• Thumbnail for Denosumab
    Denosumab, sold under the brand names Prolia among others, is a human monoclonal antibody used for the treatment of osteoporosis, treatment-induced bone...
    32 KB (2,850 words) - 05:10, 17 December 2024
  • Thumbnail for RANKL
    RANKL (section Denosumab)
    some were given either 120 mg of denosumab or 4 mg of zoledronic acid. Patients who were given 120 mg of denosumab (in comparison to those who were given...
    28 KB (3,305 words) - 13:29, 8 November 2024
  • Thumbnail for Teriparatide
    imperfecta to reduce the risk of broken bones. Combined teriparatide and denosumab increased BMD more than either agent alone and more than has been reported...
    27 KB (2,054 words) - 06:31, 7 July 2024
  • Thumbnail for Blythe Danner
    disparities exist. She has also appeared in commercials for Prolia, a brand of denosumab used in the treatment of osteoporosis. Danner was married to producer...
    33 KB (1,657 words) - 19:58, 10 December 2024
  • medicamentosa. Denosumab inhibits osteoclast recycling, which results in the accumulation of pre-osteoclasts and osteomorphs. When denosumab therapy is discontinued...
    12 KB (1,355 words) - 06:02, 11 November 2024
  • Thumbnail for Medication-related osteonecrosis of the jaw
    incident occurring in 2003. Osteonecrotic complications associated with denosumab, another antiresorptive drug from a different drug category, were soon...
    46 KB (4,835 words) - 18:24, 9 December 2023
  • Thumbnail for Hypocalcemia
    rhabdomyolysis, tumor lysis syndrome, and medications such as bisphosphonates or denosumab. Diagnosis should generally be confirmed by determining the corrected...
    19 KB (1,867 words) - 20:33, 16 August 2024
  • Thumbnail for Osteolytic lesion
    tested in conjunction with calcium and vitamin D to encourage bone health. Denosumab, a monoclonal antibody treatment RANKl inhibitor that targets the osteocyte...
    6 KB (673 words) - 17:26, 24 September 2024
  • 60-90% of patients who were treated for hypercalcemia of malignancy. Denosumab is a bone anti-resorptive agent that can be used to treat hypercalcemia...
    34 KB (3,298 words) - 14:09, 15 November 2024
  • Thumbnail for McCune–Albright syndrome
    it is no longer believed that they prevent progression of the disease. Denosumab has been found successful in reducing bone pain and decreasing tumor growth...
    22 KB (2,346 words) - 19:54, 23 August 2024
  • relating to the US Food and Drug Administration (FDA)-approved Sandoz denosumab biosimilars. In November 2024, Sandoz inaugurated the new headquarters...
    36 KB (2,804 words) - 02:21, 10 December 2024
  • Thumbnail for Breast cancer
    metastases benefit from regular infusion of the bone-strengthening agents denosumab and the bisphosphonates; infusion every three months reduces the chance...
    140 KB (15,850 words) - 19:18, 21 December 2024
  • Thumbnail for Bone metastasis
    and bone-targeting chemotherapeutic agents such as bisphosphonates and denosumab. Orthopedic interventions such as internal fixation or spinal decompression...
    26 KB (2,714 words) - 06:49, 16 September 2024
  • baby's sex para-Dimethylaminobenzaldehyde, an organic chemical compound Denosumab, a drug for treating osteoporosis This disambiguation page lists articles...
    322 bytes (70 words) - 21:26, 7 May 2018
  • Thumbnail for Rheumatoid arthritis
    PMID 25729036. S2CID 43537545. Chiu YG, Ritchlin CT (January 2017). "Denosumab: targeting the RANKL pathway to treat rheumatoid arthritis". Expert Opinion...
    152 KB (16,359 words) - 10:16, 17 December 2024
  • Thumbnail for Prostate cancer
    they shrink tumors. Other bone modifying agents like zoledronic acid and denosumab can reduce prostate cancer bone pain, even though they have little effect...
    77 KB (8,906 words) - 21:26, 12 December 2024
  • adalimumab/Humira March 2024 denosumab-bbdz/Jubbonti denosumab/Prolia March 2024 denosumab-bbdz/Wyost denosumab/Xgeva March 2024 tocilizumab-aazg/Tyenne...
    97 KB (6,513 words) - 22:57, 3 December 2024
  • Thumbnail for Merck & Co.
    PMID 24063695. S2CID 20163452. Gauthier K, Bai A, Perras C, et al. (2012). "Denosumab, Raloxifene, and Zoledronic Acid for the Treatment of Postmenopausal Osteoporosis:...
    99 KB (9,725 words) - 06:42, 22 December 2024
  • Thumbnail for Tumor necrosis factor
    Dulanermin Antibodies: Belimumab Brentuximab vedotin Conatumumab Dacetuzumab Denosumab Drozitumab Enavatuzumab Iratumumab Lexatumumab Lucatumumab Mapatumumab...
    49 KB (6,227 words) - 14:52, 18 November 2024
  • Thumbnail for Giant-cell tumor of bone
    osteoclast-like cells. More recently, humanized monoclonal antibodies such as Denosumab targeting the RANK ligand have been employed in treatment of GCTOB in...
    14 KB (1,602 words) - 20:33, 21 December 2024
  • Thumbnail for Primary hyperparathyroidism
    osteoporosis such as estrogen replacement therapy, bisphosphonates or denosumab and for treatment hypercalciuria to reduce the risk for kidney stones...
    22 KB (2,314 words) - 22:30, 13 August 2024
  • one year, and the benefit was maintained after a second year of taking denosumab. In the other, one year of romosozumab followed by one year of alendronate...
    12 KB (892 words) - 01:49, 7 December 2024
  • Thumbnail for NF-κB
    avenue of development for strategies targeting NF-κB inhibition. The drug denosumab acts to raise bone mineral density and reduce fracture rates in many patient...
    89 KB (9,787 words) - 19:09, 28 November 2024
  • Thumbnail for Daiichi Sankyo
    (esomeprazole) (only in Japan; marketed by AstraZeneca elsewhere) Pralia (denosumab) (only available in Japan; also sold there as Ranmark) Tarlige (mirogabalin)...
    29 KB (2,365 words) - 00:42, 19 December 2024
  • Thumbnail for Multicentric carpotarsal osteolysis syndrome
    Optimal treatment for this condition is unclear. Bisphosphonates and denosumab may be of use for the bone lesions. Cyclosporine A may be of use for treating...
    5 KB (518 words) - 20:18, 17 May 2023
  • Thumbnail for Bisphosphonate
    C; Cunningham, J; Ahuja, T; Richter, T; Kovacs, C (February 2012). "Denosumab, Raloxifene, and Zoledronic Acid for the Treatment of Postmenopausal Osteoporosis:...
    30 KB (3,437 words) - 08:59, 3 December 2024
  • Thumbnail for Osteoporosis
    breast cancer, it increases the risk of blood clots and strokes. While denosumab is effective at preventing fractures in women, there is not clear evidence...
    139 KB (15,817 words) - 23:38, 9 December 2024
  • in 2023. Products under development include biosimilars of omalizumab, denosumab, golimumab, aflibercept, vedolizumab, and pembrolizumab. In November 2022...
    11 KB (914 words) - 20:13, 22 June 2024
  • Thumbnail for Amgen
    (FDA approved 2008) Otezla (apremilast) Parsabiv (etelcalcetide) Prolia (denosumab) for postmenopausal osteoporosis Repatha (evolocumab) Riabni (rituximab-arrx)...
    99 KB (8,021 words) - 16:43, 20 December 2024
  • Pharmaceutical, Hetero Drugs, Roche Influenza Oct-1999 Mon-20XX 91 Xgeva Denosumab 197,711 3.24% Amgen Osteoporosis Nov-2010 Mon-20XX 92 Evista Raloxifene...
    29 KB (281 words) - 06:29, 12 August 2024