CD1a (Cluster of Differentiation 1a) is a human protein encoded by the CD1A gene. This gene encodes a member of the CD1 family of transmembrane glycoproteins...
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of tissue-derived CD1a-presented autoantigens and the first CD1a-lipid-TCR structure, between an autoreactive TCR which bound the CD1a without contacting...
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interstitial lung disease. PLCH develops when an abundance of monoclonal CD1a-positive Langerhans (immature histiocytes) proliferate the bronchioles and...
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but have undergone further differentiation. Skin Langerhans cells express CD1a, as do cortical thymocytes (cells of the cortex of the thymus gland). They...
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ways. Unlike LCH, ECD does not stain positive for S-100 proteins or Group 1 CD1a glycoproteins, and electron microscopy of cell cytoplasm does not disclose...
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"Staphylococcal phosphatidylglycerol antigens activate human T cells via CD1a". Nature Immunology. 24 (1): 110–122. doi:10.1038/s41590-022-01375-z. PMC 10389259...
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1501141. PMID 26416282. Wilson, AJ; Maddox, PH; Jenkins, D (January 1991). "CD1a and S100 antigen expression in skin Langerhans cells in patients with breast...
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histiocytes will be positive for S100, CD68, and CD163 but negative for CD1a. In 2016 the Histiocyte Society proposed a classification of histiocytoses...
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nutritional predisposition to the disease.". On the other hand, reduced CD1a+ Langerhans cells and CD207+ dendritic cells indicate evolving immunosuppression...
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molecule. Humans express four CD1 isoforms divided in 2 groups: group 1 CD1 (CD1a, CD1b, and CD1c) group 2 CD1 (CD1d). Group 1 CD1-restricted T cells express...
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the lung parenchyma; the expression levels of a panel of seven genes (KMO, CD1A, SPINK5, TREM2, CYBB, DNASE2B, FGG) are increased in the lung tissue of smokers...
130 KB (14,348 words) - 08:31, 11 November 2024
"Staphylococcal phosphatidylglycerol antigens activate human T cells via CD1a". Nature Immunology. 24 (1): 110–122. doi:10.1038/s41590-022-01375-z. PMC 10389259...
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defined by their ability to recognize antigens bound on group 1 CD1 molecules (CD1a, CD1b and CD1c) with their TCR. Natural killer T (NKT) cells are a similar...
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(June 2006). "40 nm, but not 750 or 1,500 nm, nanoparticles enter epidermal CD1a+ cells after transcutaneous application on human skin". The Journal of Investigative...
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1 RECEPTOR (VIPR) PEPTIDE (RESIDUES 400-408) 1onq: Crystal Structure of CD1a in Complex with a Sulfatide 1p7q: Crystal Structure of HLA-A2 Bound to LIR-1...
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lipid molecules CD1a CD1a (Cluster of Differentiation 1a), or T-cell surface glycoprotein CD1a, is a human protein encoded by the CD1A gene. An antigen-presenting...
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IRMNG: 1367600 ITIS: 1125406 NCBI: 227090 Open Tree of Life: 236036 Paleobiology Database: 249809 Plazi: 8F7087F7-FF87-CD1A-FC97-6D06DFA2FC6A uBio: 5547857...
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HGNC:15553 Q96SF2 2483 CCZ1 HGNC:21691 P86791 2484 CCZ1B HGNC:21717 P86790 2485 CD1A HGNC:1634 P06126 2486 CD1B HGNC:1635 P29016 2487 CD1C HGNC:1636 P29017 2488...
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with Langerhans cells as they uniquely express CD14 and FXIIIa and lack CD1a. The prenatal portion of tissue-resident dermal macrophages is produced from...
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typically positive for pan-T antigens CD2, CD3, and CD7 and negative for TdT and CD1a. The immunophenotype CD4+/CD8- is present in 60% of cases, the CD4+/CD8+...
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Life: 7475 Plazi: E00DA31A-1C07-FFDF-08AB-27D84DB9FDDD uBio: 4100652 WSC: urn:lsid:nmbe.ch:spidergen:00004 ZooBank: C27B0E39-CD1A-47BD-9815-F3D47EBB0730...
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National Library of Medicine Medical Subject Headings (MeSH) Human CD1A genome location and CD1A gene details page in the UCSC Genome Browser. Human CD1D genome...
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histiocytomas have the phenotype of epidermal Langerhans cells. They express CD1a, CD1b, CD1c, MHC class II, CD11c, and E-cadherin. Amongst leukocytes, E-cadherin...
16 KB (2,179 words) - 23:09, 17 October 2023
687837 IUCN: 61290 NCBI: 134591 Open Tree of Life: 1092119 Plazi: 1F03FA11-CD1A-5563-AB8F-40DCDD7B1AF3 WoRMS: 1010725 ZooBank: 0ADAB74E-0438-4B5F-9121-505AFB5EFBCC...
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"Staphylococcal phosphatidylglycerol antigens activate human T cells via CD1a". Nature Immunology. 24 (1): 110–122. doi:10.1038/s41590-022-01375-z. PMC 10389259...
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cDCs can be subdivided into 3 groups: monocyte-derived DCs, CD1a- interstitial DCs, and CD1a+ Langerhans cells. Plasmacytoid dendritic cells (pDCs) differentiate...
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lack Birbeck granules but are characteristically positive for S-100 and CD1a. Clinically, ICH is defined by pink to reddish, varying-sized, painless,...
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CD1 locus is found on chromosome 1 and contains five nonpolymorphic genes (CD1a, CD1b, CD1c, CD1d and CD1e). CD1b molecules (as well as other CD1 and classical...
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Extramammary Paget's disease Microcystic adnexal carcinoma Eccrine poroma CD1a Langerhans cell Langerhans cell histiocytosis Indeterminate cell histiocytosis...
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inside the Birbeck granules, it contributes to the binding of the antigen to CD1a molecule. In mice, langerin is involved in antigen binding to MHC II glycoproteins...
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