Cyclotraxin B (CTX-B) is a small (1200 Da) cyclic peptide and highly potent (IC50 = 0.30 nM), selective, and non-competitive antagonist or negative allosteric...
5 KB (335 words) - 14:43, 16 July 2024
in that race was Bo Hamburger, although he was later acquitted because his B-sample was not conclusive. The U.S. Postal Service Pro Cycling Team, under...
31 KB (3,430 words) - 05:24, 28 August 2024
growth factor (PGF) Ripretinib Telbermin VEGF (A, B, C, D (FIGF)) Allosteric modulators: Cyclotraxin B Kinase inhibitors: Agerafenib Altiratinib Axitinib...
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tropoflavin) R13 (prodrug of tropoflavin) TDP6 Tropoflavin (7,8-DHF) ANA-12 Cyclotraxin B Gossypetin (3,5,7,8,3',4'-HHF) Fluoxetine Imipramine Ketamine (2R...
40 KB (4,319 words) - 02:54, 11 August 2024
1450–1455. doi:10.4187/respcare.03023. PMID 24782550. Brunton L, Knollman B, Hilal-Dandan R (26 October 2017). Goodman and Gilman's The Pharmacological...
34 KB (3,021 words) - 12:39, 5 August 2024
HER2 (redirect from ErbB-2 receptor)
erbB-2 is a protein that normally resides in the membranes of cells and is encoded by the ERBB2 gene. ERBB is abbreviated from erythroblastic oncogene B...
43 KB (4,651 words) - 13:41, 27 July 2024
PMID 19614649. S2CID 2655192. Zimmer BM, Berdel WE, Ludwig WD, Notter M, Reufi B, Thiel E (March 1993). "Fatal spleen rupture during induction chemotherapy...
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pathway as well as the PI3 kinase/AKT pathway, which in turn activates the NF-κB pathway. In cancer cells the HER2 protein can be expressed up to 100 times...
67 KB (5,977 words) - 19:32, 17 August 2024
Drugs.com. 2024. Retrieved 10 July 2024. Windisch M, Gschanes A, Hutter-Paier B (1998). "Neurotrophic activities and therapeutic experience with a brain derived...
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PMC 6541928. PMID 30449625. Mehanna H, Robinson M, Hartley A, Kong A, Foran B, Fulton-Lieuw T, et al. (January 2019). "Radiotherapy plus cisplatin or cetuximab...
26 KB (2,420 words) - 06:06, 17 August 2024
growth factor (PGF) Ripretinib Telbermin VEGF (A, B, C, D (FIGF)) Allosteric modulators: Cyclotraxin B Kinase inhibitors: Agerafenib Altiratinib Axitinib...
10 KB (579 words) - 06:46, 26 June 2024
The ErbB family of proteins contains four receptor tyrosine kinases, structurally related to the epidermal growth factor receptor (EGFR), its first discovered...
24 KB (2,736 words) - 00:12, 28 November 2023
PMID 2982726. S2CID 5825276. Jansen M, van Schaik FM, Ricker AT, Bullock B, Woods DE, Gabbay KH, et al. (1983). "Sequence of cDNA encoding human insulin-like...
35 KB (4,573 words) - 09:59, 28 August 2024
growth factor (PGF) Ripretinib Telbermin VEGF (A, B, C, D (FIGF)) Allosteric modulators: Cyclotraxin B Kinase inhibitors: Agerafenib Altiratinib Axitinib...
17 KB (1,489 words) - 05:47, 7 April 2024
growth factor (PGF) Ripretinib Telbermin VEGF (A, B, C, D (FIGF)) Allosteric modulators: Cyclotraxin B Kinase inhibitors: Agerafenib Altiratinib Axitinib...
10 KB (661 words) - 04:10, 26 June 2024
growth factor (PGF) Ripretinib Telbermin VEGF (A, B, C, D (FIGF)) Allosteric modulators: Cyclotraxin B Kinase inhibitors: Agerafenib Altiratinib Axitinib...
15 KB (975 words) - 03:53, 27 June 2024
CD004405.pub5. PMC 6491272. PMID 26362566. Roila F, Ballatori E, Ruggeri B, DeAngelis V (May 2000). "Dexamethasone alone or in combination with ondansetron...
68 KB (5,999 words) - 20:41, 31 August 2024
growth factor (PGF) Ripretinib Telbermin VEGF (A, B, C, D (FIGF)) Allosteric modulators: Cyclotraxin B Kinase inhibitors: Agerafenib Altiratinib Axitinib...
25 KB (2,086 words) - 02:24, 16 July 2024
growth factor (PGF) Ripretinib Telbermin VEGF (A, B, C, D (FIGF)) Allosteric modulators: Cyclotraxin B Kinase inhibitors: Agerafenib Altiratinib Axitinib...
14 KB (1,689 words) - 01:31, 19 August 2024
synthesis. Activates B-cells and NK cells. IL-3 – Stimulates production of all non-lymphoid cells. IL-4 – Growth factor for activated B cells, resting T cells...
10 KB (1,131 words) - 19:14, 31 March 2024
growth factor (PGF) Ripretinib Telbermin VEGF (A, B, C, D (FIGF)) Allosteric modulators: Cyclotraxin B Kinase inhibitors: Agerafenib Altiratinib Axitinib...
11 KB (934 words) - 23:22, 24 August 2024
has a molecular mass of 5808 Da. It is a heterodimer of an A-chain and a B-chain, which are linked together by disulfide bonds. Insulin's structure varies...
121 KB (13,799 words) - 18:32, 22 August 2024
2066–7. doi:10.1056/NEJMcibr0800272. PMID 18463385. Sliesoraitis S, Tawfik B (July 2011). "Bevacizumab-induced bowel perforation". The Journal of the American...
73 KB (6,440 words) - 02:59, 3 September 2024
Lin ZC, Churko JM, Ebert AD, Lan F, Diecke S, Huber B, Mordwinkin NM, Plews JR, Abilez OJ, Cui B, Gold JD, Wu JC (August 2014). "Chemically defined generation...
64 KB (7,427 words) - 21:08, 3 August 2024
Brain-derived neurotrophic factor (category TrkB agonists)
the TrkB tyrosine kinase receptor. BDNF acts on certain neurons of the central nervous system and the peripheral nervous system expressing TrkB, helping...
46 KB (5,344 words) - 03:26, 11 August 2024
TRAF6, which results in the release of nuclear factor κB (NF-κB) transcription activator. NF-κB regulates nuclear gene transcription to promote cell survival...
24 KB (2,872 words) - 06:27, 22 July 2024
Archived from the original on 3 July 2013. Retrieved 3 April 2013. Kasper B, Gruenwald V, Reichardt P, Bauer S, Rauch G, Limprecht R, et al. (May 2017)...
71 KB (6,702 words) - 05:32, 9 August 2024
family comprises five members: VEGF-A, placenta growth factor (PGF), VEGF-B, VEGF-C and VEGF-D. The latter members were discovered after VEGF-A; before...
40 KB (4,580 words) - 05:24, 3 June 2024
growth factor (PGF) Ripretinib Telbermin VEGF (A, B, C, D (FIGF)) Allosteric modulators: Cyclotraxin B Kinase inhibitors: Agerafenib Altiratinib Axitinib...
5 KB (412 words) - 23:17, 19 June 2023
7709–12. doi:10.1016/S0021-9258(19)38983-5. PMID 2186024. Custo S, Baron B, Felice A, Seria E (5 July 2022). "A comparative profile of total protein...
17 KB (1,708 words) - 13:56, 21 July 2024