DNA-binding proteins are proteins that have DNA-binding domains and thus have a specific or general affinity for single- or double-stranded DNA. Sequence-specific...
22 KB (2,637 words) - 15:36, 23 December 2024
Single-strand DNA-binding protein (SSB) is a protein found in Escherichia coli (E. coli) bacteria, that binds to single-stranded regions of deoxyribonucleic...
4 KB (425 words) - 03:32, 25 September 2024
Transactive response DNA binding protein 43 kDa (TAR DNA-binding protein 43 or TDP-43) is a protein that in humans is encoded by the TARDBP gene. TDP-43...
41 KB (4,646 words) - 22:19, 12 October 2024
A DNA-binding domain (DBD) is an independently folded protein domain that contains at least one structural motif that recognizes double- or single-stranded...
19 KB (2,167 words) - 16:54, 24 September 2024
Zinc finger (redirect from Zinc-containing DNA-binding motif)
of zinc fingers with DNA. The binding of zinc finger is found to be distinct from many other DNA-binding proteins that bind DNA through the 2-fold symmetry...
42 KB (4,879 words) - 13:27, 9 October 2024
Helicase-primase complex and a single-stranded DNA-binding protein. The human herpesvirus 1 (HHV-1) single-strand DNA-binding protein ICP8 is a 128kDa zinc metalloprotein...
10 KB (1,016 words) - 04:21, 25 August 2024
bacterial DNA binding proteins are a family of small, usually basic proteins of about 90 residues that bind DNA and are known as histone-like proteins. Since...
19 KB (2,263 words) - 01:58, 11 December 2023
Activator (genetics) (redirect from DNA Activation)
activators function by binding sequence-specifically to a regulatory DNA site located near a promoter and making protein–protein interactions with the...
17 KB (1,959 words) - 02:34, 31 December 2023
distinct group of DNA-binding proteins is the DNA-binding proteins that specifically bind single-stranded DNA. In humans, replication protein A is the best-understood...
166 KB (17,847 words) - 05:38, 10 January 2025
polymerase, and Single-strand DNA-binding protein) and with the DNA replication fork enhancing DNA-unwinding and DNA-replication. These results lead...
59 KB (7,322 words) - 18:02, 20 December 2024
Transcription factor (redirect from Sequence-specific DNA-binding factor)
sequence-specific DNA-binding factor) is a protein that controls the rate of transcription of genetic information from DNA to messenger RNA, by binding to a specific...
75 KB (8,343 words) - 18:14, 19 December 2024
DNA damage-binding protein or UV-DDB is a protein complex that is responsible for repair of UV-damaged DNA. This complex is composed of two protein subunits...
6 KB (654 words) - 23:59, 31 May 2022
will often protect that DNA from enzymatic cleavage. This makes it possible to locate a protein binding site on a particular DNA molecule. The method uses...
3 KB (362 words) - 10:16, 13 January 2024
Lac repressor (category Bacterial proteins)
The lac repressor (LacI) is a DNA-binding protein that inhibits the expression of genes coding for proteins involved in the metabolism of lactose in bacteria...
15 KB (1,690 words) - 08:19, 11 November 2024
Sex-determining region Y protein (SRY), or testis-determining factor (TDF), is a DNA-binding protein (also known as gene-regulatory protein/transcription factor)...
39 KB (4,858 words) - 19:27, 3 December 2024
The TATA-binding protein (TBP) is a general transcription factor that binds to a DNA sequence called the TATA box. This DNA sequence is found about 30...
28 KB (3,218 words) - 14:36, 18 March 2024
DnaA is a protein that activates initiation of DNA replication in bacteria. Based on the Replicon Model, a positively active initiator molecule contacts...
34 KB (4,283 words) - 16:08, 15 December 2024
Inhibitor of DNA-binding/differentiation proteins, also known as ID proteins comprise a family of proteins that heterodimerize with basic helix-loop-helix...
10 KB (1,201 words) - 07:56, 20 September 2024
Repressor (redirect from Repressor Protein)
a DNA- or RNA-binding protein that inhibits the expression of one or more genes by binding to the operator or associated silencers. A DNA-binding repressor...
13 KB (1,503 words) - 19:58, 1 January 2024
Lambda phage (redirect from Lambda DNA)
as the cI protein. It binds DNA in the helix-turn-helix binding motif. It regulates the transcription of the cI protein and the Cro protein. The life...
54 KB (5,955 words) - 15:02, 21 December 2024
Replication protein A (RPA) is the major protein that binds to single-stranded DNA (ssDNA) in eukaryotic cells. In vitro, RPA shows a much higher affinity...
7 KB (785 words) - 02:24, 4 January 2025
A binding protein is any protein that acts as an agent to bind two or more molecules together. Examples include: DNA-binding protein Single-strand binding...
2 KB (263 words) - 21:49, 28 December 2020
in the DNA. A Z-DNA high affinity binding protein, hZαADAR1, was used at varying concentrations to induce the transformation from B-DNA to Z-DNA. The smFRET...
34 KB (4,310 words) - 05:43, 18 September 2024
Nucleoid (section DNA supercoiling and gene expression)
DNA wrapped around an octameric complex of the histone proteins. Although bacteria do not have histones, they possess a group of DNA binding proteins...
151 KB (17,185 words) - 06:38, 8 August 2024
chromatin-binding proteins in eukaryotes. DamID identifies binding sites by expressing the proposed DNA-binding protein as a fusion protein with DNA methyltransferase...
18 KB (2,212 words) - 14:17, 26 April 2024
P53 (redirect from Protein P53)
Bliss T, et al. (July 1998). "DNA end-independent activation of DNA-PK mediated via association with the DNA-binding protein C1D". Genes & Development. 12...
127 KB (13,341 words) - 11:18, 23 December 2024
MECP2 (redirect from Methyl CpG binding protein 2)
CpG binding protein 2) is a gene that encodes the protein MECP2. MECP2 appears to be essential for the normal function of nerve cells. The protein seems...
28 KB (3,589 words) - 19:16, 7 December 2024
KS, Darst SA, Berman HM, Ebright RH (2004). "Catabolite activator protein: DNA binding and transcription activation". Curr. Opin. Struct. Biol. 14 (1):...
5 KB (579 words) - 19:37, 9 November 2024
"Characterization of DNA-binding and strand-exchange stimulation properties of y-RPA, a yeast single-strand-DNA-binding protein". Journal of Molecular...
121 KB (14,916 words) - 04:06, 3 January 2025
Replication protein A 70 kDa DNA-binding subunit is a protein that in humans is encoded by the RPA1 gene. Replication protein A1 has been shown to interact...
13 KB (1,549 words) - 16:10, 4 January 2024