• Thumbnail for Dopamine receptor D4
    Dopamine receptor D4 (redirect from DRD4)
    D2-like G protein-coupled receptor encoded by the DRD4 gene on chromosome 11 at 11p15.5. The structure of DRD4 has been reported in complex with the antipsychotic...
    36 KB (4,075 words) - 23:34, 2 October 2024
  • task" for an extended time. Genetic variants (such as the DRD4 7R allele, as well as others on DRD4 and DRD2) conferring susceptibility to ADHD are very frequent—implying...
    11 KB (1,305 words) - 07:49, 27 August 2024
  • risk-taking and the DRD4 gene in young males. Although studies support the link between novelty seeking and dopaminergic activity via DRD4, other studies do...
    9 KB (1,058 words) - 19:07, 31 October 2024
  • Thumbnail for Methamphetamine
    Nuclear membrane Plasma membrane Cav1.2 NMDAR AMPAR DRD1 DRD5 DRD2 DRD3 DRD4 Gs Gi/o AC cAMP cAMP PKA CaM CaMKII DARPP-32 PP1 PP2B CREB ΔFosB JunD c-Fos...
    156 KB (15,398 words) - 12:48, 28 October 2024
  • Thumbnail for Causes of mental disorders
    of dopamine receptor D4 (DRD4–7R) causes increased inhibitory effects induced by dopamine and is associated with ADHD. The DRD4 receptor is a G protein-coupled...
    65 KB (10,200 words) - 20:33, 29 October 2024
  • Thumbnail for Dopamine receptor
    Calleja and nucleus accumbens. D4 is encoded by the Dopamine receptor D4 gene (DRD4). The D4 receptor gene displays polymorphisms that differ in a variable number...
    50 KB (5,330 words) - 03:50, 17 June 2024
  • Thumbnail for Bipolar disorder
    is responsible for bipolar disorder in most cases. Polymorphisms in BDNF, DRD4, DAO, and TPH1 have been frequently associated with bipolar disorder and...
    157 KB (17,739 words) - 17:48, 28 October 2024
  • of dopamine receptor D4 (DRD4–7R) causes increased inhibitory effects induced by dopamine and is associated with ADHD. The DRD4 receptor is a G protein-coupled...
    260 KB (27,798 words) - 10:24, 1 November 2024
  • Thumbnail for Addiction
    Nuclear membrane Plasma membrane Cav1.2 NMDAR AMPAR DRD1 DRD5 DRD2 DRD3 DRD4 Gs Gi/o AC cAMP cAMP PKA CaM CaMKII DARPP-32 PP1 PP2B CREB ΔFosB JunD c-Fos...
    224 KB (25,904 words) - 13:11, 22 October 2024
  • Thumbnail for Amphetamine
    Nuclear membrane Plasma membrane Cav1.2 NMDAR AMPAR DRD1 DRD5 DRD2 DRD3 DRD4 Gs Gi/o AC cAMP cAMP PKA CaM CaMKII DARPP-32 PP1 PP2B CREB ΔFosB JunD c-Fos...
    274 KB (28,854 words) - 09:38, 23 October 2024
  • Thumbnail for Borderline personality disorder
    Among specific genetic variants under scrutiny as of 2012[update], the DRD4 7-repeat polymorphism (of the dopamine receptor D4) located on chromosome...
    185 KB (19,281 words) - 03:30, 30 October 2024
  • Thumbnail for Dopamine
    intracellular levels of cAMP by inhibiting adenylate cyclase. D3 DRD3 D4 DRD4 TAAR TAAR1 TAAR1 Gs-coupled. Gq-coupled. Increase intracellular levels of...
    139 KB (14,249 words) - 04:40, 28 September 2024
  • Thumbnail for Ornithology
    major) have been found to be linked with a gene orthologous to the human gene DRD4 (Dopamine receptor D4) which is known to be associated with novelty-seeking...
    80 KB (9,216 words) - 22:36, 9 October 2024
  • Thumbnail for Siberian Husky
    Husky". Federation Cynologique Internationale. Retrieved 24 January 2021. "DRD4 and TH gene polymorphisms are associated with activity, impulsivity and inattention...
    46 KB (4,961 words) - 23:20, 18 October 2024
  • Thumbnail for Altruism
    genes include OXTR (polymorphisms in the oxytocin receptor), CD38, COMT, DRD4, DRD5, IGF2, AVPR1A and GABRB2. It is theorized that some of these genes...
    92 KB (10,872 words) - 02:08, 1 November 2024
  • nucleotide polymorphism (SNP). It is located in the promoter region of the DRD4 gene. This gene codes for the dopamine receptor D4. Due to the dopamine hypothesis...
    3 KB (323 words) - 04:36, 10 March 2024
  • Thumbnail for Shyness
    shyness and aggression are related—through long and short forms of the gene DRD4, though considerably more research on this is needed. Further, it has been...
    46 KB (5,600 words) - 03:26, 19 July 2024
  • polymorphism (DRD4-7R) on the association between maternal sensitivity and externalizing behavior problems in 47 families. Children with the DRD4-7R allele...
    19 KB (2,268 words) - 18:04, 3 October 2023
  • Thumbnail for Thiethylperazine
    phenothiazine class. It is an antagonist of dopamine receptors (DRD1, DRD2, DRD4) as well as of 5-HT2A, 5-HT2C receptors, mAChRs (1 through 5), α1 adrenergic...
    8 KB (567 words) - 12:45, 5 August 2024
  • Thumbnail for MOS Technology Agnus
    RD7 DRD7 DRD7 DRD7 8 RD6 DRD6 DRD6 DRD6 9 RD5 DRD5 DRD5 DRD5 10 RD4 DRD4 DRD4 DRD4 11 RD3 DRD3 DRD3 DRD3 12 RD2 DRD2 DRD2 DRD2 13 RD1 DRD1 DRD1 DRD1 14...
    11 KB (703 words) - 02:00, 20 January 2024
  • Thumbnail for Adderall
    Nuclear membrane Plasma membrane Cav1.2 NMDAR AMPAR DRD1 DRD5 DRD2 DRD3 DRD4 Gs Gi/o AC cAMP cAMP PKA CaM CaMKII DARPP-32 PP1 PP2B CREB ΔFosB JunD c-Fos...
    58 KB (21,548 words) - 19:20, 8 October 2024
  • Thumbnail for Chromosome 11
    7-dehydrocholesterol reductase DKK3: Dickkopf-related protein 3 DPF2: Double PHD fingers 2 DRD4: Dopamine receptor D4 at 11p15.5 DSCAML1: encoding protein Down syndrome...
    28 KB (1,930 words) - 22:58, 28 March 2024
  • breaks into Hammond's home and steals multiple profiles of women with the DRD4 gene. When Hammond returns home, the intruder introduces himself as The Shrike...
    9 KB (1,266 words) - 03:52, 28 November 2023
  • Graham J. Thompson and colleagues identified the genes OXTR, CD38, COMT, DRD4, DRD5, IGF2, GABRB2 as candidates "affecting altruism". The geneticist Steve...
    20 KB (2,092 words) - 21:09, 19 July 2024
  • Thumbnail for Monoamine oxidase A
    (May 2002). "Family-based association study of 5-HTTLPR, TPH, MAO-A, and DRD4 polymorphisms in mood disorders". American Journal of Medical Genetics. 114...
    40 KB (4,635 words) - 19:38, 20 October 2024
  • Thumbnail for Rhodopsin-like receptors
    InterPro: IPR000929 D1 (DRD1, DADR) D2 (DRD2, D2DR) D3 (DRD3, D3DR) D4 (DRD4, D4DR) D5 (DRD5, DBDR) Trace amine receptor InterPro: IPR009132 TAAR1 (TAAR1...
    25 KB (2,172 words) - 01:01, 29 November 2023
  • Thumbnail for Impulsivity
    DAT1 polymorphisms have been shown to be linked to hyperactivity and ADHD. DRD4 is the dopamine D4 receptor gene and is associated with ADHD and novelty...
    143 KB (15,713 words) - 21:03, 3 September 2024
  • Thumbnail for Creativity and mental health
    also been linked to creativity. These include polymorphisms of the DRD2 and DRD4 genes, the 5HT2a gene, and the NRG1 gene. Several studies suggest a consistent...
    47 KB (5,495 words) - 07:14, 5 August 2024
  • Thumbnail for Apomorphine
    Ptácek R, Kuzelová H, Stefano GB (September 2011). "Dopamine D4 receptor gene DRD4 and its association with psychiatric disorders". Medical Science Monitor...
    55 KB (6,040 words) - 04:48, 15 September 2024
  • with dopaminergic pathways. Dopamine transporter DAT1 and dopamine receptor DRD4 are associated with novelty seeking.[citation needed] Parkinson's patients...
    16 KB (1,676 words) - 09:03, 25 May 2024