Cytochrome P450 1B1 is an enzyme that in humans is encoded by the CYP1B1 gene. CYP1B1 belongs to the cytochrome P450 superfamily of enzymes. The cytochrome...
8 KB (1,111 words) - 18:29, 6 November 2023
the Prevention and Treatment of Cancer: Association of Cytochrome P450 CYP1B1 With the Role of Fruit and Fruit Extracts". Integrative Cancer Therapies...
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detoxification enzymes cytochrome P450 1A1 (CYP1A1) and cytochrome P450 1B1 (CYP1B1) are both protective and necessary for benzo[a]pyrene toxicity. Experiments...
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pressure (IOP). EyeRounds.org. September 17, 2008. 231300 137750; MYOC 137750; CYP1B1 Juvenile Glaucoma at eMedicine on eMedicine Glaucoma for Children on AAPOS...
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and free radicals. CYP1B1 can be induced by E2. ERα, after binding to estradiol, interacts with the CYP1B1 ERE to stimulate CYP1B1 expression. Thus, although...
14 KB (1,786 words) - 11:40, 10 March 2023
independently damage DNA. Enzymes in the cytochrome family (CYP1A1, CYP1A2, CYP1B1) metabolize PAHs to diol epoxides. PAH exposure can increase production...
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the liver enzyme CYP1A2 and to a lesser extent by CYP1A1, CYP2C19, and CYP1B1. For both research and clinical purposes, melatonin levels in humans can...
65 KB (6,956 words) - 23:32, 30 June 2024
Benzo[a]pyrene in Cyp1 knockout mouse lines: CYP1A1 important in detoxication, CYP1B1 metabolism required for immune damage independent of total-body burden and...
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and primary congenital glaucoma, which is associated with mutations in CYP1B1 or LTBP2. They are inherited in an autosomal recessive fashion. Axenfeld-Rieger...
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Phase I and Phase II metabolizing enzymes consisting of CYP1A1, CYP1A2, CYP1B1, NQO1, ALDH3A1, UGT1A2 and GSTA1. Presumably, vertebrates have this function...
52 KB (5,968 words) - 15:15, 4 June 2024
The isoform of the cytochrome P450 protein, 1B1 (CYP1B1) has shown interaction with myocilin. CYP1B1 is also found in several structures so the eye including...
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oxidative phase I enzymes and conjugative phase II enzymes, e.g. CYP1A2, CYP1B1, CYP2S1, CYP2A5, ALDH3, GSTA1, UGT1A1, UGT1A6, UGT1A7 and NQO1. This is...
86 KB (10,673 words) - 15:39, 23 June 2024
(2005). "Enzymatic Analysis of cDNA-Expressed Human CYP1A1, CYP1A2, and CYP1B1 With 7-Ethoxyresorufin as Substrate". In Phillips, I.R.; Shephard, E.A....
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HGNC:2584 Q9NQC7 3872 CYP1A1 HGNC:2595 P04798 3873 CYP1A2 HGNC:2596 P05177 3874 CYP1B1 HGNC:2597 Q16678 3875 CYP2A6 HGNC:2610 P11509 3876 CYP2A7 HGNC:2611 P20853...
277 KB (17 words) - 23:17, 27 April 2024
benzo[a]pyrene in Cyp1 knockout mouse lines: CYP1A1 important in detoxication, CYP1B1 metabolism required for immune damage independent of total-body burden and...
22 KB (2,409 words) - 21:42, 4 April 2024
wort, a common herbal remedy induces CYP3A4, but also inhibits CYP1A1, CYP1B1. Tobacco smoking induces CYP1A2 (example CYP1A2 substrates are clozapine...
42 KB (4,485 words) - 22:27, 17 July 2024
Alleyne, Angela T.; Bideau, Virgil S. (13 April 2019). "Haplotypes of CYP1B1 and CCDC57 genes in an Afro-Caribbean female population with uterine leiomyoma"...
145 KB (15,475 words) - 01:16, 2 July 2024
Benzo[a]pyrene in Cyp1 Knockout Mouse Lines: CYP1A1 Important in Detoxication, CYP1B1 Metabolism Required for Immune Damage Independent of Total-Body Burden and...
16 KB (1,494 words) - 08:30, 24 January 2024
include SOCS2 (i.e. suppressor of cytokine signaling 2), CYP1A1, CYP1A2, CYP1B1, glutathione S-transferase Ya subunit, quinone oxidoreductase, UDP-glucuronosyltransferase...
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400 families and this has helped in revealing 15 mutations in the gene CYP1B1, with mutation R368H being the most common one. The research has also recorded...
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bacterial or mammalian cytochrome P450 monooxygenase (Cyp1a1, Cyp1a2, or Cyp1b1 in mice; see CYP450 §§ CYP families in humans and P450s in other species)...
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Chakrabarti S (2011). "Primary Congenital Glaucoma and the Involvement of CYP1B1". Middle East Afr J Ophthalmol. 18 (1): 7–16. doi:10.4103/0974-9233.75878...
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of estrogens and/or carcinogens (Cytochrome P450, family 1, member A1, CYP1B1, CYP17A1, CYP19, Catechol-O-methyltransferase, N-acetyltransferase 2, Glutathione...
93 KB (10,786 words) - 06:34, 19 May 2024
Inhibitors Suppress Aryl Hydrocarbon Receptor-Mediated Activation of CYP1A1 and CYP1B1 Transcription and DNA Adduct Formation". Cancer Prevention Research. 1 (6):...
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5(S)-HpETE to 5-oxo-ETE by cytochrome P450 (CYP) enzymes such as CYP1A1, CYP1A2, CYP1B1, and CYP2S1; b) conversion of 5-HETE to 5-oxo-ETE non-enzymatically by heme...
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by the action of cytochrome P450 (CYP) enzymes such as CYP1A1, CYP1A2, CYP1B1, and CYP2S1. from 5(S)-HETE (and probably 5(R)-HETE) by the non-enzymatic...
34 KB (4,353 words) - 15:28, 26 February 2024
excellent CYP1A1 substrate, but is also a very good substrate for CYP1A2 and CYP1B1. The mono- and di-hydroxylated metabolites of FICZ are subject to further...
39 KB (4,634 words) - 07:07, 3 June 2024
CYP2J2. Metabolized by cytochrome P450 (CYP) enzymes such as CYP1A1, CYP1A2, CYP1B1, and CYP2S1 to 15-oxo-ETE. Metabolized in skin epidermis by epidermis-type...
67 KB (7,341 words) - 20:23, 5 April 2024
8-tetrachlorodibenzo-p-dioxin (TCDD) and benz(a)anthracene (BA) of cytochrome P4501B1 (CYP1B1) in mouse embryo fibroblasts (C3H10T1/2 cells)". Mol. Cell. Biochem. 198...
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congenital; 231300; CYP1B1 Glaucoma, primary open angle, adult-onset; 137760; CYP1B1 Glaucoma, primary open angle, juvenile-onset; 137750; CYP1B1 Glioblastoma...
234 KB (18,877 words) - 15:43, 9 May 2024