Deoxyuridine monophosphate (dUMP), also known as deoxyuridylic acid or deoxyuridylate in its conjugate acid and conjugate base forms, respectively, is...
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Deoxyadenosine monophosphate Deoxyuridine monophosphate Deoxycytidine monophosphate Deoxyguanosine monophosphate Boron monophosphate Aluminium monophosphate Scandium...
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is thymidylate synthase, which creates thymidine monophosphate (TMP) from deoxyuridine monophosphate (dUMP). By additional phosphorylation reactions,...
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an enzyme that catalyzes the conversion of deoxyuridine monophosphate (dUMP) to deoxythymidine monophosphate (dTMP). Thymidine is one of the nucleotides...
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Edward Island Ammunition dump, military stores of ammunition Deoxyuridine monophosphate, or dUMP Margaret Mitchell House and Museum, where Margaret Mitchell...
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the methylation of C5 of deoxyuridine monophosphate (dUMP) thereby inhibiting the synthesis of deoxythymidine monophosphate (dTMP). The downstream effect...
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replication. Thymidylate synthase methylates deoxyuridine monophosphate (dUMP) to form thymidine monophosphate (dTMP). Administration of 5-FU causes a scarcity...
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DCMP deaminase (redirect from Deoxycytidine monophosphate deaminase)
deoxycytidylic acid to deoxyuridylic acid. Deoxycytidine monophosphate Deoxyuridine monophosphate Scarano E (March 1960). "The enzymatic deamination of 6-aminopyrimidine...
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(vitamin B9); DMG: dimethylglycine; dTMP: thymidine monophosphate; dUMP: deoxyuridine monophosphate; FAD+ flavine adenine dicucleotide; FTHF: 10-formyltetrahydrofolate;...
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synthase, for methylation of 2-deoxy-uridine-5-monophosphate (dUMP) to 2-deoxy-thymidine-5-monophosphate (dTMP). The coenzyme is necessary for the biosynthesis...
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(vitamin B9); DMG: dimethylglycine; dTMP: thymidine monophosphate; dUMP: deoxyuridine monophosphate; FAD+ flavine adenine dicucleotide; FTHF: 10-formyltetrahydrofolate;...
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(vitamin B9); DMG: dimethylglycine; dTMP: thymidine monophosphate; dUMP: deoxyuridine monophosphate; FAD+ flavine adenine dicucleotide; FTHF: 10-formyltetrahydrofolate;...
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Specific examples include methylene diurea and ethylene diurea. dUMP Deoxyuridine monophosphate, an intermediate in nucleotide metabolism Earthcide, or Fartox...
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Floxuridine (redirect from 5-fluoro-2'-deoxyuridine)
preformed uracil in RNA synthesis. As well, the monophosphate of floxuridine, 5-fluoro-2'-deoxyuridine-5'-phosphate (FUDR-MP) inhibits the enzyme thymidylate...
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retrovirus). Thymidine monophosphate is also produced by the cell in a different reaction by methylation of deoxyuridine monophosphate, a product of other...
103 KB (11,263 words) - 15:52, 2 November 2024
TS to bromovinyldeoxyuridine monophosphate (BVdUMP) which competes with the natural substrate, deoxyuridine monophosphate, for binding to TS. Unlike TS...
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deficiency in folate leads to increased ratio of deoxyuridine monophosphates (dUMP)/deoxythymidine monophosphates (dTMP) and uracil misincorporation into DNA...
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to allow the proper glycolysis of galactose. Deoxyuridine monophosphate Pseudouridine Uridine monophosphate International Union of Pure and Applied Chemistry...
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to uridine and deoxyuridine, respectively. Alternatively, uridine–cytidine kinase can phosphorylate them into cytidine monophosphate (CMP) or deoxycytidine...
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Inhibition of TS depletes the cell of dTTP and causes accumulation of deoxyuridine monophosphate (dUMP), which increases the likelihood that uracil gets misincorporated...
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Fluorodeoxyuridylate (redirect from 5-Fluorodeoxyuridine monophosphate)
known as FdUMP, 5-fluoro-2'-deoxyuridylate, and 5-fluoro-2'-deoxyuridine 5'-monophosphate, is a molecule formed in vivo from 5-fluorouracil and 5-fluorodeoxyuridine...
11 KB (1,304 words) - 20:08, 18 October 2024
dihydrofolate, FdUMP = fluorodeoxyuridine-5′-monophosphate, dUMP = deoxyuridine monophosphate, dTMP = deoxythymidine monophosphate. From Nonaka et al., 2019....
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Shown is a PyMol image of the ribonuclease 4 dimer, blue, with deoxyuridine monophosphate, white, in the active site. PDB: 2RNF...
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synthetase. Thymidine synthesis first requires reduction of the uridine to deoxyuridine (see next section), before the base can be methylated to produce thymidine...
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as disseminated shingles). The original compounds used were 5-iodo-2'-deoxyuridine, AKA idoxuridine, IUdR, or(IDU) and 1-β-D-arabinofuranosylcytosine or...
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two or three phosphoric acid groups, creating dTMP (deoxythymidine monophosphate), dTDP, or dTTP (for the di- and tri- phosphates, respectively). It...
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phosphorylation of thymidine as described above or by methylation of deoxyuridine monophosphate, a product of other metabolic pathways unrelated to thymidine...
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whereby nucleotidases break down nucleotides (such as the thymidine monophosphate) into nucleosides (such as thymidine) and phosphate. The nucleosides...
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form at least two active products; 5-fluourouridine monophosphate (FUMP) and 5-fluoro-2'-deoxyuridine 5'-phosphate (fdUMP). FUMP becomes incorporated into...
155 KB (17,526 words) - 23:36, 26 October 2024
biosynthesis of dTMP (2′-deoxythymidine-5′-phosphate) from dUMP (2′-deoxyuridine-5′-phosphate). The conversion is catalyzed by thymidylate synthase. Methyl-THF...
106 KB (11,313 words) - 04:52, 19 November 2024