• Thumbnail for Elexacaftor
    Elexacaftor is a medication that acts as cystic fibrosis transmembrane conductance regulator (CFTR) corrector. It is available in a single pill with ivacaftor...
    7 KB (286 words) - 14:34, 17 May 2024
  • Elexacaftor/tezacaftor/ivacaftor, sold under the brand names Trikafta and Kaftrio, is a fixed-dose combination medication used to treat cystic fibrosis...
    38 KB (3,107 words) - 08:02, 24 June 2024
  • Thumbnail for Tezacaftor
    Symdeko. It was approved by the U.S. FDA in 2018. The combination of elexacaftor, tezacaftor, and ivacaftor is being sold as Trikafta. In 2019, the U...
    11 KB (724 words) - 19:14, 30 November 2023
  • Thumbnail for Ivacaftor
    combination medications, lumacaftor/ivacaftor, tezacaftor/ivacaftor, and elexacaftor/tezacaftor/ivacaftor which are used to treat people with cystic fibrosis...
    34 KB (3,170 words) - 13:50, 20 September 2024
  • Thumbnail for Cystic fibrosis
    treat people with the F508del mutation. In 2019, the combination drug elexacaftor/ivacaftor/tezacaftor, marketed as Trikafta,was approved for CF patients...
    161 KB (18,151 words) - 09:04, 27 September 2024
  • lumacaftor R07AX31 Ivacaftor and tezacaftor R07AX32 Ivacaftor, tezacaftor and elexacaftor "ATC (Anatomical Therapeutic Chemical Classification System) – Synopsis"...
    1,000 bytes (237 words) - 06:04, 4 January 2021
  • Pembrolizumab Merck endometrial carcinoma Lenvatinib Eisai endometrial carcinoma Elexacaftor/tezacaftor/ivacaftor Vertex Pharmaceuticals cystic fibrosis Zanubrutinib...
    34 KB (180 words) - 22:09, 8 April 2024
  • Thumbnail for Vertex Pharmaceuticals
    filed with it, the FDA approved Vertex's Triple-combo therapy Trikafta (elexacaftor/tezacaftor/ivacaftor) for patients 12 and older with at least one F508del...
    37 KB (3,631 words) - 14:27, 21 September 2024
  • Thumbnail for Cystic fibrosis and race
    some approved CFTR modulators for specific mutations. One such drug is elexacaftor/tezacaftor/ivacaftor. However, the cost of CFTR modulators is high. In...
    34 KB (3,174 words) - 07:09, 22 June 2024
  • Most recently, Grootenhuis's team discovered Tezacaftor (VX-661) and Elexacaftor (VX-445), which in combination with Ivacaftor are the components of Trikafta...
    10 KB (964 words) - 21:17, 14 September 2024
  • the discovery of tezacaftor and elexacaftor, 2 other correctors of the CFTR protein. The triple combination elexacaftor/tezacaftor/ivacaftor was approved...
    19 KB (1,496 words) - 21:41, 21 June 2024