Beta-defensin 2 (BD-2) also known as skin-antimicrobial peptide 1 (SAP1) is a peptide that in humans is encoded by the DEFB4 (defensin, beta 4) gene. Human...
11 KB (1,444 words) - 19:40, 16 May 2024
Beta defensins are a family of vertebrate defensins. The beta defensins are antimicrobial peptides implicated in the resistance of epithelial surfaces...
13 KB (1,496 words) - 03:19, 29 August 2024
antimicrobial activity. Theta defensins form a single beta-hairpin structure and represent a distinct group. Only alpha and beta-defensins are expressed in humans...
34 KB (3,453 words) - 03:33, 27 May 2024
Beta-defensin 1 is a protein that in humans is encoded by the DEFB1 gene. Defensins form a family of microbicidal and cytotoxic peptides made by neutrophils...
9 KB (1,007 words) - 19:51, 17 January 2024
Beta-defensin 3 is a protein that in humans is encoded by the DEFB3 gene. HBD-3 was first isolated from human lesional psoriatic scales. RT-PCR showed...
1 KB (139 words) - 06:59, 19 December 2023
chimpanzee. Structure of human retrocyclin-2 θ-defensin θ-defensins are cyclic peptides of 18 amino acids (~2 kDa), possessing antimicrobial activity against...
9 KB (972 words) - 06:22, 17 November 2023
Plant defensins (formerly gamma-thionins) are a family of primitive, highly stable, cysteine-rich defensins found in plants that function to defend them...
35 KB (3,924 words) - 03:22, 27 May 2024
pattern of disulfide bonding, mammalian defensins are classified into alpha, beta and theta categories. Alpha-defensins, which have been identified in humans...
16 KB (1,903 words) - 12:49, 28 August 2024
secreted in human milk activates PAR-2 receptors, of intestinal epithelial cells HT-29, and promotes beta-defensin-2 expression. Immunology letters, 123(1)...
7 KB (793 words) - 03:06, 16 September 2024
mesenchymal stem cells against Escherichia coli is mediated by secretion of beta- defensin- 2 via toll- like receptor 4 signalling". Cellular Microbiology. 18 (3):...
43 KB (4,871 words) - 19:58, 21 November 2024
targeting cell membrane lipids as part of their function. In fact human beta-defensin 2 have now been shown to kill the pathogenic fungi Candida albicans through...
61 KB (6,549 words) - 03:13, 28 September 2024
expressed in basal cells. Other innate immune mediators include beta-defensin 2, and lipocalin-2; pro-inflammatory cytokines, interleukins IL6, and IL8; and...
9 KB (1,101 words) - 18:32, 16 September 2024
Arthropod defensins are a family defensin proteins found in mollusks, insects, and arachnids. These cysteine-rich antibacterial peptides are primarily...
12 KB (1,256 words) - 06:08, 17 November 2023
EF (2006). "A Chromosome 8 Gene-Cluster Polymorphism with Low Human Beta-Defensin 2 Gene Copy Number Predisposes to Crohn Disease of the Colon". Am J Hum...
8 KB (779 words) - 03:43, 11 December 2023
Transforming growth factor beta (TGF-β) is a multifunctional cytokine belonging to the transforming growth factor superfamily that includes three different...
67 KB (8,184 words) - 20:48, 31 October 2024
Cammarota M, Alfano A, Schiraldi C, Donnarumma G (2017). "Beta-Defensin-2 and Beta-Defensin-3 Reduce Intestinal Damage Caused by Salmonella typhimurium...
27 KB (3,269 words) - 12:47, 13 February 2024
Beta-defensin 126 is a protein that in humans is encoded by the DEFB126 gene. Defensins are cysteine-rich cationic polypeptides that are important in...
4 KB (439 words) - 20:47, 19 August 2023
the expression of pro-inflammatory cytokines, chemokines and human beta-defensin-2 in vaginal epithelial cells, MICROBES AND INFECTION 7: (9-10) pp. 1117–1127...
14 KB (1,594 words) - 20:46, 16 February 2023
activated the epithelial cells in culture to produce beta-defensin 2 (hBD2) and beta defensins 4 (hBD4). These findings suggest that TFF can activate...
15 KB (1,649 words) - 23:20, 27 March 2024
DEFB127 (category Defensins)
Beta-defensin 127 is a protein that in humans is encoded by the DEFB127 gene. Defensins are cysteine-rich cationic polypeptides that are important in...
4 KB (437 words) - 20:48, 19 August 2023
Beta-defensin 129 is a protein that in humans is encoded by the DEFB129 gene. Defensins are cysteine-rich cationic polypeptides that are important in...
4 KB (433 words) - 20:47, 19 August 2023
Suico MA, Shuto T, Li JD, Kai H (March 2004). "MEF up-regulates human beta-defensin 2 expression in epithelial cells". FEBS Letters. 561 (1–3): 117–21. Bibcode:2004FEBSL...
5 KB (602 words) - 05:46, 25 July 2024
DEFB103A (category Defensins)
Beta-defensin 103 is a protein that in humans is encoded by the DEFB103A gene. Defensins form a family of microbicidal and cytotoxic peptides made by neutrophils...
8 KB (1,035 words) - 06:16, 17 November 2023
DEFA5 (category Defensins)
Defensin, alpha 5 (DEFA5) also known as human alpha defensin 5 (HD5) is a protein that in humans is encoded by the DEFA5 gene. DEFA5 is expressed in the...
9 KB (1,031 words) - 21:44, 20 October 2024
microbiological assay originally developed to measure the activity of defensins. It has since been applied to other antimicrobial peptides including LL-37...
29 KB (4,186 words) - 02:21, 3 May 2024
DEFB119 (category Defensins)
Beta-defensin 119 is a protein that in humans is encoded by the DEFB119 gene. GRCh38: Ensembl release 89: ENSG00000180483 – Ensembl, May 2017 GRCm38:...
3 KB (387 words) - 19:30, 28 December 2023
DEFA6 (category Defensins)
Defensin, alpha 6 (DEFA6) also known as human alpha defensin 6 (HD6) is a human protein that is encoded by the DEFA6 gene. DEFA6 is expressed in the Paneth...
5 KB (568 words) - 06:13, 17 November 2023
Lingual antimicrobial peptide (LAP) is a beta-defensin found in bovine internal epithelial tissue, in particular, that of the digestive tract. It has...
3 KB (295 words) - 22:35, 7 September 2021
It was discovered that a gene mutation responsible for the protein beta-defensin 3, known as the K locus, is responsible for the black coat colour in...
20 KB (2,380 words) - 19:09, 23 April 2024
vivo following alkali injury. Exp Eye Res, 2002. 74(2): p. 293-9. Gottsch, J.D., et al., Defensin gene expression in the cornea. Curr Eye Res, 1998. 17(11):...
12 KB (1,800 words) - 17:42, 3 December 2023