• Thumbnail for Deoxyuridine monophosphate
    Deoxyuridine monophosphate (dUMP), also known as deoxyuridylic acid or deoxyuridylate in its conjugate acid and conjugate base forms, respectively, is...
    4 KB (259 words) - 13:43, 25 April 2024
  • Deoxyadenosine monophosphate Deoxyuridine monophosphate Deoxycytidine monophosphate Deoxyguanosine monophosphate Boron monophosphate Aluminium monophosphate Scandium...
    1 KB (127 words) - 16:44, 19 January 2024
  • Thumbnail for HAT medium
    is thymidylate synthase, which creates thymidine monophosphate (TMP) from deoxyuridine monophosphate (dUMP). By additional phosphorylation reactions,...
    5 KB (638 words) - 02:17, 12 May 2024
  • Thumbnail for Thymidylate synthase
    an enzyme that catalyzes the conversion of deoxyuridine monophosphate (dUMP) to deoxythymidine monophosphate (dTMP). Thymidine is one of the nucleotides...
    16 KB (1,902 words) - 00:29, 10 March 2024
  • Edward Island Ammunition dump, military stores of ammunition Deoxyuridine monophosphate, or dUMP Margaret Mitchell House and Museum, where Margaret Mitchell...
    2 KB (335 words) - 14:56, 30 August 2024
  • the methylation of C5 of deoxyuridine monophosphate (dUMP) thereby inhibiting the synthesis of deoxythymidine monophosphate (dTMP). The downstream effect...
    4 KB (380 words) - 10:51, 22 April 2024
  • replication. Thymidylate synthase methylates deoxyuridine monophosphate (dUMP) to form thymidine monophosphate (dTMP). Administration of 5-FU causes a scarcity...
    31 KB (2,796 words) - 07:50, 10 August 2024
  • Thumbnail for DCMP deaminase
    deoxycytidylic acid to deoxyuridylic acid. Deoxycytidine monophosphate Deoxyuridine monophosphate Scarano E (March 1960). "The enzymatic deamination of 6-aminopyrimidine...
    2 KB (186 words) - 03:34, 28 October 2022
  • Thumbnail for Levomefolic acid
    (vitamin B9); DMG: dimethylglycine; dTMP: thymidine monophosphate; dUMP: deoxyuridine monophosphate; FAD+ flavine adenine dicucleotide; FTHF: 10-formyltetrahydrofolate;...
    15 KB (1,173 words) - 11:42, 25 June 2024
  • Thumbnail for 5,10-Methylenetetrahydrofolate
    synthase, for methylation of 2-deoxy-uridine-5-monophosphate (dUMP) to 2-deoxy-thymidine-5-monophosphate (dTMP). The coenzyme is necessary for the biosynthesis...
    6 KB (324 words) - 18:37, 28 April 2023
  • Thumbnail for Homocysteine
    (vitamin B9); DMG: dimethylglycine; dTMP: thymidine monophosphate; dUMP: deoxyuridine monophosphate; FAD+ flavine adenine dicucleotide; FTHF: 10-formyltetrahydrofolate;...
    25 KB (2,076 words) - 02:02, 19 November 2024
  • Thumbnail for Methylenetetrahydrofolate reductase
    (vitamin B9); DMG: dimethylglycine; dTMP: thymidine monophosphate; dUMP: deoxyuridine monophosphate; FAD+ flavine adenine dicucleotide; FTHF: 10-formyltetrahydrofolate;...
    34 KB (3,737 words) - 07:12, 15 April 2024
  • Specific examples include methylene diurea and ethylene diurea. dUMP Deoxyuridine monophosphate, an intermediate in nucleotide metabolism Earthcide, or Fartox...
    44 KB (1,916 words) - 01:53, 24 November 2024
  • Thumbnail for Floxuridine
    preformed uracil in RNA synthesis. As well, the monophosphate of floxuridine, 5-fluoro-2'-deoxyuridine-5'-phosphate (FUDR-MP) inhibits the enzyme thymidylate...
    12 KB (1,274 words) - 06:04, 4 January 2024
  • Thumbnail for Thymidine kinase
    retrovirus). Thymidine monophosphate is also produced by the cell in a different reaction by methylation of deoxyuridine monophosphate, a product of other...
    103 KB (11,263 words) - 15:52, 2 November 2024
  • Thumbnail for Thymectacin
    TS to bromovinyldeoxyuridine monophosphate (BVdUMP) which competes with the natural substrate, deoxyuridine monophosphate, for binding to TS. Unlike TS...
    3 KB (153 words) - 14:07, 12 August 2023
  • Thumbnail for Uracil
    deficiency in folate leads to increased ratio of deoxyuridine monophosphates (dUMP)/deoxythymidine monophosphates (dTMP) and uracil misincorporation into DNA...
    29 KB (2,943 words) - 16:12, 20 November 2024
  • Thumbnail for Uridine
    to allow the proper glycolysis of galactose. Deoxyuridine monophosphate Pseudouridine Uridine monophosphate International Union of Pure and Applied Chemistry...
    12 KB (1,228 words) - 08:03, 7 January 2024
  • to uridine and deoxyuridine, respectively. Alternatively, uridine–cytidine kinase can phosphorylate them into cytidine monophosphate (CMP) or deoxycytidine...
    7 KB (736 words) - 10:22, 12 August 2024
  • Thumbnail for Trifluridine/tipiracil
    Inhibition of TS depletes the cell of dTTP and causes accumulation of deoxyuridine monophosphate (dUMP), which increases the likelihood that uracil gets misincorporated...
    12 KB (1,098 words) - 03:49, 14 August 2024
  • Thumbnail for Fluorodeoxyuridylate
    known as FdUMP, 5-fluoro-2'-deoxyuridylate, and  5-fluoro-2'-deoxyuridine 5'-monophosphate, is a molecule formed in vivo from 5-fluorouracil and 5-fluorodeoxyuridine...
    11 KB (1,304 words) - 20:08, 18 October 2024
  • Thumbnail for Serine hydroxymethyltransferase
    dihydrofolate, FdUMP = fluorodeoxyuridine-5′-monophosphate, dUMP = deoxyuridine monophosphate, dTMP = deoxythymidine monophosphate. From Nonaka et al., 2019....
    23 KB (2,378 words) - 10:15, 25 March 2024
  • Thumbnail for Ribonuclease 4
    Shown is a PyMol image of the ribonuclease 4 dimer, blue, with deoxyuridine monophosphate, white, in the active site. PDB: 2RNF...
    8 KB (929 words) - 19:10, 24 July 2024
  • Thumbnail for Nucleic acid metabolism
    synthetase. Thymidine synthesis first requires reduction of the uridine to deoxyuridine (see next section), before the base can be methylated to produce thymidine...
    13 KB (1,457 words) - 22:06, 24 December 2023
  • Thumbnail for Herpes
    as disseminated shingles). The original compounds used were 5-iodo-2'-deoxyuridine, AKA idoxuridine, IUdR, or(IDU) and 1-β-D-arabinofuranosylcytosine or...
    81 KB (8,822 words) - 08:17, 2 November 2024
  • Thumbnail for Thymidine
    two or three phosphoric acid groups, creating dTMP (deoxythymidine monophosphate), dTDP, or dTTP (for the di- and tri- phosphates, respectively). It...
    8 KB (778 words) - 04:55, 8 November 2024
  • phosphorylation of thymidine as described above or by methylation of deoxyuridine monophosphate, a product of other metabolic pathways unrelated to thymidine...
    83 KB (9,990 words) - 04:54, 15 July 2024
  • Thumbnail for Nucleoside
    whereby nucleotidases break down nucleotides (such as the thymidine monophosphate) into nucleosides (such as thymidine) and phosphate. The nucleosides...
    10 KB (813 words) - 19:42, 12 August 2024
  • Thumbnail for Chemotherapy
    form at least two active products; 5-fluourouridine monophosphate (FUMP) and 5-fluoro-2'-deoxyuridine 5'-phosphate (fdUMP). FUMP becomes incorporated into...
    155 KB (17,526 words) - 23:36, 26 October 2024
  • Thumbnail for Folate
    biosynthesis of dTMP (2′-deoxythymidine-5′-phosphate) from dUMP (2′-deoxyuridine-5′-phosphate). The conversion is catalyzed by thymidylate synthase. Methyl-THF...
    106 KB (11,313 words) - 04:52, 19 November 2024