NEDD8-dissociated protein 1 is a protein that in humans is encoded by the CAND1 gene. CAND1 has been shown to interact with: CUL1, CUL2, CUL3, CUL4A, CUL4B, DCUN1D1...
7 KB (959 words) - 22:02, 2 December 2023
D) = Cand1 * min(dA1, dA2, ..., dAn) + Cand2 * max(dA1, dA2 ..., dAn) where Cor1, Cor2 are "softness" coefficients for the or operator, and Cand1, Cand2...
9 KB (1,204 words) - 21:36, 15 September 2024
Q9P1Y5 2116 CAMTA1 HGNC:18806 Q9Y6Y1 2117 CAMTA2 HGNC:18807 O94983 2118 CAND1 HGNC:30688 Q86VP6 2119 CAND2 HGNC:30689 O75155 2120 CANT1 HGNC:19721 Q8WVQ1...
277 KB (17 words) - 18:34, 6 October 2024
1038/nature05175 Goldenberg, S.J., Cascio, T.C., Shumway, S.D. et al. Structure of the Cand1-Cul1-Roc1 complex reveals regulatory mechanisms for the assembly of the...
11 KB (965 words) - 18:16, 21 June 2024
two groups: cullins and non-cullins. Cullins, when neddylated, release CAND1 from its inhibitory binding, and that leads to the activation of Cullin...
4 KB (589 words) - 11:55, 8 October 2024
with RNF7. Part of a complex with TIP120A/CAND1 and RBX1. The unneddylated form interacts with TIP120A/CAND1 and the interaction negatively regulates the...
8 KB (1,072 words) - 18:21, 22 December 2023
regulation of protein turn-over. RBX1 has been shown to interact with: CAND1, CUL1, CUL2, CUL4A, CUL5 CUL7, DCUN1D1, and P70-S6 Kinase 1. GRCh38: Ensembl...
13 KB (1,550 words) - 01:52, 11 April 2024
their discoveries relating to the CRL regulators COP9 signalosome (CSN) and CAND1. In 2001-2002, the Deshaies lab showed that CSN, together with proteasome...
18 KB (2,482 words) - 05:06, 15 February 2024
NEDD8 and cullin protein. Another protein that interacts with cullin is CAND1 which binds to deneddylated form of cullin protein and disrupts the interaction...
20 KB (2,380 words) - 07:40, 8 October 2024
degradation A subunit and holoenzyme of PP2A SCFubiquitin ligase regulator Cand1 Hsm3, a molecular chaperon involved in the assembly of 26Sproteasome Nucleo-cytoplasmic...
25 KB (3,022 words) - 17:42, 26 April 2024
by CRL4 complexes. Human CUL4A forms direct interactions with: DDB1 RBX1 CAND1 The COP9 signalosome Human CUL4A-DDB1-RBX1 complexes promote the ubiquitination...
36 KB (4,418 words) - 03:28, 3 December 2023
Garbutt KC, Liu J, Xiong Y, Zheng N (November 2004). "Structure of the Cand1-Cul1-Roc1 complex reveals regulatory mechanisms for the assembly of the...
7 KB (718 words) - 21:57, 20 September 2023
microRNA that promotes LNCaP prostate cell growth by repressing its target CAND1 expression". Prostate Cancer Prostatic Dis. 13 (4): 356–61. doi:10.1038/pcan...
5 KB (694 words) - 11:58, 3 December 2023
targeted by CRL4 complexes. Human CUL4B forms direct interactions with: RBX1 CAND1 DDB1 and the COP9 signalosome Human CUL4B-DDB1-RBX1 complexes promote the...
23 KB (2,948 words) - 23:56, 9 September 2023
humans is encoded by the CUL2 gene. CUL2 has been shown to interact with: CAND1, DCUN1D1, RBX1, SAP130, TCEB2 and Von Hippel-Lindau tumor suppressor. GRCh38:...
11 KB (1,418 words) - 03:27, 3 December 2023
Matsumoto T, Xiong Y (2003). "NEDD8 modification of CUL1 dissociates p120(CAND1), an inhibitor of CUL1-SKP1 binding and SCF ligases". Mol. Cell. 10 (6):...
10 KB (1,305 words) - 00:20, 24 December 2023
oncogenic driver in cancer cells. DCUN1D1 has been shown to interact with: CAND1, CUL1, CUL2, CUL3 and RBX1. GRCh38: Ensembl release 89: ENSG00000043093...
7 KB (969 words) - 06:24, 3 January 2024