Denosumab, sold under the brand names Prolia among others, is a human monoclonal antibody used for the treatment of osteoporosis, treatment-induced bone...
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imperfecta to reduce the risk of broken bones. Combined teriparatide and denosumab increased BMD more than either agent alone and more than has been reported...
27 KB (2,054 words) - 06:31, 7 July 2024
disparities exist. She has also appeared in commercials for Prolia, a brand of denosumab used in the treatment of osteoporosis. Danner was married to producer...
33 KB (1,657 words) - 19:58, 10 December 2024
medicamentosa. Denosumab inhibits osteoclast recycling, which results in the accumulation of pre-osteoclasts and osteomorphs. When denosumab therapy is discontinued...
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incident occurring in 2003. Osteonecrotic complications associated with denosumab, another antiresorptive drug from a different drug category, were soon...
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rhabdomyolysis, tumor lysis syndrome, and medications such as bisphosphonates or denosumab. Diagnosis should generally be confirmed by determining the corrected...
19 KB (1,867 words) - 20:33, 16 August 2024
tested in conjunction with calcium and vitamin D to encourage bone health. Denosumab, a monoclonal antibody treatment RANKl inhibitor that targets the osteocyte...
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60-90% of patients who were treated for hypercalcemia of malignancy. Denosumab is a bone anti-resorptive agent that can be used to treat hypercalcemia...
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it is no longer believed that they prevent progression of the disease. Denosumab has been found successful in reducing bone pain and decreasing tumor growth...
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relating to the US Food and Drug Administration (FDA)-approved Sandoz denosumab biosimilars. In November 2024, Sandoz inaugurated the new headquarters...
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metastases benefit from regular infusion of the bone-strengthening agents denosumab and the bisphosphonates; infusion every three months reduces the chance...
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and bone-targeting chemotherapeutic agents such as bisphosphonates and denosumab. Orthopedic interventions such as internal fixation or spinal decompression...
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baby's sex para-Dimethylaminobenzaldehyde, an organic chemical compound Denosumab, a drug for treating osteoporosis This disambiguation page lists articles...
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PMID 25729036. S2CID 43537545. Chiu YG, Ritchlin CT (January 2017). "Denosumab: targeting the RANKL pathway to treat rheumatoid arthritis". Expert Opinion...
152 KB (16,359 words) - 10:16, 17 December 2024
they shrink tumors. Other bone modifying agents like zoledronic acid and denosumab can reduce prostate cancer bone pain, even though they have little effect...
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adalimumab/Humira March 2024 denosumab-bbdz/Jubbonti denosumab/Prolia March 2024 denosumab-bbdz/Wyost denosumab/Xgeva March 2024 tocilizumab-aazg/Tyenne...
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PMID 24063695. S2CID 20163452. Gauthier K, Bai A, Perras C, et al. (2012). "Denosumab, Raloxifene, and Zoledronic Acid for the Treatment of Postmenopausal Osteoporosis:...
99 KB (9,725 words) - 06:42, 22 December 2024
Dulanermin Antibodies: Belimumab Brentuximab vedotin Conatumumab Dacetuzumab Denosumab Drozitumab Enavatuzumab Iratumumab Lexatumumab Lucatumumab Mapatumumab...
49 KB (6,227 words) - 14:52, 18 November 2024
osteoclast-like cells. More recently, humanized monoclonal antibodies such as Denosumab targeting the RANK ligand have been employed in treatment of GCTOB in...
14 KB (1,602 words) - 20:33, 21 December 2024
osteoporosis such as estrogen replacement therapy, bisphosphonates or denosumab and for treatment hypercalciuria to reduce the risk for kidney stones...
22 KB (2,314 words) - 22:30, 13 August 2024
one year, and the benefit was maintained after a second year of taking denosumab. In the other, one year of romosozumab followed by one year of alendronate...
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avenue of development for strategies targeting NF-κB inhibition. The drug denosumab acts to raise bone mineral density and reduce fracture rates in many patient...
89 KB (9,787 words) - 19:09, 28 November 2024
(esomeprazole) (only in Japan; marketed by AstraZeneca elsewhere) Pralia (denosumab) (only available in Japan; also sold there as Ranmark) Tarlige (mirogabalin)...
29 KB (2,365 words) - 00:42, 19 December 2024
Optimal treatment for this condition is unclear. Bisphosphonates and denosumab may be of use for the bone lesions. Cyclosporine A may be of use for treating...
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C; Cunningham, J; Ahuja, T; Richter, T; Kovacs, C (February 2012). "Denosumab, Raloxifene, and Zoledronic Acid for the Treatment of Postmenopausal Osteoporosis:...
30 KB (3,437 words) - 08:59, 3 December 2024
breast cancer, it increases the risk of blood clots and strokes. While denosumab is effective at preventing fractures in women, there is not clear evidence...
139 KB (15,817 words) - 23:38, 9 December 2024
in 2023. Products under development include biosimilars of omalizumab, denosumab, golimumab, aflibercept, vedolizumab, and pembrolizumab. In November 2022...
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(FDA approved 2008) Otezla (apremilast) Parsabiv (etelcalcetide) Prolia (denosumab) for postmenopausal osteoporosis Repatha (evolocumab) Riabni (rituximab-arrx)...
99 KB (8,021 words) - 16:43, 20 December 2024
Pharmaceutical, Hetero Drugs, Roche Influenza Oct-1999 Mon-20XX 91 Xgeva Denosumab 197,711 3.24% Amgen Osteoporosis Nov-2010 Mon-20XX 92 Evista Raloxifene...
29 KB (281 words) - 06:29, 12 August 2024