A deoxyadenosyl radical is a free radical that is structurally related to adenosine by removal of a 5′-hydroxy group from adenosine. This radical occurs...

interconversion using three cofactors and a 5'-deoxyadenosyl radical formed in a S-Adenosyl methionine (SAM) activated radical reaction pathway.[1] Shown on the right...

(SAM) to generate a radical, usually a 5′-deoxyadenosyl radical (5'-dAdo), as a critical intermediate. These enzymes utilize this radical intermediate to...

a cofactor in radical-mediated 1,2-carbon skeleton rearrangements. These processes require the formation of the deoxyadenosyl radical through homolytic...

radicals highly chemically reactive. Many radicals spontaneously dimerize. Most organic radicals have short lifetimes. A notable example of a radical...

5'-deoxyadenosyl radical by homolytic cleavage of the C-Co bond in adenosylcobalamin. In addition, Class III RNRs contain a stable glycyl radical. Humans...

above 200°C. Adenosylcobalamin is the cofactor which creates the deoxyadenosyl radical by homolytic cleavage of a cobalt-carbon bond in reactions catalysed...

ligand 5’-deoxy-5’-adenosine reversibly dissociated to give the deoxyadenosyl radical. The α-axial ligand 5,6-dimethylbenzimidazole (DMB) is involved...

chemistry of vitamin B12, allowing it to serve as a donor of deoxyadenosyl radical (radical alkyl source) and as a methyl cation equivalent (electrophilic...

generating a 5’-deoxyadenosyl radical (5’-dA). This carbon radical abstracts a hydrogen from dethiobiotin, forming a dethiobiotinyl C9 carbon radical, which is...

the 5' CH 2- of 5'-deoxyadenosyl and the cobalt, which is in its 3+ oxidation state (III), which produces a 5'-deoxyadenosyl radical and cobalamin in the...

enzyme is to generate a 5′-deoxyadenosyl radical by homolytic cleavage of the cobalt-carbon bond of the cofactor. This radical abstracts a hydrogen atom...

which cleaves a part of the structure and forms a 5'-deoxyadenosyl radical. This 5'-deoxyadenosyl radical will then remove a hydrogen atom from the substrate...

radical (G*) via a 5'-deoxyadenosyl radical (via a radical SAM). For more information about radical SAM activation and radical SAM enzymes, see the discussion...

adenosylcobalamin to form cob(II)alamin and the 5'-deoxyadenosyl radical, and thus act as radical generators. In both types of enzymes the B12-binding...

to the 5'-deoxyadenosyl radical through interactions with the enzyme's iron-sulfur cluster. 3. A radical forms along with 5'-deoxyadenosyl, which remains...

4Fe-4S cluster. The condensation reaction is initiated by the 5'-deoxyadenosyl radical. The complex was formerly named as a single entity under EC 2.5...

stabilizing the radical intermediate by captodative stabilization and spin delocalization. Catalysis begins with a 5'-deoxyadenosyl radical (Ado-CH2•), and...

SAM reductively to produce radicals: 5′-deoxyadenosyl 5′-radical, methyl radical, and others. These enzymes are called radical SAMs. They all feature iron-sulfur...

is used by this enzyme to produce 5'-deoxyadenosyl 5'-radical (5'-dA). Lipoyl synthase itself uses this radical to abstract hydrogens from the 6th and...

otherwise known as radical SAM enzymes, are metalloproteins that cleave S-adenosyl-L-methionine into L-methionine and a 5'-deoxyadenosyl 5'-radical (5'-dA). 5'-dA...