Elevated alkaline phosphatase occurs when levels of alkaline phosphatase (ALP) exceed the reference range. This group of enzymes has a low substrate specificity...
15 KB (1,662 words) - 21:45, 20 June 2024
The enzyme alkaline phosphatase (ALP, alkaline phenyl phosphatase, also abbreviated PhoA) is a phosphatase with the physiological role of dephosphorylating...
54 KB (6,115 words) - 02:37, 14 February 2025
first clinical manifestation of Paget's disease is usually an elevated alkaline phosphatase in the blood. Paget's disease may be diagnosed using one or...
41 KB (4,772 words) - 19:55, 23 August 2024
may be associated with elevated alkaline phosphatase levels, while others (such as Ewing sarcoma) can be associated with elevated erythrocyte sedimentation...
37 KB (4,086 words) - 01:11, 3 January 2025
obesity); it also has cytoplasmic clearing and cell swelling. Elevated alkaline phosphatase (ALP) Mallory body Non-alcoholic fatty liver disease Steatohepatitis...
2 KB (132 words) - 21:12, 29 July 2023
(cholestatic pattern). This is often displayed by markedly elevated alkaline phosphatase levels and milder or no elevation in liver enzyme levels. Results...
143 KB (16,275 words) - 07:40, 9 February 2025
Malabsorption Fat-soluble vitamin deficiencies Elevated alkaline phosphatase Elevated gamma-glutamyltransferase Elevated conjugated bilirubin In fetal and neonatal...
3 KB (271 words) - 21:38, 2 November 2024
depleted Elevated aspartate aminotransferase (AST), bilirubin and lactate dehydrogenase (LDH) Hypercalcemia and elevated alkaline phosphatase due to increased...
29 KB (2,927 words) - 21:22, 1 June 2024
Alanine transaminase (redirect from Elevated ALT)
For example, elevated ALT levels due to hepatocyte damage can be distinguished from bile duct problems by measuring alkaline phosphatase. Also, myopathy-related...
13 KB (1,379 words) - 21:20, 17 January 2025
is shown to target the major symptoms of XLH by decreasing elevated alkaline phosphatase and normalizing severe hypophosphatemia, leading to substantial...
28 KB (2,784 words) - 21:38, 29 November 2024
titer of anti-mitochondrial antibody (AMA) against PDC-E2 and elevated alkaline phosphatase persisting for 6+ months. Ursodeoxycholic acid (UDCA) is an...
113 KB (12,756 words) - 21:16, 10 February 2025
ALPL (redirect from Tissue-nonspecific alkaline phosphatase)
Alkaline phosphatase, tissue-nonspecific isozyme (TNAP) is an enzyme that in humans is encoded by the ALPL gene. There are at least four distinct but related...
19 KB (2,329 words) - 12:56, 2 January 2025
conditions linked to the biliary tract (gamma-glutamyl transferase and alkaline phosphatase). Because some of these tests do not measure function, it is more...
25 KB (2,908 words) - 02:50, 17 December 2024
All patients with RVCL develop kidney and liver disease, with elevated alkaline phosphatase. Some patients develop bone lesions (osteonecrosis) as well...
17 KB (1,801 words) - 21:49, 17 January 2025
characterized by severe mental retardation, considerably elevated serum levels of alkaline phosphatase, hypoplastic terminal phalanges, and distinct facial...
7 KB (595 words) - 18:17, 30 October 2024
anemia. Typical clinical features include jaundice, elevated blood levels of alkaline phosphatase, calcinosis cutis, telangiectasias, and pruritus. This...
3 KB (193 words) - 02:53, 13 January 2024
250 mg/kg only a slight loss of weight, and with 250 mg/kg mildly elevated Alkaline phosphatase and Gamma-GT. Studies in dogs revealed no toxicity relevant...
83 KB (9,147 words) - 03:06, 14 January 2025
Hyperparathyroidism (section Alkaline phosphatase)
serum phosphate levels are generally elevated because of kidney disease.[citation needed] Alkaline phosphatase levels are usually high in hyperparathyroidism...
51 KB (5,194 words) - 04:49, 11 February 2025
universally elevated. Alkaline phosphatase is often elevated in pregnancy due to production from the placenta, but may be additionally elevated. Other abnormalities...
17 KB (1,954 words) - 12:21, 20 October 2024
established hepatotoxic effects including increased liver weight, elevated alkaline phosphatase activity and reduced cholesterol and lipid levels. Increased...
24 KB (2,515 words) - 05:55, 22 November 2024
Hypophosphatasia (/ˌhaɪpoʊˈfɒsfeɪtˌeɪʒə/; also called deficiency of alkaline phosphatase, phosphoethanolaminuria, or Rathbun's syndrome; sometimes abbreviated...
41 KB (4,499 words) - 20:15, 14 January 2025
low-normal serum calcium, moderately low serum phosphate, elevated serum alkaline phosphatase, and low serum 1,25 dihydroxy-vitamin D levels, hyperphosphaturia...
12 KB (1,194 words) - 13:56, 13 November 2024
depression, and encephalopathy, low white blood cell levels, elevated alkaline phosphatase, and idiopathic intracranial hypertension that can cause headache...
20 KB (1,619 words) - 04:07, 17 January 2025
product of the breast cancer-associated MUC1 gene. Elevated CA15-3, in conjunction with alkaline phosphatase (ALP), was found to be associated with an increased...
2 KB (275 words) - 19:38, 30 June 2024
5'-nucleotidase (redirect from 5'-adenylic phosphatase)
liver problems. The combined assays of serum 5'nucleotisase and alkaline phosphatase (AP) activities are extremely helpful in differential diagnosis since...
15 KB (1,598 words) - 10:03, 25 November 2024
of renal osteodystrophy Elevated serum alkaline phosphatase (due to an increase in compensatory osteoblast activity) Elevated parathyroid hormone (due...
16 KB (1,666 words) - 16:03, 20 November 2024
Biochemical studies reveal hypophosphatemia (low blood phosphate), elevated alkaline phosphatase and low serum 1,25 dihydroxyvitamin D levels. Routine laboratory...
11 KB (1,164 words) - 11:31, 5 February 2025
nilutamide, and bicalutamide), there has been no evidence of hepatotoxicity or elevated liver enzymes in association with enzalutamide treatment in clinical trials...
85 KB (8,727 words) - 01:24, 2 September 2024
forms typically seen in acute leukemia. Serum leukocyte alkaline phosphatase is normal or elevated in leukemoid reaction, but is depressed in chronic myelogenous...
5 KB (469 words) - 21:40, 19 October 2024
include dizziness, elevated liver enzymes, vomiting, and elevated alkaline phosphatase. Common (> 1%) side effects include nausea, elevated blood lipids, fever...
18 KB (2,078 words) - 20:39, 3 June 2024