• Thumbnail for Deferasirox
    Deferasirox, sold under the brand name Exjade among others, is an oral iron chelator. Its main use is to reduce chronic iron overload in patients who...
    11 KB (783 words) - 05:56, 2 November 2024
  • reverse iron overload, using drugs such as deferoxamine, deferiprone, or deferasirox; medication with the antioxidant indicaxanthin to prevent the breakdown...
    44 KB (4,881 words) - 16:56, 27 October 2024
  • Thumbnail for Novartis
    methylphenidate (Ritalin; production ceased 2020), terbinafine (Lamisil), deferasirox (Exjade), and others. Novartis was formed in 1996 by the merger of Ciba-Geigy...
    151 KB (12,488 words) - 15:55, 30 November 2024
  • Thumbnail for Chelation therapy
    Chelation therapy Two molecules of deferasirox, an orally administered chelator, binding iron. Deferasirox is used in the treatment of transfusional iron...
    45 KB (4,444 words) - 14:25, 6 November 2024
  • Thumbnail for Beta thalassemia
    Popular chelators include deferoxamine and deferiprone. The oral chelator deferasirox was approved for use in 2005 in some countries. Bone marrow transplantation...
    57 KB (5,458 words) - 22:49, 19 September 2024
  • Complementary: Desmopressinα Heparin sodiumα Protamine sulfateα Warfarinα Deferasirox Complementary: Deferoxamineα Hydroxycarbamide (hydroxyurea)α Cryoprecipitate...
    67 KB (4,835 words) - 02:06, 4 December 2024
  • Thumbnail for Thalassemia
    is no evidence that deferasirox or deferiprone is superior, however, a long term comparison has not been performed. Deferasirox is not effective for...
    67 KB (7,028 words) - 21:43, 20 December 2024
  • Thumbnail for Congenital dyserythropoietic anemia
    they must undertake chelation therapy to survive; either deferoxamine, deferasirox, or deferiprone to eliminate the excess iron that accumulates. Removal...
    16 KB (1,303 words) - 21:28, 6 September 2024
  • Thumbnail for Ion-exchange resin
    method has only a limited efficacy, unlike small-molecular chelators (deferasirox, deferiprone, or deferoxamine), such an approach may have only minor...
    24 KB (3,017 words) - 02:10, 15 November 2024
  • Thumbnail for Myelodysplastic syndrome
    chelators are available in the US, deferoxamine for intravenous use and deferasirox for oral use. A third chelating agent is available, deferiprone, but...
    62 KB (6,504 words) - 05:26, 15 December 2024
  • Thumbnail for Iron overload
    thalassaemia (and, thus, who develop iron overload as a result) are deferasirox and deferiprone. A minimally invasive approach to hereditary hemochromatosis...
    46 KB (4,693 words) - 17:14, 29 October 2024
  • QV03AB96 Ropinirole V03AC01 Deferoxamine V03AC02 Deferiprone V03AC03 Deferasirox V03AE01 Polystyrene sulfonate V03AE02 Sevelamer V03AE03 Lanthanum carbonate...
    3 KB (373 words) - 00:33, 26 December 2023
  • Thumbnail for Hemosiderosis
    chelators. There are currently three licensed iron chelators, DFO, DFP and Deferasirox (DFX). The Guide for the Management of Transfusion Dependent Thalassaemia...
    12 KB (1,300 words) - 06:26, 24 November 2024
  • decoquinate (INN) dectaflur (INN) deditonium bromide (INN) Defencath deferasirox (USAN) deferiprone (INN) deferitrin (USAN) deferoxamine (INN) defibrotide...
    13 KB (574 words) - 05:26, 24 November 2024
  • Thumbnail for HFE H63D gene mutation
    Zusammenarbeit mit der Arzneimittelkommission der Deutschen Ärzteschaft: Deferasirox (Exjade)], Ausgabe 5-2008 (in German]p) Seideman et al. Preprint: Injury...
    24 KB (2,659 words) - 15:01, 26 October 2024
  • chelation therapy agent. Synthetic siderophores such as deferiprone and deferasirox have been developed, using the known structure of deferoxamine as a starting...
    15 KB (2,025 words) - 18:26, 12 July 2024
  • Thumbnail for Hereditary haemochromatosis
    administration of an iron chelator as Deferoxamine (or Desferrioxamine), Deferasirox and Deferiprone is useful. Deferoxamine is an iron-chelating compound...
    69 KB (7,315 words) - 08:22, 6 November 2024
  • Thumbnail for Transfusion-dependent anemia
    overload and common iron chelators used are deferoxamine, deferiprone and deferasirox. Due to the complications of transfusions dependency, it may be more...
    25 KB (2,854 words) - 16:14, 19 November 2024
  • quality-assured biosimilars. Alternatives are limited to the oral form of deferasirox. Polygeline, injectable solution, 3.5% is considered as equivalent. Alternatives...
    38 KB (2,574 words) - 02:05, 4 December 2024
  • Examples of chelators specifically for iron include deferoxamine and deferasirox. It is recommended that those with juvenile hemochromatosis refrain from...
    12 KB (1,259 words) - 07:38, 26 July 2023
  • delivering iron chelating agents such as deferoxamine, deferiprone or deferasirox. If iron overload has caused damage to end-organs, this is generally...
    7 KB (666 words) - 01:13, 25 February 2024
  • chelation, and folic acid. Iron chelation may be done with deferoxamine, deferasirox or deferiprone. Occasionally, a bone marrow transplant may be an option...
    20 KB (1,900 words) - 07:59, 26 October 2024