Colony stimulating factor 1 receptor (redirect from CSF1R)
Colony stimulating factor 1 receptor (CSF1R), also known as macrophage colony-stimulating factor receptor (M-CSFR), and CD115 (Cluster of Differentiation...
44 KB (4,593 words) - 17:52, 18 April 2024
high levels of its receptor CSF1R in the placental trophoblast. Studies have shown that activation of trophoblastic CSF1R by local high levels of CSF-1...
17 KB (2,101 words) - 11:11, 21 December 2023
to CSF1R expressed on macrophages and inhibits the binding of colony-stimulating factor-1 (CSF-1) to CSF1R. This prevents CSF1R activation and CSF1R-mediated...
8 KB (697 words) - 19:21, 4 October 2023
Emmanuelle; Delord, Jean-Pierre; Blay, Jean-Yves; Rüttinger, Dominik (2015). "CSF1R inhibition with emactuzumab in locally advanced diffuse-type tenosynovial...
96 KB (467 words) - 19:33, 6 August 2024
known to follow an autosomal dominant pattern through a mutation in the CSF1R gene. The signs and symptoms that are present vary with each individual...
35 KB (3,951 words) - 16:14, 5 April 2024
therapy Chemotherapy Pexidartinib, a drug that targets a mutation in the CSF1R pathway and has shown sustained, complete response in limited use. Radiation...
22 KB (2,228 words) - 19:53, 23 August 2024
stimulating factor 1. This causes colony-stimulating factor-1 receptor (CSF1R) cells to accumulate in the joint tissue. TGCT can be diagnosed by magnetic...
30 KB (2,260 words) - 10:19, 10 September 2024
(October 2022). "Discovery of vimseltinib (DCC-3014), a highly selective CSF1R switch-control kinase inhibitor, in clinical development for the treatment...
3 KB (92 words) - 04:33, 16 September 2024
most families is mutation in the colony stimulating factor 1 receptor (CSF1R), a growth factor for microglia and monocyte/macrophages, suggesting that...
18 KB (2,136 words) - 01:58, 27 March 2024
Thuwajit, Chanitra; Chandhanayingyong, Chandhanarat (2 December 2022). "Novel CSF1R-positive tenosynovial giant cell tumor cell lines and their pexidartinib...
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IL-20Rα/IL-10Rβ heterodimer) Interleukin 32 Interleukin 34 (signals through M-CSFR/CSF1R) Interleukin 35 Unsorted: Efavaleukin alfa Efineptakin alfa...
22 KB (1,789 words) - 04:29, 16 July 2024
a small molecule inhibitor targeting multiple tyrosine kinases such as CSF1R, ABL, c-KIT, FLT3, and PDGFR-β. Specifically, it is used for chronic myelogenous...
71 KB (6,702 words) - 05:32, 9 August 2024
is also regulated by activation of colony stimulating factor 1 receptor (CSF1R). Menopause-associated increase production of TNF-α stimulates stromal cells...
124 KB (13,985 words) - 06:08, 25 September 2024
CEACAM5 CEACAM6 CEACAM8 CHL1 CILP CNTFR CNTN1 CNTN2 CNTN3 CNTN4 CNTN5 CNTN6 CSF1R DSCAM DSCAML1 EMB F11R FAIM3 FCAR FCER1A FCGR1A FCGR2A FCGR2B FCGR2C FCGR3A...
6 KB (493 words) - 18:09, 13 July 2024
effect. CSF1R inhibitors have been developed as a potential route to reduce the presence of TAMs in the tumor microenvironment. As of 2017, CSF1R inhibitors...
22 KB (2,507 words) - 23:16, 25 July 2024
"Sulfatinib, a novel multi-targeted tyrosine kinase inhibitor of FGFR1, CSF1R, and VEGFR1-3, suppresses osteosarcoma proliferation and invasion via dual...
5 KB (229 words) - 06:02, 5 July 2024
IL-20Rα/IL-10Rβ heterodimer) Interleukin 32 Interleukin 34 (signals through M-CSFR/CSF1R) Interleukin 35 Unsorted: Efavaleukin alfa Efineptakin alfa...
43 KB (3,661 words) - 19:54, 27 August 2024
class of receptor tyrosine kinases. It includes PDGFRα, PDGFRβ, C-KIT, CSF1R, and FLT3. Abu-Duhier FM, Goodeve AC, Care RS, et al. (February 2003). "Mutational...
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macrophage developmental arrest underlies depletion of microglia and reveals Csf1r-independent metaphocytes". eLife. 9: e53403. doi:10.7554/eLife.53403. ISSN 2050-084X...
3 KB (276 words) - 06:17, 15 November 2023
Meyer MA, Nywening TM, West BL, Luo J, et al. (September 2014). "CSF1/CSF1R blockade reprograms tumor-infiltrating macrophages and improves response...
92 KB (10,131 words) - 14:36, 2 September 2024
IL-20Rα/IL-10Rβ heterodimer) Interleukin 32 Interleukin 34 (signals through M-CSFR/CSF1R) Interleukin 35 Unsorted: Efavaleukin alfa Efineptakin alfa...
35 KB (2,793 words) - 23:27, 30 September 2024
IL-20Rα/IL-10Rβ heterodimer) Interleukin 32 Interleukin 34 (signals through M-CSFR/CSF1R) Interleukin 35 Unsorted: Efavaleukin alfa Efineptakin alfa...
16 KB (1,451 words) - 18:24, 2 August 2024
IL-20Rα/IL-10Rβ heterodimer) Interleukin 32 Interleukin 34 (signals through M-CSFR/CSF1R) Interleukin 35 Unsorted: Efavaleukin alfa Efineptakin alfa...
12 KB (877 words) - 03:57, 17 September 2024
IL-20Rα/IL-10Rβ heterodimer) Interleukin 32 Interleukin 34 (signals through M-CSFR/CSF1R) Interleukin 35 Unsorted: Efavaleukin alfa Efineptakin alfa...
14 KB (1,037 words) - 22:20, 19 September 2024
IL-20Rα/IL-10Rβ heterodimer) Interleukin 32 Interleukin 34 (signals through M-CSFR/CSF1R) Interleukin 35 Unsorted: Efavaleukin alfa Efineptakin alfa...
22 KB (2,581 words) - 20:03, 21 June 2024
IL-20Rα/IL-10Rβ heterodimer) Interleukin 32 Interleukin 34 (signals through M-CSFR/CSF1R) Interleukin 35 Unsorted: Efavaleukin alfa Efineptakin alfa...
17 KB (1,245 words) - 14:04, 2 September 2024
IL-20Rα/IL-10Rβ heterodimer) Interleukin 32 Interleukin 34 (signals through M-CSFR/CSF1R) Interleukin 35 Unsorted: Efavaleukin alfa Efineptakin alfa...
49 KB (6,005 words) - 16:30, 10 June 2024
progenitor cells require activation colony stimulating factor 1 receptor (CSF1R) for migration into the brain and differentiation into microglia. Additionally...
49 KB (5,780 words) - 11:15, 21 September 2024
ERBB3 ERBB4 Insulin receptor family IGF1R INSR INSRR PDGF receptor family CSF1R FLT3 KIT PDGFR (PDGFRA PDGFRB) FGF receptor family FGFR1 FGFR2 FGFR3 FGFR4...
9 KB (974 words) - 14:46, 22 June 2024
IL1R2 IL18R / IL18R1 IL 17 family IL17 IL17RA IL17RB IL17RC IL17RD IL17RE Enzyme-linked receptor Tyr CSF1R KIT Ser/Thr: TGF-beta TGFBR1 TGFBR2 family...
6 KB (442 words) - 05:35, 18 May 2024