacts...
19 KB (2,404 words) - 10:39, 22 March 2024
factors, such as IAPs and Bcl-2 proteins or prosurvival factors like cFLIP, BNIP3, FADD, Akt, and NF-κB. Many pathways and signals lead to apoptosis, but...
91 KB (10,653 words) - 17:23, 6 September 2024
degeneration. It is mediated by Atg32 (in yeast) and NIX and its regulator BNIP3 in mammals. Mitophagy is regulated by PINK1 and parkin proteins. The occurrence...
77 KB (9,112 words) - 23:14, 20 September 2024
amino-terminal targeting signal. ACAA2 has been shown to be a functional BNIP3 binding partner, which provides a possible link between fatty acid metabolism...
8 KB (1,125 words) - 13:37, 22 July 2023
1 (gene) has been shown to interact with: APAF1, BAK1, BCAP31, BCL2L11, BNIP3, BNIPL, BAD, BAX, BIK, Bcl-2, HRK, IKZF3, Noxa, PPP1CA, PSEN2 RAD9A, RTN1...
19 KB (2,223 words) - 05:29, 3 January 2024
TMEM101 interacting proteins (from IntAct database) Protein Description BNIP3 BCL2/adenovirus E1B 19 kDA protein-interacting protein 3 C4orf3 Uncharacterized...
20 KB (1,391 words) - 12:52, 18 August 2023
transplantation", published on Int Immunopharmacol. 2011 Expression of NOV and BNIP3 gene in mouse myelomonocytic leukemia and its significance 2011 Relationship...
22 KB (1,619 words) - 03:24, 30 June 2024
(1999). "BNIP3alpha: a human homolog of mitochondrial proapoptotic protein BNIP3". Cancer Res. 59 (3): 533–7. PMID 9973195. Wang HG, Pathan N, Ethell IM...
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oligomerization of hBok are triggered in response to apoptotic stimuli and Bnip3" (PDF). Cellular and Molecular Life Sciences. 62 (9): 1015–24. doi:10...
14 KB (1,775 words) - 00:12, 24 July 2022
Aryl hydrocarbon receptor CLOCK CREBBP CRY1 EP300 EPAS1 HIF1A NPAS2 SUMO3 BNIP3 Arntl2 - Arntl2 (Bmal2) is a paralog of Arntl (Bmal1) that encodes for a...
48 KB (5,652 words) - 07:34, 3 June 2024
malignant glioma cells by up-regulation of mitochondrial cell death protein BNIP3. Oncogene 24: 980-91, 2005. PMID 15592527 Germano IM,Gracies JM, Weisz DJ...
13 KB (1,625 words) - 16:48, 16 August 2024
cells overexpressing a dominant-negative mutant of a pro-apoptotic BNIP3 (TM-BNIP3) were largely resistant to Brevinin-2R treatment. These 25 amino acid...
52 KB (6,603 words) - 06:30, 10 August 2024
1999). "BNIP3alpha: a human homolog of mitochondrial proapoptotic protein BNIP3". Cancer Research. 59 (3): 533–7. PMID 9973195. Human BNIPL genome location...
4 KB (501 words) - 01:44, 6 September 2023