CDKAL1 (Cdk5 regulatory associated protein 1-like 1) is a gene in the methylthiotransferase family. The complete physiological function and implications...
10 KB (1,118 words) - 03:54, 9 December 2023
one of her studies, she concludes that the gene variant rs7754840 of the CDKAL1 gene (known to inhibit insulin production) does not increase susceptibility...
14 KB (1,285 words) - 07:51, 10 March 2024
linked to birth weight, ADCY5 and CCNL1, and four that show some evidence (CDKAL1, HHEX–IDE, GCK, and TCF7L2). The heritability of birth weight ranges from...
39 KB (4,384 words) - 23:07, 7 October 2024
frame 62 (6p22.3) C6orf89: chromosome 6 open reading frame 89 (6p21.2) CDKAL1: CDK5 regulatory subunit associated protein 1 like 1 (6p22.3) COL11A2: collagen...
35 KB (2,420 words) - 20:57, 24 August 2024
HGNC:8751 Q07002 2678 CDK19 HGNC:19338 Q9BWU1 2679 CDK20 HGNC:21420 Q8IZL9 2680 CDKAL1 HGNC:21050 Q5VV42 2681 CDKL1 HGNC:1781 Q00532 2682 CDKL2 HGNC:1782 Q92772...
277 KB (17 words) - 18:34, 6 October 2024
differences in allelic frequencies between these populations. Genes such as CDKAL1, IGF2BP2, CDKN2A/CDKN2B, HHEX, SLC30A8, and KCNJ11 have shown risk alleles...
14 KB (1,514 words) - 14:40, 6 September 2024
KCNQ1, HNF1A, HNF1B MC4R, GIPR, HNF4A, MTNR1B, PPARG, ZBED3, SLC30A8, CDKAL1, GLIS3, GCK, GCKR, among others.KCNJ11 (potassium inwardly rectifying channel...
19 KB (2,339 words) - 07:33, 22 June 2024
most important common known genetic risk factor known, and variants in the CDKAL1 and other genes linked to insulin response and both increased and decreasednT2D...
103 KB (12,457 words) - 23:46, 12 June 2024
application of studying this specific MTTase is that it is encoded by the gene CDKAL1 in humans, which is known to increase the reduction of insulin secretion...
10 KB (1,219 words) - 08:51, 18 August 2023
Fujimura A, et al. (September 2011). "Deficit of tRNA(Lys) modification by Cdkal1 causes the development of type 2 diabetes in mice". The Journal of Clinical...
55 KB (6,104 words) - 00:18, 16 September 2024