Deferasirox, sold under the brand name Exjade among others, is an oral iron chelator. Its main use is to reduce chronic iron overload in patients who...
11 KB (783 words) - 05:56, 2 November 2024
Management of thalassemia (section Deferasirox)
reverse iron overload, using drugs such as deferoxamine, deferiprone, or deferasirox; medication with the antioxidant indicaxanthin to prevent the breakdown...
44 KB (4,881 words) - 16:56, 27 October 2024
methylphenidate (Ritalin; production ceased 2020), terbinafine (Lamisil), deferasirox (Exjade), and others. Novartis was formed in 1996 by the merger of Ciba-Geigy...
151 KB (12,488 words) - 15:55, 30 November 2024
Chelation therapy Two molecules of deferasirox, an orally administered chelator, binding iron. Deferasirox is used in the treatment of transfusional iron...
45 KB (4,444 words) - 14:25, 6 November 2024
Popular chelators include deferoxamine and deferiprone. The oral chelator deferasirox was approved for use in 2005 in some countries. Bone marrow transplantation...
57 KB (5,458 words) - 22:49, 19 September 2024
Complementary: Desmopressinα Heparin sodiumα Protamine sulfateα Warfarinα Deferasirox Complementary: Deferoxamineα Hydroxycarbamide (hydroxyurea)α Cryoprecipitate...
67 KB (4,835 words) - 02:06, 4 December 2024
is no evidence that deferasirox or deferiprone is superior, however, a long term comparison has not been performed. Deferasirox is not effective for...
67 KB (7,028 words) - 21:43, 20 December 2024
they must undertake chelation therapy to survive; either deferoxamine, deferasirox, or deferiprone to eliminate the excess iron that accumulates. Removal...
16 KB (1,303 words) - 21:28, 6 September 2024
method has only a limited efficacy, unlike small-molecular chelators (deferasirox, deferiprone, or deferoxamine), such an approach may have only minor...
24 KB (3,017 words) - 02:10, 15 November 2024
chelators are available in the US, deferoxamine for intravenous use and deferasirox for oral use. A third chelating agent is available, deferiprone, but...
62 KB (6,504 words) - 05:26, 15 December 2024
thalassaemia (and, thus, who develop iron overload as a result) are deferasirox and deferiprone. A minimally invasive approach to hereditary hemochromatosis...
46 KB (4,693 words) - 17:14, 29 October 2024
QV03AB96 Ropinirole V03AC01 Deferoxamine V03AC02 Deferiprone V03AC03 Deferasirox V03AE01 Polystyrene sulfonate V03AE02 Sevelamer V03AE03 Lanthanum carbonate...
3 KB (373 words) - 00:33, 26 December 2023
chelators. There are currently three licensed iron chelators, DFO, DFP and Deferasirox (DFX). The Guide for the Management of Transfusion Dependent Thalassaemia...
12 KB (1,300 words) - 06:26, 24 November 2024
decoquinate (INN) dectaflur (INN) deditonium bromide (INN) Defencath deferasirox (USAN) deferiprone (INN) deferitrin (USAN) deferoxamine (INN) defibrotide...
13 KB (574 words) - 05:26, 24 November 2024
Zusammenarbeit mit der Arzneimittelkommission der Deutschen Ärzteschaft: Deferasirox (Exjade)], Ausgabe 5-2008 (in German]p) Seideman et al. Preprint: Injury...
24 KB (2,659 words) - 15:01, 26 October 2024
chelation therapy agent. Synthetic siderophores such as deferiprone and deferasirox have been developed, using the known structure of deferoxamine as a starting...
15 KB (2,025 words) - 18:26, 12 July 2024
administration of an iron chelator as Deferoxamine (or Desferrioxamine), Deferasirox and Deferiprone is useful. Deferoxamine is an iron-chelating compound...
69 KB (7,315 words) - 08:22, 6 November 2024
overload and common iron chelators used are deferoxamine, deferiprone and deferasirox. Due to the complications of transfusions dependency, it may be more...
25 KB (2,854 words) - 16:14, 19 November 2024
quality-assured biosimilars. Alternatives are limited to the oral form of deferasirox. Polygeline, injectable solution, 3.5% is considered as equivalent. Alternatives...
38 KB (2,574 words) - 02:05, 4 December 2024
Examples of chelators specifically for iron include deferoxamine and deferasirox. It is recommended that those with juvenile hemochromatosis refrain from...
12 KB (1,259 words) - 07:38, 26 July 2023
delivering iron chelating agents such as deferoxamine, deferiprone or deferasirox. If iron overload has caused damage to end-organs, this is generally...
7 KB (666 words) - 01:13, 25 February 2024
chelation, and folic acid. Iron chelation may be done with deferoxamine, deferasirox or deferiprone. Occasionally, a bone marrow transplant may be an option...
20 KB (1,900 words) - 07:59, 26 October 2024