Electrophilic aromatic substitution (SEAr) is an organic reaction in which an atom that is attached to an aromatic system (usually hydrogen) is replaced...

compounds can undergo electrophilic substitution as well. In electrophilic substitution in aromatic compounds, an atom appended to the aromatic ring, usually...

Electrophiles are involved in electrophilic substitution reactions, particularly in electrophilic aromatic substitutions. In this example, the benzene...

In electrophilic aromatic substitution reactions, existing substituent groups on the aromatic ring influence the overall reaction rate or have a directing...

A nucleophilic aromatic substitution (SNAr) is a substitution reaction in organic chemistry in which the nucleophile displaces a good leaving group, such...

the same ring position in an intermediate compound in an electrophilic aromatic substitution. Trimethylsilyl, tert-butyl, and isopropyl groups can form...

flame, due to high C:H ratio Undergo electrophilic substitution reactions and nucleophilic aromatic substitutions Arenes are typically split into two categories...

chemistry, an electrophilic aromatic halogenation is a type of electrophilic aromatic substitution. This organic reaction is typical of aromatic compounds...

Electrophilic attack to an aromatic system results in electrophilic aromatic substitution rather than an addition reaction. Typical electrophilic additions...

to prevent electrophilic aromatic substitution. They can also be installed as directing groups to affect the position where a substitution may take place...

Electron-withdrawing groups also tend to reduce Lewis basicity. Electrophilic aromatic substitution is famously affected by EWGs. The effect is transmitted by...

seven years later by J. J. Thomson. Second, he is describing electrophilic aromatic substitution, proceeding (third) through a Wheland intermediate, in which...

caused by substitution of anilines to become weaker bases, compared to substitution of isomers in the meta and para position. Electrophilic aromatic substitution...

of aromatic compounds. It is toxic to humans. Relative to benzene, aniline is "electron-rich". It thus participates more rapidly in electrophilic aromatic...

Regioselectivity is strongly affected by substituents on aromatic rings (see electrophilic aromatic substitution). For example, nitration of nitrobenzene gives...

NO+2, which is important in nitration reactions involving electrophilic aromatic substitution. This type of reaction, where protonation occurs on an oxygen...

aromatic ring. Friedel–Crafts reactions are of two main types: alkylation reactions and acylation reactions. Both proceed by electrophilic aromatic substitution...

Directed ortho metalation (DoM) is an adaptation of electrophilic aromatic substitution in which electrophiles attach themselves exclusively to the ortho-...

cyclohexadienyl cation that appears as a reactive intermediate in electrophilic aromatic substitution. For historic reasons this complex is also called a Wheland...

The Bischler–Napieralski reaction is an intramolecular electrophilic aromatic substitution reaction that allows for the cyclization of β-arylethylamides...

θ-Hexachlorocyclohexane Chlorination of benzene under electrophilic aromatic substitution conditions (Cl2/FeCl3 or Cl2/AlCl3) produces chlorobenzene...

of nitro groups in aromatic compounds retards electrophilic aromatic substitution but facilitates nucleophilic aromatic substitution. Nitro groups are...

Quelet reaction is an example of a larger class of reaction, electrophilic aromatic substitution. The reaction is named after its creator R. Quelet, who first...

associated with electrophilic aromatic substitution reactions and the products follow the arene substitution pattern. So, a given substituted phenyl compound...

complementary to electrophilic aromatic substitution. The Sandmeyer reaction is an example of a radical-nucleophilic aromatic substitution (SRNAr). The radical...

classic patterns of electrophilic aromatic substitution (for example, a meta nitro group inhibits the reaction), although substitution ortho to the amine...

common reactions of benzene involve substitution of a proton by other groups. Electrophilic aromatic substitution is a general method of derivatizing...

greater extent. Therefore, electrophilic aromatic substitution is more difficult while nucleophilic aromatic substitution is facilitated. An example of...

rearrangement Substitution reaction Electrophilic aromatic substitution Nucleophilic aromatic substitution Electrophilic substitution Nucleophilic substitution SN1...

compound (R−N≡N+) and another aromatic compound that produces an azo compound (R−N=N−R’). In this electrophilic aromatic substitution reaction, the aryldiazonium...