• Thumbnail for Benzyl chloroformate
    Benzyl chloroformate, also known as benzyl chlorocarbonate or Z-chloride, is the benzyl ester of chloroformic acid. It can be also described as the chloride...
    10 KB (920 words) - 21:29, 12 November 2023
  • Thumbnail for Chloroformate
    methyl chloroformate, which is commercially available. Chloroformates are used as reagents in organic chemistry. For example, benzyl chloroformate is used...
    2 KB (319 words) - 16:52, 20 December 2023
  • Chloroformic acid (category Chloroformates)
    Important chloroformate esters include 4-nitrophenyl chloroformate, fluorenylmethyloxycarbonylchloride, benzyl chloroformate and ethyl chloroformate. Chloroacetic...
    4 KB (229 words) - 16:12, 19 April 2024
  • Thumbnail for Benzyl group
    IUPAC nomenclature, the prefix benzyl refers to a C6H5CH2 substituent, for example benzyl chloride or benzyl benzoate. Benzyl is not to be confused with phenyl...
    15 KB (1,604 words) - 15:45, 3 December 2023
  • Thumbnail for Peptide synthesis
    Leonidas Zervas in the early 1930s and usually added via reaction with benzyl chloroformate. It is removed under harsh conditions using HBr in acetic acid, or...
    54 KB (6,100 words) - 16:21, 3 August 2024
  • Thumbnail for Benzyl carbamate
    ester of carbamic acid (O=C(OH)(NH2)) and benzyl alcohol, although it is produced from benzyl chloroformate with ammonia. It is a white solid that is...
    2 KB (143 words) - 08:55, 8 October 2022
  • Thumbnail for Phosgene
    hydrogen chloride side-product. Phosgene is used to produce chloroformates such as benzyl chloroformate: R−OH + COCl2 → R−O−C(=O)−Cl + HCl In these syntheses...
    30 KB (3,150 words) - 04:36, 25 July 2024
  • Thumbnail for Carbamate
    common amine protecting groups, such as BOC, FMOC, benzyl chloroformate and trichloroethyl chloroformate are carbamates. Urethane (ethyl carbamate) was once...
    30 KB (3,295 words) - 14:42, 16 July 2024
  • Thumbnail for Magnesium oxide
    reagent in the installation of the carboxybenzyl (Cbz) group using benzyl chloroformate in EtOAc for the N-protection of amines and amides. Doping MgO (about...
    24 KB (2,438 words) - 14:51, 24 July 2024
  • Thumbnail for Achmatowicz reaction
    1021/jo702006z. ISSN 0022-3263. PMC 2652699. PMID 18171075. Reagents: benzyl chloroformate protects amine as Cbz group, Achmatowitz reaction with m-CPBA, complexation...
    4 KB (436 words) - 00:35, 9 July 2022
  • Chloromethyl chloroformate Dibenzoxazepine (CR) Ethyl iodoacetate Ortho-chlorobenzylidene malononitrile (Super tear gas; CS) Trichloromethyl chloroformate Xylyl...
    7 KB (899 words) - 00:03, 9 January 2024
  • g/mol, exact mass: 170.0135 u) may refer to: Anisoyl chloride Benzyl chloroformate, or benzyl chlorocarbonate This set index page lists chemical structure...
    328 bytes (60 words) - 12:37, 20 April 2021
  • Thumbnail for Ester
    as an inorganic compound) Chloroformic acid forms chloroformate esters, e.g. methyl chloroformate (Cl−C(=O)−O−CH3) (if one classifies chloroformic acid...
    42 KB (4,411 words) - 15:43, 18 July 2024
  • Benzimidazole, 4,5-dichloro-2-(trifluoromethyl)- Benzotrichloride Benzyl chloride Benzyl cyanide Bicyclo(2.2.1)heptane-2-carbonitrile Bis(chloromethyl) ketone...
    10 KB (825 words) - 17:27, 31 July 2024
  • Thumbnail for Oseltamivir total synthesis
    Pyridine (1) is reduced with sodium borohydride in presence of benzyl chloroformate to the Cbz protected dihydropyridine 2. The asymmetric Diels-Alder...
    20 KB (2,309 words) - 12:58, 25 October 2023
  • chloride UN 1737 6.1 Benzyl bromide UN 1738 6.1 Benzyl chloride or Benzyl chloride unstabilized UN 1739 8 Benzyl chloroformate UN 1740 8 Hydrogen difluorides...
    7 KB (159 words) - 17:06, 14 March 2022
  • carboxybenzyl group discovered by Zervas is introduced by reaction with benzyl chloroformate, originally in aqueous sodium carbonate solution at 0 °C: The protecting...
    20 KB (1,840 words) - 21:30, 12 November 2023
  • acid 1878-68-8 C8H7ClO benzeneacetyl chloride 103-80-0 C8H7ClO2 benzyl chloroformate 501-53-1 C8H7F2NO difluoroacetanilide 404-17-1 C8H7F7O3 ethyl...
    25 KB (28 words) - 04:59, 24 October 2023
  • Thumbnail for Lacosamide
    Lacosamide (category Benzyl compounds)
    acid. The product is treated first with N-methylmorpholine, isobutyl chloroformate, and benzylamine, next with methyl iodide and silver oxide, forming...
    40 KB (3,797 words) - 04:47, 25 July 2024
  • Thumbnail for Protecting group
    a benzyl ester on the carboxyl group, a fluorenylmethylenoxy carbamate on the amine group, and a tert-butyl ether on the phenol group. The benzyl ester...
    57 KB (6,755 words) - 23:19, 9 April 2024
  • Thumbnail for Teniloxazine
    hydride affords 4-Benzyl-2-({2-[(thiophen-2-yl)methyl]phenoxy}methyl)morpholine [62473-77-2] (5). Treatment with Ethyl chloroformate [541-41-3] (6) gives...
    8 KB (745 words) - 14:36, 9 June 2024
  • Thumbnail for Di-tert-butyl dicarbonate
    groups such as the benzyloxycarbonyl, 9-fluorenylmethoxycarbonyl, O- and S-benzyl and t-butylthio groups. The synthesis of 6-acetyl-1,2,3,4-tetrahydropyridine...
    13 KB (1,222 words) - 20:59, 16 December 2023
  • Thumbnail for Torcetrapib
    then protected as its ethyl carbamate by acylation with ethyl chloroformate (6). The benzyl carbamate function on nitrogen at the 4 position is next removed...
    18 KB (1,638 words) - 20:03, 20 December 2023
  • Thumbnail for Polycarbonate
    H2O The diphenoxide (Na2(OC6H4)2CMe2) reacts with phosgene to give a chloroformate, which subsequently is attacked by another phenoxide. The net reaction...
    39 KB (3,774 words) - 15:56, 23 July 2024
  • Thumbnail for Chemical weapons in World War I
    Both Benzyl bromide 1915 Lachrymatory Central Powers Chloromethyl chloroformate 1915 Irritant – Eyes, skin, lungs Both Trichloromethyl chloroformate 1916...
    86 KB (10,196 words) - 14:46, 18 June 2024
  • Thumbnail for Carbonyl group
    carbonyls are urea and the carbamates, the derivatives of acyl chlorides chloroformates and phosgene, carbonate esters, thioesters, lactones, lactams, hydroxamates...
    9 KB (875 words) - 20:45, 15 July 2024
  • Thumbnail for RTI-274
    halogenated, the amide is prepared, and reduced. (a) (1) 1-chloroethyl chloroformate, 1,2-dichloroethane, reflux; (2) MeOH reflux; (b) p-toluenesulfonyl...
    6 KB (477 words) - 05:59, 21 June 2022
  • Thumbnail for Strychnine total synthesis
    were combined in an amine-carbonyl condensation followed by methyl chloroformate quench to triene 3 which was then reacted in a Diels–Alder reaction...
    39 KB (4,087 words) - 03:50, 29 February 2024
  • chloride 33631-63-9 C7H13ClO heptanoyl chloride 2528-61-2 C7H13ClO2 hexyl chloroformate 6092-54-2 C7H13LiO2 lithium heptanoate 16761-13-0 C7H13N diethylpropargylamine...
    20 KB (28 words) - 01:35, 26 June 2024
  • Thumbnail for Enders SAMP/RAMP hydrazone-alkylation reaction
    substantial minor product. Certain electrophiles also elicit nitriles: chloroformates, strongly-activated alkynes, or methyl iodide and a hindered base. Methyl...
    23 KB (2,515 words) - 20:33, 22 July 2024