Dihexa (developmental code PNB-0408; also known as N-hexanoic-Tyr-Ile-(6) aminohexanoic amide) is an oligopeptide drug derived from angiotensin IV that...
7 KB (492 words) - 08:38, 3 October 2024
and Parkinson's disease. It is a pro-drug of the active metabolite dihexa. Dihexa in turn binds to the hepatocyte growth factor (HGF) and potentiates...
3 KB (102 words) - 12:44, 8 October 2024
HGF (c-Met) Agonists: Fosgonimeton Hepatocyte growth factor Potentiators: Dihexa (PNB-0408) Kinase inhibitors: Altiratinib AM7 AMG-458 Amuvatinib BMS-777607...
93 KB (8,729 words) - 06:34, 10 November 2024
HGF (c-Met) Agonists: Fosgonimeton Hepatocyte growth factor Potentiators: Dihexa (PNB-0408) Kinase inhibitors: Altiratinib AM7 AMG-458 Amuvatinib BMS-777607...
121 KB (13,799 words) - 10:33, 13 November 2024
HGF (c-Met) Agonists: Fosgonimeton Hepatocyte growth factor Potentiators: Dihexa (PNB-0408) Kinase inhibitors: Altiratinib AM7 AMG-458 Amuvatinib BMS-777607...
72 KB (6,433 words) - 04:45, 17 November 2024
HGF (c-Met) Agonists: Fosgonimeton Hepatocyte growth factor Potentiators: Dihexa (PNB-0408) Kinase inhibitors: Altiratinib AM7 AMG-458 Amuvatinib BMS-777607...
149 KB (15,703 words) - 16:01, 5 November 2024
HGF (c-Met) Agonists: Fosgonimeton Hepatocyte growth factor Potentiators: Dihexa (PNB-0408) Kinase inhibitors: Altiratinib AM7 AMG-458 Amuvatinib BMS-777607...
42 KB (3,937 words) - 11:44, 15 November 2024
HGF (c-Met) Agonists: Fosgonimeton Hepatocyte growth factor Potentiators: Dihexa (PNB-0408) Kinase inhibitors: Altiratinib AM7 AMG-458 Amuvatinib BMS-777607...
14 KB (1,693 words) - 18:18, 18 October 2024
HGF (c-Met) Agonists: Fosgonimeton Hepatocyte growth factor Potentiators: Dihexa (PNB-0408) Kinase inhibitors: Altiratinib AM7 AMG-458 Amuvatinib BMS-777607...
10 KB (600 words) - 04:23, 25 October 2024
circulation by the liver, with a half-life of approximately 4 minutes. Dihexa is an orally active, centrally penetrant small-molecule compound that directly...
23 KB (2,635 words) - 06:03, 24 August 2024
HGF (c-Met) Agonists: Fosgonimeton Hepatocyte growth factor Potentiators: Dihexa (PNB-0408) Kinase inhibitors: Altiratinib AM7 AMG-458 Amuvatinib BMS-777607...
27 KB (3,061 words) - 16:55, 20 November 2024
HGF (c-Met) Agonists: Fosgonimeton Hepatocyte growth factor Potentiators: Dihexa (PNB-0408) Kinase inhibitors: Altiratinib AM7 AMG-458 Amuvatinib BMS-777607...
71 KB (6,702 words) - 05:32, 9 August 2024
HGF (c-Met) Agonists: Fosgonimeton Hepatocyte growth factor Potentiators: Dihexa (PNB-0408) Kinase inhibitors: Altiratinib AM7 AMG-458 Amuvatinib BMS-777607...
18 KB (1,573 words) - 05:19, 15 October 2024
HGF (c-Met) Agonists: Fosgonimeton Hepatocyte growth factor Potentiators: Dihexa (PNB-0408) Kinase inhibitors: Altiratinib AM7 AMG-458 Amuvatinib BMS-777607...
27 KB (3,078 words) - 19:34, 17 October 2024
HGF (c-Met) Agonists: Fosgonimeton Hepatocyte growth factor Potentiators: Dihexa (PNB-0408) Kinase inhibitors: Altiratinib AM7 AMG-458 Amuvatinib BMS-777607...
35 KB (4,575 words) - 09:00, 2 November 2024
HGF (c-Met) Agonists: Fosgonimeton Hepatocyte growth factor Potentiators: Dihexa (PNB-0408) Kinase inhibitors: Altiratinib AM7 AMG-458 Amuvatinib BMS-777607...
4 KB (241 words) - 07:09, 23 October 2024
HGF (c-Met) Agonists: Fosgonimeton Hepatocyte growth factor Potentiators: Dihexa (PNB-0408) Kinase inhibitors: Altiratinib AM7 AMG-458 Amuvatinib BMS-777607...
17 KB (1,708 words) - 22:30, 15 October 2024
HGF (c-Met) Agonists: Fosgonimeton Hepatocyte growth factor Potentiators: Dihexa (PNB-0408) Kinase inhibitors: Altiratinib AM7 AMG-458 Amuvatinib BMS-777607...
20 KB (1,566 words) - 08:58, 12 August 2024
HGF (c-Met) Agonists: Fosgonimeton Hepatocyte growth factor Potentiators: Dihexa (PNB-0408) Kinase inhibitors: Altiratinib AM7 AMG-458 Amuvatinib BMS-777607...
14 KB (1,689 words) - 01:31, 19 August 2024
HGF (c-Met) Agonists: Fosgonimeton Hepatocyte growth factor Potentiators: Dihexa (PNB-0408) Kinase inhibitors: Altiratinib AM7 AMG-458 Amuvatinib BMS-777607...
13 KB (1,177 words) - 01:44, 4 November 2024
HGF (c-Met) Agonists: Fosgonimeton Hepatocyte growth factor Potentiators: Dihexa (PNB-0408) Kinase inhibitors: Altiratinib AM7 AMG-458 Amuvatinib BMS-777607...
28 KB (3,078 words) - 07:46, 3 June 2024
HGF (c-Met) Agonists: Fosgonimeton Hepatocyte growth factor Potentiators: Dihexa (PNB-0408) Kinase inhibitors: Altiratinib AM7 AMG-458 Amuvatinib BMS-777607...
10 KB (1,179 words) - 18:31, 8 August 2024
HGF (c-Met) Agonists: Fosgonimeton Hepatocyte growth factor Potentiators: Dihexa (PNB-0408) Kinase inhibitors: Altiratinib AM7 AMG-458 Amuvatinib BMS-777607...
6 KB (596 words) - 05:15, 1 January 2024
HGF (c-Met) Agonists: Fosgonimeton Hepatocyte growth factor Potentiators: Dihexa (PNB-0408) Kinase inhibitors: Altiratinib AM7 AMG-458 Amuvatinib BMS-777607...
64 KB (7,432 words) - 08:21, 28 October 2024
HGF (c-Met) Agonists: Fosgonimeton Hepatocyte growth factor Potentiators: Dihexa (PNB-0408) Kinase inhibitors: Altiratinib AM7 AMG-458 Amuvatinib BMS-777607...
23 KB (1,837 words) - 19:36, 11 November 2024
HGF (c-Met) Agonists: Fosgonimeton Hepatocyte growth factor Potentiators: Dihexa (PNB-0408) Kinase inhibitors: Altiratinib AM7 AMG-458 Amuvatinib BMS-777607...
73 KB (6,455 words) - 04:22, 2 November 2024
HGF (c-Met) Agonists: Fosgonimeton Hepatocyte growth factor Potentiators: Dihexa (PNB-0408) Kinase inhibitors: Altiratinib AM7 AMG-458 Amuvatinib BMS-777607...
24 KB (2,882 words) - 16:31, 25 October 2024
HGF (c-Met) Agonists: Fosgonimeton Hepatocyte growth factor Potentiators: Dihexa (PNB-0408) Kinase inhibitors: Altiratinib AM7 AMG-458 Amuvatinib BMS-777607...
39 KB (3,854 words) - 21:20, 3 September 2024
HGF (c-Met) Agonists: Fosgonimeton Hepatocyte growth factor Potentiators: Dihexa (PNB-0408) Kinase inhibitors: Altiratinib AM7 AMG-458 Amuvatinib BMS-777607...
21 KB (1,640 words) - 06:51, 18 September 2024
HGF (c-Met) Agonists: Fosgonimeton Hepatocyte growth factor Potentiators: Dihexa (PNB-0408) Kinase inhibitors: Altiratinib AM7 AMG-458 Amuvatinib BMS-777607...
43 KB (4,651 words) - 13:41, 27 July 2024