G1/S-specific cyclin-D2 is a protein that in humans is encoded by the CCND2 gene. The protein encoded by this gene belongs to the highly conserved cyclin family...

proteins have been identified. The three homologues, called cyclin D1, cyclin D2, and cyclin D3 are expressed in most proliferating cells and the relative...

Dopamine receptor D2, a protein Levuglandin D2 Prostaglandin D2 receptor, a G-protein coupled receptor Resolvin D2 Cyclin D2 (CCND2) Vitamin D2, or ergocalciferol...

of a protein kinase, cyclin-dependent kinase (CDK), with a regulatory subunit, cyclin. Once cyclin-dependent kinases bind to cyclin, the formed complex...

Cyclin-dependent kinase 4 also known as cell division protein kinase 4 is an enzyme that in humans is encoded by the CDK4 gene. CDK4 is a member of the...

Brooks EE, Milner PG (April 1996). "Functional analysis of the human cyclin D2 and cyclin D3 promoters". The Journal of Biological Chemistry. 271 (15): 9090–9099...

phosphorylation, and inositol phosphate formation. Zymosan A also raises cyclin D2 levels, suggesting a role for the latter in macrophage activation besides...

over-expression of cyclin D2, cyclin D3 or cyclin E, which also lead to cell cycle hyperactivity and have a similar prognosis to the main cyclin-D1 variant of...

shortened. This has been attributed to high mRNA levels of G1-related Cyclin D2 and Cdk4 genes and low levels of cell cycle regulatory proteins that inhibit...

encoded by the CDK6 gene. It is regulated by cyclins, more specifically by Cyclin D proteins and Cyclin-dependent kinase inhibitor proteins. The protein...

cyclin, cyclin D1. Myc also regulates expression of a wide variety of pro-proliferative and pro-growth genes, including some induction of cyclin D2 and...

arrest is linked with cyclin D1 and cyclin D2 suppression in mammals. It was detected that human FOXO1 is linked with the cyclin D1 promoter using chromatin...

Especially the D2 receptor is considered a major hub within the GPCR heteromer network. Protomers consist of Isoreceptors D1–D2 D1–D3 D2–D3 D2–D4 D2–D5 Non-isoreceptors...

p16 (also known as p16INK4a, cyclin-dependent kinase inhibitor 2A, CDKN2A, multiple tumor suppressor 1 and numerous other synonyms), is a protein that...

controlled by cyclin and cyclin-dependent kinases. The progression of interphase is the result of the increased amount of cyclin. As the amount of cyclin increases...

Other reported downstream ALK targets include FOXO3a, CDKN1B/p27kip, cyclin D2, NIPA, RAC1, CDC42, p130CAS, SHP1, and PIKFYVE. Phosphorylated ALK activates...

with the role of Pitx2 in regulating the growth-regulating genes cyclin D2, cyclin D1, and C-Myc. In renal cancer, Pitx2 regulates expression of ABCB1...

protein phosphorylation. Furthermore, Runx2 controls the gene expression of cyclin D2, D3, and the CDK inhibitor p21(cip1) in hematopoietic cells. It has been...

Berger R, Bernard O, Fioretos T, Johansson B (July 2006). "Deregulation of cyclin D2 by juxtaposition with T-cell receptor alpha/delta locus in t(12;14)(p13;q11)-positive...

regulate ethanol-induced neuronal cell death through BCL2 protein and cyclin D2". The Journal of Biological Chemistry. 286 (43): 37347–57. doi:10.1074/jbc...

2013). "Control of asymmetry distribution and the differentiation fate of Cyclin D2 in the nerve trunk cell". Seitai No Kagaku. 64 (6). The Ichiro Kanehara...

Cyclin-O is a protein that in humans is encoded by the CCNO gene. Cyclin O has been shown to interact with RPA2 and PCNA. GRCm38: Ensembl release 89: ENSMUSG00000042417...

Argani P (December 2003). "DNA methylation of RASSF1A, HIN-1, RAR-beta, Cyclin D2 and Twist in in situ and invasive lobular breast carcinoma". International...

t(11:14)q13:q32) translocation, perhaps because the overexpression of cyclin D2 is weaker than Bcl2 overexpression in driving cells to accumulate and...

Cyclin-dependent kinase 4 inhibitor D is an enzyme that in humans is encoded by the CDKN2D gene. The protein encoded by this gene is a member of the INK4...

human Gli1 include regulators of the cell cycle and apoptosis such as cyclin D2 and plakoglobin respectively. Gli1 also upregulates FoxM1 in BCC. Gli1...

hepatocellular carcinoma cells, in part through direct downregulation of cyclin D2 and cyclin E2. miR-26a also directly suppresses expression of estrogen receptor...

separation. It also targets S and M-phase (S/M) cyclins for destruction, which inactivates S/M cyclin-dependent kinases (Cdks) and allows the cell to...

example of E2F-regulated genes repressed by pRb are cyclin E and cyclin A. Both of these cyclins are able to bind to Cdk2 and facilitate entry into the...

and GTF2H5/TTDA) form the core complex. The cyclin-activating kinase-subcomplex (CDK7, MAT1, and cyclin H) is linked to the core via the XPD protein...