domain-containing protein 1 (EPAS1, also known as hypoxia-inducible factor-2alpha (HIF-2α)) is a protein that is encoded by the EPAS1 gene in mammals. It is...
22 KB (2,683 words) - 16:03, 22 August 2024
Per-Arnt-Sim (PAS) domain protein 1 (EPAS1). It was found that one single-nucleotide polymorphism (SNP) at EPAS1 shows a 78% frequency difference between...
52 KB (5,651 words) - 22:13, 16 July 2024
continents. Tibetan humans and Tibetan domestic dogs share a genetic mutation in EPAS1, but it has not been seen in Andean humans. Tardigrades live over the entire...
52 KB (5,493 words) - 19:57, 3 August 2024
deeply-diverged from modern Holarctic wolves and dogs has contributed the EPAS1 allele found in both Himalayan wolves and dogs, and this allows them to...
20 KB (2,382 words) - 01:42, 27 August 2024
that make Tibetans' bodies well-suited for high-altitudes, including the EPAS1 gene, also referred to as the "super-athlete gene", which regulates the...
49 KB (4,959 words) - 09:17, 6 September 2024
brown eyes. The Denisovan genome also contains a variant region around the EPAS1 gene that in Tibetans assists with adaptation to low oxygen levels at high...
71 KB (7,393 words) - 09:18, 30 August 2024
factors that make Tibetan bodies well-suited for high altitudes, including EPAS1, referred to as the "super-athlete gene," that regulates the body's production...
45 KB (5,072 words) - 14:54, 8 September 2024
alleles' high mutation rate. Tibetan people received an advantageous EGLN1 and EPAS1 gene variant, associated with hemoglobin concentration and response to hypoxia...
91 KB (11,130 words) - 11:57, 20 July 2024
For example, in 2010, his research group discovered the variant in the EPAS1 gene that allows Tibetans to live at high altitudes. His research has also...
5 KB (220 words) - 13:51, 4 July 2024
n-Myc MXD4 TCF4 Group C bHLH-PAS AhR AHRR ARNT ARNTL ARNTL2 CLOCK HIF 1A EPAS1 3A NPAS 1 2 3 PER 1 2 3 Period SIM 1 2 Group D BHLH 2 3 9 Pho4 ID 1 2 3...
42 KB (4,829 words) - 16:45, 1 August 2024
ENSG00000163508 T-box Known motif – High-throughput in vitro [202] WTCACACCTH EPAS1 ENSG00000116016 bHLH Known motif – In vivo/Misc source [203] VDACGTGHH ERF...
374 KB (81 words) - 02:10, 23 September 2023
n-Myc MXD4 TCF4 Group C bHLH-PAS AhR AHRR ARNT ARNTL ARNTL2 CLOCK HIF 1A EPAS1 3A NPAS 1 2 3 PER 1 2 3 Period SIM 1 2 Group D BHLH 2 3 9 Pho4 ID 1 2 3...
17 KB (2,005 words) - 23:01, 20 August 2024
contributed 39% to the Himalayan wolf's nuclear genome, and contributed the EPAS1 allele which can be found in both Himalayan wolves and dogs which allows...
55 KB (5,583 words) - 20:26, 27 July 2024
n-Myc MXD4 TCF4 Group C bHLH-PAS AhR AHRR ARNT ARNTL ARNTL2 CLOCK HIF 1A EPAS1 3A NPAS 1 2 3 PER 1 2 3 Period SIM 1 2 Group D BHLH 2 3 9 Pho4 ID 1 2 3...
17 KB (1,854 words) - 04:22, 19 August 2024
n-Myc MXD4 TCF4 Group C bHLH-PAS AhR AHRR ARNT ARNTL ARNTL2 CLOCK HIF 1A EPAS1 3A NPAS 1 2 3 PER 1 2 3 Period SIM 1 2 Group D BHLH 2 3 9 Pho4 ID 1 2 3...
20 KB (2,042 words) - 04:48, 6 January 2024
Tibetans evolving over 3,000 years to have high proportions of an allele of EPAS1 that is adaptive to high altitudes. Other evolution is related to endemic...
265 KB (26,537 words) - 16:22, 26 August 2024
n-Myc MXD4 TCF4 Group C bHLH-PAS AhR AHRR ARNT ARNTL ARNTL2 CLOCK HIF 1A EPAS1 3A NPAS 1 2 3 PER 1 2 3 Period SIM 1 2 Group D BHLH 2 3 9 Pho4 ID 1 2 3...
39 KB (4,859 words) - 19:32, 22 August 2024
n-Myc MXD4 TCF4 Group C bHLH-PAS AhR AHRR ARNT ARNTL ARNTL2 CLOCK HIF 1A EPAS1 3A NPAS 1 2 3 PER 1 2 3 Period SIM 1 2 Group D BHLH 2 3 9 Pho4 ID 1 2 3...
41 KB (4,385 words) - 21:28, 21 August 2024
n-Myc MXD4 TCF4 Group C bHLH-PAS AhR AHRR ARNT ARNTL ARNTL2 CLOCK HIF 1A EPAS1 3A NPAS 1 2 3 PER 1 2 3 Period SIM 1 2 Group D BHLH 2 3 9 Pho4 ID 1 2 3...
29 KB (3,402 words) - 07:08, 20 May 2024
as the Sherpas from Nepal is believed to have inherited an allele called EPAS1, which allows them to breathe easily at high altitudes, from the Denisovans...
102 KB (11,865 words) - 00:53, 9 August 2024
and wolves living in the Himalayas and on the Tibetan plateau carry the EPAS1 allele that is associated with high-altitude oxygen adaptation, which has...
172 KB (20,424 words) - 00:19, 6 September 2024
n-Myc MXD4 TCF4 Group C bHLH-PAS AhR AHRR ARNT ARNTL ARNTL2 CLOCK HIF 1A EPAS1 3A NPAS 1 2 3 PER 1 2 3 Period SIM 1 2 Group D BHLH 2 3 9 Pho4 ID 1 2 3...
75 KB (8,057 words) - 04:44, 25 July 2024
n-Myc MXD4 TCF4 Group C bHLH-PAS AhR AHRR ARNT ARNTL ARNTL2 CLOCK HIF 1A EPAS1 3A NPAS 1 2 3 PER 1 2 3 Period SIM 1 2 Group D BHLH 2 3 9 Pho4 ID 1 2 3...
6 KB (514 words) - 21:03, 25 November 2022
n-Myc MXD4 TCF4 Group C bHLH-PAS AhR AHRR ARNT ARNTL ARNTL2 CLOCK HIF 1A EPAS1 3A NPAS 1 2 3 PER 1 2 3 Period SIM 1 2 Group D BHLH 2 3 9 Pho4 ID 1 2 3...
58 KB (6,133 words) - 05:31, 13 July 2024
n-Myc MXD4 TCF4 Group C bHLH-PAS AhR AHRR ARNT ARNTL ARNTL2 CLOCK HIF 1A EPAS1 3A NPAS 1 2 3 PER 1 2 3 Period SIM 1 2 Group D BHLH 2 3 9 Pho4 ID 1 2 3...
24 KB (2,820 words) - 05:34, 10 July 2024
n-Myc MXD4 TCF4 Group C bHLH-PAS AhR AHRR ARNT ARNTL ARNTL2 CLOCK HIF 1A EPAS1 3A NPAS 1 2 3 PER 1 2 3 Period SIM 1 2 Group D BHLH 2 3 9 Pho4 ID 1 2 3...
19 KB (2,243 words) - 23:46, 9 September 2024
n-Myc MXD4 TCF4 Group C bHLH-PAS AhR AHRR ARNT ARNTL ARNTL2 CLOCK HIF 1A EPAS1 3A NPAS 1 2 3 PER 1 2 3 Period SIM 1 2 Group D BHLH 2 3 9 Pho4 ID 1 2 3...
16 KB (2,049 words) - 05:58, 25 October 2023
n-Myc MXD4 TCF4 Group C bHLH-PAS AhR AHRR ARNT ARNTL ARNTL2 CLOCK HIF 1A EPAS1 3A NPAS 1 2 3 PER 1 2 3 Period SIM 1 2 Group D BHLH 2 3 9 Pho4 ID 1 2 3...
35 KB (3,818 words) - 10:04, 26 August 2024
n-Myc MXD4 TCF4 Group C bHLH-PAS AhR AHRR ARNT ARNTL ARNTL2 CLOCK HIF 1A EPAS1 3A NPAS 1 2 3 PER 1 2 3 Period SIM 1 2 Group D BHLH 2 3 9 Pho4 ID 1 2 3...
15 KB (1,739 words) - 14:34, 15 July 2024
n-Myc MXD4 TCF4 Group C bHLH-PAS AhR AHRR ARNT ARNTL ARNTL2 CLOCK HIF 1A EPAS1 3A NPAS 1 2 3 PER 1 2 3 Period SIM 1 2 Group D BHLH 2 3 9 Pho4 ID 1 2 3...
57 KB (6,717 words) - 23:11, 17 August 2024