Cobalt chelatase (EC 6.6.1.2) is an enzyme that catalyzes the chemical reaction ATP + hydrogenobyrinic acid a,c-diamide + Co2+ + H2O ⇌ {\displaystyle \rightleftharpoons...
6 KB (617 words) - 13:35, 26 August 2023
tetrapyrrole macrocycle. Several families of chelatase are known including cobalt chelatase, magnesium chelatase, and ferrochelatase. Nickel insertion into...
3 KB (249 words) - 22:22, 20 June 2023
Sirohydrochlorin cobaltochelatase (redirect from Cobalt-sirohydrochlorin cobalt-lyase (sirohydrochlorin-forming))
is cobalt-sirohydrochlorin cobalt-lyase (sirohydrochlorin-forming). Other names in common use include CbiK, CbiX, CbiXS, anaerobic cobalt chelatase, cobaltochelatase...
4 KB (334 words) - 15:50, 26 August 2023
the metal cation is inserted into protoporphyrin IX by enzymes called chelatases. For example, ferrochelatase converts the compound into heme B (i.e. Fe-protoporphyrin...
14 KB (1,408 words) - 18:15, 22 October 2024
+ 2 phosphate + 2 glutamic acid Cobalt(II) insertion into the macrocycle is catalysed by the enzyme Cobalt chelatase (CobNST): hydrogenobyrinic acid a...
36 KB (3,654 words) - 20:12, 4 September 2024
the metal in the N42- "pocket." In nature, the insertion is mediated by chelatase enzymes. The insertion of a metal proceeds by the intermediacy of a "sitting...
13 KB (1,274 words) - 06:47, 22 June 2024
tetrapyrrole is catalysed in reaction EC 4.99.1.11 by the same chelatase, CbiX, which inserts cobalt in the biosynthesis of cobalamin, here giving nickel(II)-sirohydrochlorin...
10 KB (903 words) - 19:19, 23 September 2023