Cytochrome P450 4F12 is a protein that in humans is encoded by the CYP4F12 gene. This gene encodes a member of the cytochrome P450 superfamily of enzymes...

Q08477 3898 CYP4F8 HGNC:2648 P98187 3899 CYP4F11 HGNC:13265 Q9HBI6 3900 CYP4F12 HGNC:18857 Q9HCS2 3901 CYP4F22 HGNC:26820 Q6NT55 3902 CYP4V2 HGNC:23198...

including human, tissues. The same CYPs but also CYP4A1, CYP4F8, and CYP4F12 metabolize eicosapentaenoic acid to five epoxide epoxyeicosatetraenoic...

EETs to 20-hydroxy-EETs, and lipoxins to 20-hydroxy products. CYP4F8 and CYP4F12 metabolize PUFAs to signaling molecules: they metabolizes EPA to EEQs and...

ability to form epoxides, of CYP4F8 is very similar to that of CYP4F12. However, it and CYP4F12 are not regarded as being major contributors in forming the...

CYP2J2, CYP2S1, CYP3A4, CYP4F2, CYP4F3A, CYP4F3B, CYP4A11, CYP4F8, and CYP4F12. CYP2C8 and CYP2C9 form particularly large amounts of superoxide anion...

CYP2E1, CYP4A11, CYP4F8, and CYP4F12 also metabolize DHA to EDPs. CYP2C8, CYP2C18, CYP2E1, CYP2J2, VYP4A11, CYP4F8, and CYP4F12 preferentially attack the...

to contract coronary arteries.) 7) CYP4A11, CYP4F2, CYP4F3B, CYP4F11, CYP4F12, CYP4V2, CYP2U1, and possibly CYP4Z1 metabolize arachidonic acid to...

amounts of 17S,18R-EEQ. In addition to the cited CYP's, CYP4A11, CYP4F8, CYP4F12, CYP1A1, CYP1A2, and CYP2E1, which are classified as CYP monooxygenase...

producers of EETs although CYP2C9, CYP2C18, CYP3A4, CYP4A11, CYP4F8, and CYP4F12 are capable of producing the EETs and may do so in certain tissues. The...

anti-inflammatory leukotrienes, modulating their biological activities. CYP4F8 and CYP4F12 are involved in the metabolism of prostaglandins, endoperoxides, and arachidonic...

isomers). CYP4A11 does not convert arachidonic acid to epoxides. CYP4F8 and CYP4F12 likewise possess both monooxygenase activity for arachidonic acid and epoxygenase...