In organic synthesis, cyanation is the attachment or substitution of a cyanide group on various substrates. Such transformations are high-value because...

can perform unique transformations on benzene, such as halogenation, cyanation, trifluoromethylation, and hydroxylation. The reaction was discovered...

(toxic) is largely not encouraged, for this reason other less dangerous cyanation reagents are sought out. In situ formation of HCN can be sourced using...

cyanide. Lithium cyanide can be used as a reagent for organic compound cyanation. RX + LiCN → RCN + LiX J. A. Lely, J. M. Bijvoet (1942), "The Crystal...

Chlorination Clusterification Comproportionation C–C coupling C–H activation Cyanation Cyclometalation Decarbonylation Decarboxylation Dehydration Dehalogenation...

pesticides, such as mustard oil. Illustrative of its reactivity is its cyanation to allyl cyanide (CH2=CHCH2CN). Being a reactive alkyl halide, it undergoes...

Yan; Yang, Haitao; Cheng, Jiang (2014). "A copper-mediated oxidative N-cyanation reaction". Chemical Communications. 50 (61): 8412–8415. doi:10.1039/c4cc03439b...

water, but is stable in aqueous mineral acid. Synthesis of DDQ involves cyanation of chloranil. J. Thiele and F. Günther first reported a 6-step preparation...

Searle AD (2017). "An Evaluation of Multiple Catalytic Systems for the Cyanation of 2,3-Dichlorobenzoyl Chloride: Application to the Synthesis of Lamotrigine"...

acrylic acid followed by reacidification. Another synthesis involves cyanation of ethylene chlorohydrin followed by hydrolysis of the resulting nitrile...

exhibits some biological activity. It is prepared from benzaldehyde by amino cyanation (Strecker synthesis). It can also be prepared from glyoxal and by reductive...

nanoparticles using Plantago asiatica leaf extract and their application for the cyanation of aldehydes using K4Fe(CN)6". Journal of Colloid and Interface Science...

[11C]LY2795050 for Preclinical and Clinical PET Imaging Using Cu(II)-Mediated Cyanation," ACS Med. Chem. Lett. 2018, 9, 1274–1279. Malapit, C. A.; Bour, J. R...

"Ethyl Cyanoacetate: A New Cyanating Agent for the Palladium-Catalyzed Cyanation of Aryl Halides". Org. Lett. 14 (14): 3644–3647. doi:10.1021/ol3014914...

Theunissen, Alexandre Pradal, Gwilherm Evano (2016). "Copper-catalyzed Cyanation of Alkenyl Iodides". Org. Synth. 93: 163. doi:10.15227/orgsyn.093.0163...

cancer. 4-(trifluoromethyl)benzonitrile, produced by the Nickel catalyzed cyanation of 4-chlorobenzotrifluoride is a precursor for the antidepressant Fluvoxamine...

to the isomeric aminoiminosuccinonitrile (AISN). It can be prepared by cyanation of aminomalonitrile. Diaminomaleonitrile has been proposed since the 1960s...

reactions, to affect the direct regioselective arylation, alkenylation, cyanation and further functionalisation of C-H positions in diverse scaffolds. Micklefield's...

isothiocyanate derivatives. Some organic thiocyanates are generated by cyanation of some organosulfur compounds. Sulfenyl thiosulfates (RSSO3−) react with...

Hooker, Jacob M. (2015). "Virtually Instantaneous, Room-Temperature [11C]-Cyanation Using Biaryl Phosphine Pd(0) Complexes". Journal of the American Chemical...

S.; Scott, Peter J. H. (February 27, 2018). "Copper(II)-Mediated [11C]Cyanation of Arylboronic Acids and Arylstannanes". Organic Letters. 20 (6): 1530–1533...