Celastrol (tripterine) is a chemical compound isolated from the root extracts of Tripterygium wilfordii (Thunder god vine) and Tripterygium regelii (Regel's...
12 KB (1,174 words) - 07:17, 19 May 2024
wilfordii extract is a useful remedy for postmenopausal rheumatoid arthritis. Celastrol, a pentacyclic triterpenoid, and triptolide, a diterpene triepoxide, are...
11 KB (1,165 words) - 12:58, 27 June 2024
methide is the mechanistic basis of many phenolic anti-cancer drugs. Celastrol is a triterpenoid quinone methide isolated from Tripterygium wilfordii...
18 KB (1,865 words) - 05:04, 27 December 2023
02.012. PMID 24680370. Yang H, Chen D, Cui QC, Yuan X, Dou QP (2006). "Celastrol, a triterpene extracted from the Chinese "Thunder of God Vine," is a potent...
6 KB (166 words) - 21:07, 28 August 2023
BCR-Abl's activity by blocking the active kinase domain (Fava et al., 2011). Celastrol is a compound extracted from Tripterygium wilfordii that has anti-cancer...
25 KB (3,160 words) - 20:16, 30 November 2023
are several ligands that directly bind NR4A1, including cytosporone B, celastrol, and certain polyunsaturated fatty acids. These NR4A1 ligands bind at...
21 KB (2,530 words) - 02:53, 28 March 2024
inhibition of Th17/Th22 pathway in 2D and 3D human models of psoriasis by Celastrol enriched plant cell culture extract". Journal of the European Academy...
10 KB (1,193 words) - 09:35, 19 March 2024
(2021). "The genome of Tripterygium wilfordii and characterization of the celastrol biosynthesis pathway". Gigabyte. 2021: 1–30. doi:10.46471/gigabyte.14...
173 KB (10,364 words) - 15:01, 25 September 2024
Liu X, Guo D (11 July 2013). "ER stress-mediated apoptosis induced by celastrol in cancer cells and important role of glycogen synthase kinase-3β in the...
25 KB (3,183 words) - 04:46, 19 October 2022