Cytochrome P450 2J2 (CYP2J2) is a protein that in humans is encoded by the CYP2J2 gene. CYP2J2 is a member of the cytochrome P450 superfamily of enzymes...

themselves. Some albendazole is also converted to hydroxyalbendazole, mainly by CYP2J2. For systemic parasites, albendazole acts as a prodrug, while albendazole...

animals and to a lesser extent in humans. CBG is metabolized in the liver by CYP2J2, similarly to other cannabinoids as well as endocannabinoids. CBG is a highly...

Bioavailability 80–100%; Cmax = 2–4 hours (10 mg oral) Metabolism CYP3A4, CYP2J2 and CYP-independent mechanisms Elimination half-life 5–9 hours in healthy...

within the CYP3A sub family, CYP3A4; in humans, CYP2C8, CYP2C9, CYP2C19, CYP2J2, and possibly CYP2S1 isoforms are the main producers of EETs although CYP2C9...

epoxygenases, CYP1A1, CYP1A2, CYP2C8, CYP2C9, CYP2C18, CYP2C19, CYP2E1, CYP2J2, and CYP2S1 metabolize arachidonic acid to the non-classic epoxyeicosatrienoic...

epoxyeicosatetraenoic acids (also termed EEQs). Along with CYP2C19, CYP2C8, CYP2C9, CYP2J2, and possibly CYP2S1 are the main producers of EETs and, very likely EEQs...

A0A087X1C5 3882 CYP2E1 HGNC:2631 P05181 3883 CYP2F1 HGNC:2632 P24903 3884 CYP2J2 HGNC:2634 P51589 3885 CYP2R1 HGNC:20580 Q6VVX0 3886 CYP2S1 HGNC:15654 Q96SQ9...

Pharmacokinetic data Protein binding 94–97% Metabolism Hepatic (CYP3A4, CYP3A5, CYP2J2) Metabolites N-Desmethyl-pimavanserin Elimination half-life Pimavanserin:...

Bioavailability ~100% Protein binding ≥99% Metabolism hepatic (CYP3A4 and CYP2J2) Elimination half-life 5–13 days Excretion feces (58%), urine (25%) Identifiers...

Bioavailability 94% Protein binding 95% Metabolism CYP1A1, CYP3A4, CYP2C8, CYP2J2 Metabolites N-desmethylriociguat (active), glucuronide (inactive) Elimination...

products that act as signaling molecules. It along with CYP2C8, CYP2C19, CYP2J2, and possibly CYP2S1 are the principle enzymes which metabolizes 1) arachidonic...

epoxydocosapentaenoic acids (i.e. EDPs). CYP2C8, CYP2C9, CYP2C18, CYP2C19, and CYP2J2 metabolize endogenous PUFAs to signaling molecules: they metabolize AA to...

unchanged drug & 18% as N-desmethyl metabolite) CYP3A4 CYP2C8 CYP2C19 CYP2D6 CYP2J2 ? Milnacipran 85-90% 6-8 (L-isomer), 8-10 (D-isomer) 400 L ? 2–4 hr 13%...

PUFAs include CYP1A1, CYP1A2, CYP2C8, CYP2C9, CYP2C18, CYP2C19, CYP2E1, CYP2J2, CYP2S1, CYP3A4, CYP4F2, CYP4F3A, CYP4F3B, CYP4A11, CYP4F8, and CYP4F12...

within the CYP3A subfamily, CYP3A4. In humans, CYP2C8, CYP2C9, CYP2C19, CYP2J2, and possibly CYP2S1 isoforms appear to be the principal epoxygenases responsible...

CYP3A4. In humans, CYP1A1, CYP1A2, CYP2C8, CYP2C9, CYP2C18, CYP2C19, CYP2E1, CYP2J2, CYP3A4, and CYP2S1 metabolize EPA to EEQs, in most cases forming principally...

Following proteins became known as potential direct binders of PTGIS: CYP2J2, GST, GSTA1, GLRX3, AKR1A1. Protein–protein and protein-peptide interactions...

epoxyeicosatetraenoic acids (also termed EEQs). Along with CYP2C8, CYP2C9, CYP2C19, CYP2J2, and possibly CYP2S1 are the main producers of EETs and, very likely, EEQs...

amounts of 20-HETE, and, in the case of the sheep enzyme, 18-HETE; human CYP2J2, however, is an epoxygenase, metabolizing arachidonic acid to epoxide products...

and edoxaban. Rivaroxaban Apixaban Edoxaban Metabolism CYP3A4/5 (major), CYP2J2 (minor) CYP3A4 (major), CYP1A2, 2C8, 2C19, 2J2 (all minor) CYP34A (major)...

more potent than the CYP450 epoxygenase (e.g. CYP2C8, CYP2C9, CYP2C19, CYP2J2, and CYP2S1)-formed epoxides of arachidonic acid (termed EETs) in decreasing...

epoxyeicosatetraenoic acids (also termed EEQs). While CYP2C19, CYP2C8, CYP2C9, CYP2J2, and possibly CYP2S1 are the main producers of EETs and, very likely EEQs...

by a hydroperoxide isomerase activity, possibly a cytochrome P450, i.e. CYP2J2. Metabolized by cytochrome P450 (CYP) enzymes such as CYP1A1, CYP1A2, CYP1B1...