• Thumbnail for Diacylglycerol O-acyltransferase 2
    Diacylglycerol O-acyltransferase 2 (DGAT2) is a protein that in humans is encoded by the DGAT2 gene. This gene encodes one of two enzymes which catalyzes...
    5 KB (629 words) - 01:46, 11 December 2023
  • In enzymology, a diacylglycerol-sterol O-acyltransferase (EC 2.3.1.73) is an enzyme that catalyzes the chemical reaction 1,2-diacyl-sn-glycerol + sterol...
    2 KB (221 words) - 21:41, 21 June 2024
  • Diglyceride acyltransferase (or O-acyltransferase), DGAT, catalyzes the formation of triglycerides (triacylglycerols) from diacylglycerol and acyl-CoA...
    7 KB (705 words) - 17:51, 6 May 2024
  • phospholipid:diacylglycerol acyltransferase (EC 2.3.1.158) is an enzyme that catalyzes the chemical reaction phospholipid + 1,2-diacylglycerol ⇌ {\displaystyle...
    2 KB (172 words) - 15:25, 26 August 2023
  • In enzymology, a 2-acylglycerol O-acyltransferase (EC 2.3.1.22) is an enzyme that catalyzes the chemical reaction acyl-CoA + 2-acylglycerol ⇌ {\displaystyle...
    2 KB (143 words) - 12:25, 26 August 2023
  • In enzymology, a triacylglycerol---sterol O-acyltransferase (EC 2.3.1.77) is an enzyme that catalyzes the chemical reaction triacylglycerol + a 3beta-hydroxysterol...
    2 KB (127 words) - 16:05, 26 August 2023
  • Thumbnail for Diglyceride
    Diglyceride (redirect from Diacylglycerol)
    addition of a third fatty acid to the diacylglycerol under the catalysis of diglyceride acyltransferase. Since diacylglycerol is synthesized via phosphatidic...
    9 KB (925 words) - 10:07, 15 October 2023
  • In enzymology, a long-chain-alcohol O-fatty-acyltransferase (EC 2.3.1.75) is an enzyme that catalyzes the chemical reaction acyl-CoA + a long-chain alcohol...
    14 KB (1,815 words) - 20:36, 3 December 2023
  • Thumbnail for DGAT1
    Diacylglycerol O-acyltransferase 1 is an enzyme that in humans is encoded by the DGAT1 gene. This gene encodes a multipass transmembrane protein that functions...
    4 KB (514 words) - 19:39, 6 May 2024
  • Thumbnail for Lecithin–cholesterol acyltransferase
    Lecithin–cholesterol acyltransferase (LCAT, also called phosphatidylcholine–sterol O-acyltransferase) is an enzyme, in many animals including humans,...
    9 KB (1,142 words) - 13:01, 1 March 2023
  • Thumbnail for MBOAT5
    Lysophospholipid acyltransferase 5 is an enzyme that in humans is encoded by the LPCAT3 gene. It is homologous to other membrane-bound O-acyltransferases. Based...
    7 KB (772 words) - 20:08, 22 February 2024
  • Thumbnail for Ervogastat
    Ervogastat is an experimental small-molecule drug and selective diacylglycerol O-acyltransferase 2 inhibitor developed by Pfizer for non-alcoholic steatohepatitis...
    4 KB (172 words) - 21:25, 24 November 2023
  • Thumbnail for MOGAT2
    2-Acylglycerol O-acyltransferase 2 also known as acyl-CoA:monoacylglycerol acyltransferase 2 (MGAT2) or Diacylglycerol O-acyltransferase candidate 5 (DC5)...
    4 KB (572 words) - 18:15, 5 April 2024
  • regularly produces oils). Expression of Umbelopsis ramanniana diacylglycerol O-acyltransferase 2A in seed increases oil in soybean without reduction of other...
    11 KB (1,626 words) - 08:54, 18 May 2024
  • Thumbnail for MOGAT3
    Monoacylglycerol O-acyltransferase 3 is a protein that in humans is encoded by the MOGAT3 gene. Acyl-CoA:monoacylglycerol acyltransferase (MOGAT; EC 2.3...
    1 KB (188 words) - 23:53, 3 March 2023
  • the hydrolysis of the P-O bond of phosphatidylcholine (PC) to produce PA and choline. By the phosphorylation of diacylglycerol (DAG) by DAG kinase (DAGK)...
    25 KB (3,086 words) - 00:31, 3 December 2023
  • Thumbnail for Niacin
    its production. Niacin also directly inhibits the action of diacylglycerol O-acyltransferase 2 (DGAT2) a key enzyme for triglyceride synthesis. The mechanism...
    92 KB (8,789 words) - 16:52, 1 July 2024
  • EC 2.3.1.20: diacylglycerol O-acyltransferase EC 2.3.1.21: carnitine O-palmitoyltransferase EC 2.3.1.22: 2-acylglycerol O-acyltransferase EC 2.3.1.23:...
    215 KB (21,664 words) - 23:41, 8 May 2024
  • Thumbnail for Chromosome 11
    inducible 1 homolog 1 (S. cerevisiae) DGAT2 encoding protein Diacylglycerol O-acyltransferase 2 DHCR7: 7-dehydrocholesterol reductase DKK3: Dickkopf-related...
    28 KB (1,930 words) - 22:58, 28 March 2024
  • two products were CoA and CDP-diacylglycerol. Such enzyme were describes as transferases, specifically acyltransferases transferring groups other than...
    3 KB (236 words) - 18:50, 26 August 2023
  • Thumbnail for Lysocardiolipin acyltransferase 1
    Lysocardiolipin acyltransferase 1 is a protein that in humans is encoded by the LCLAT1 gene. GRCh38: Ensembl release 89: ENSG00000172954 – Ensembl, May...
    839 bytes (115 words) - 01:49, 11 December 2023
  • Thumbnail for GPAT4
    Glycerol-3-phosphate acyltransferase 4 is a glycerol-3-phosphate acyltransferase that in humans is encoded by the GPAT4 gene. GPAT4 is involved in the...
    3 KB (432 words) - 01:47, 11 December 2023
  • Thumbnail for Phosphatidylinositol
    forms the second messengers, inositol (1,4,5) triphosphate (IP3) and diacylglycerol (DG). DG is then phosphyrylated to phosphatidic acid (PA) by DG kinase...
    20 KB (2,015 words) - 11:15, 18 July 2024
  • Thumbnail for AGPAT3
    gene is an acyltransferase (specifically, 1-acylglycerol-3-phosphate O-acyltransferase) that converts lysophosphatidic acid (1-acyl-sn-glycerol 3-phosphate)...
    4 KB (509 words) - 20:29, 5 June 2024
  • Thumbnail for 1-Lysophosphatidylcholine
    triacylglycerol synthesis can be catalyzed by phospholipid:diacylglycerol acyltransferase (PDAT). Thus, diacylglycerol is the acceptor of a fatty acid coming from phosphatidylcholine...
    25 KB (2,167 words) - 15:26, 3 February 2024
  • Thumbnail for SOAT2
    Sterol O-acyltransferase 2, also known as SOAT2, is an enzyme that in humans is encoded by the SOAT2 gene. This gene is a member of a small family of...
    8 KB (972 words) - 18:17, 11 November 2023
  • Thumbnail for Acyl-CoA
    can mediate lipotoxicity in non-adipose tissues. Acyl-CoA: diacylglycerol acyltransferase (DGAT) plays an important role in energy metabolism on account...
    11 KB (1,195 words) - 19:28, 5 June 2024
  • Thumbnail for SOAT1
    Sterol O-acyltransferase (acyl-Coenzyme A: cholesterol acyltransferase) 1, also known as SOAT1, is an enzyme that in humans is encoded by the SOAT1 gene...
    11 KB (1,414 words) - 06:12, 10 March 2024
  • investigated. Its biosynthesis is catalyzed by the wax ester/acyl-CoA:diacylglycerol acyltransferase enzymes, which is associated with the atf genes, A study investigating...
    8 KB (1,051 words) - 16:29, 13 March 2024
  • Thumbnail for Glycerophospholipid
    PMID 24462586. Yong-Mei Zhang and Charles O. Rock (2008). "Thematic Review Series: Glycerolipids. Acyltransferases in bacterial glycerophospholipid synthesis"...
    18 KB (2,269 words) - 01:56, 30 June 2024