• Elongase is a generic term for an enzyme that extends the length of fatty acid. The nomenclature is not applied rigorously. Often, elongase refers to...
    3 KB (381 words) - 16:07, 20 May 2024
  • Thumbnail for Docosahexaenoic acid
    elongation reactions, catalyzed by the sequential action of desaturase and elongase enzymes. This pathway, originally identified in Thraustochytrium, applies...
    30 KB (3,189 words) - 02:11, 21 September 2024
  • Thumbnail for Eicosapentaenoic acid
    elongation reactions, catalyzed by the sequential action of desaturase and elongase enzymes. This pathway, originally identified in Thraustochytrium, applies...
    28 KB (3,000 words) - 23:38, 22 September 2024
  • Thumbnail for Alachlor
    alachlor are currently registered in the United States. Its mode of action is elongase inhibition, and inhibition of geranylgeranyl pyrophosphate (GGPP) cyclisation...
    10 KB (945 words) - 18:11, 12 September 2024
  • 18:4-n3) respectively. In the biosynthesis of essential fatty acids, an elongase alternates with various desaturases (for example, Δ6-desaturase) repeatedly...
    17 KB (1,847 words) - 02:17, 29 June 2024
  • derived from linoleic acid. They both utilize the same desaturase and elongase proteins in order to synthesize inflammatory regulatory proteins. The products...
    115 KB (12,761 words) - 02:00, 21 September 2024
  • Thumbnail for Acetochlor
    class of herbicides known as chloroacetanilides. Its mode of action is elongase inhibition, and inhibition of geranylgeranyl pyrophosphate (GGPP) cyclization...
    7 KB (596 words) - 16:41, 28 May 2024
  • acyl-CoA elongase, C18-CoA elongase, and stearoyl-CoA elongase. Bessoule JJ, Lessire R, Cassagne C (1989). "Partial purification of the acyl-CoA elongase of...
    3 KB (230 words) - 14:32, 26 August 2023
  • Thumbnail for Plant cuticle
    An important catalyzer thought to be in this process is the fatty acid elongase (FAE) complex. To form cuticular wax components, VLCFAs are modified through...
    9 KB (1,148 words) - 16:36, 22 October 2024
  • Thumbnail for ELOVL4
    by the ELOVL4 gene. ELOVL4 is a member of a large family of fatty acid elongases (ELO) that catalyzes the rate-limiting step in the elongation of long...
    20 KB (2,114 words) - 11:42, 27 January 2024
  • Thumbnail for Chromosome 6
    Desmoplakin gene linked to cardiomyopathy (6p24.3) ELOVL5: ELOVL fatty acid elongase 5 (6p12.1) FBXO9: F-box protein 9 (6p12.1) FOXP4-AS1: encoding protein...
    35 KB (2,420 words) - 20:57, 24 August 2024
  • "A Saccharomyces cerevisiae gene required for heterologous fatty acid elongase activity encodes a microsomal beta-keto-reductase". The Journal of Biological...
    2 KB (249 words) - 10:35, 5 January 2024
  • Thumbnail for Isochrysis galbana
    "Expression of the Isochrysis C18-Δ9 Polyunsaturated Fatty Acid Specific Elongase Component Alters Arabidopsis Glycerolipid Profiles". Plant Physiology....
    4 KB (402 words) - 05:51, 1 April 2024
  • Thumbnail for Rapeseed oil
    napus L.) results from a deletion of four base pairs in the fatty acid elongase 1 gene". Theoretical and Applied Genetics. 116 (4): 491–499. doi:10...
    48 KB (6,043 words) - 15:40, 14 November 2024
  • adrenoleukodystrophy Jakobsson, Andreas; Westerberg, Rolf; Jacobsson, Anders "Fatty acid elongases in mammals: their regulation and roles in metabolism" Progress in Lipid...
    4 KB (445 words) - 22:47, 26 November 2023
  • trans-2,3-dehydroacyl-CoA + NADPH + H+ This is the fourth component of the elongase, a microsomal protein complex responsible for extending palmitoyl-CoA and...
    3 KB (299 words) - 16:18, 26 August 2023
  • Thumbnail for ELOVL5
    Identifiers Aliases ELOVL5, HELO1, SCA38, dJ483K16.1, ELOVL fatty acid elongase 5 External IDs OMIM: 611805; MGI: 1916051; HomoloGene: 41449; GeneCards:...
    4 KB (495 words) - 22:50, 3 March 2023
  • Thumbnail for Essential fatty acid interactions
    (18:3 ω-3) contributes by displacing linoleic acid (18:2 ω-6) from the elongase and desaturase enzymes that produce AA. EPA inhibits phospholipase A2's...
    27 KB (2,975 words) - 06:52, 2 November 2024
  • very-long-chain trans-2,3-dehydroacyl-CoA + H2O This is the third component of the elongase. Bach L, Michaelson LV, Haslam R, Bellec Y, Gissot L, Marion J, Da Costa...
    2 KB (214 words) - 16:18, 26 August 2023
  • Thumbnail for Secondary metabolite
    engineered biosynthetic pathways for nonnatural C60 carotenoids using C5-elongases and C50-cyclases in Escherichia coli". Scientific Reports. 9 (1): 2982...
    36 KB (3,720 words) - 16:45, 5 November 2024
  • Thumbnail for Metolachlor
    grasses. Metolachlor was developed by Ciba-Geigy. Its acts by inhibition of elongases and of the geranylgeranyl pyrophosphate (GGPP) cyclases, which are part...
    10 KB (908 words) - 15:00, 6 November 2024
  • Thumbnail for Ketoacyl synthase
    common enzymes in this family are 3-ketoacyl-CoA synthases, fatty acid elongases and very long-chain fatty acid condensing enzymes. The most common general...
    17 KB (2,238 words) - 22:10, 18 August 2023
  • Thumbnail for Hortaea werneckii
    (March 2009). "The expressions of Delta 9-, Delta 12-desaturases and an elongase by the extremely halotolerant black yeast Hortaea werneckii are salt dependent"...
    9 KB (971 words) - 14:50, 18 August 2024
  • Thumbnail for Sciadonic acid
    unsaturated fatty acid (20:2, n-6) When AL10 is co-expressed with a Δ9-elongase the biosynthesis of sciadonic acid is achieved in transgenic plants. A...
    10 KB (1,101 words) - 09:33, 23 March 2024
  • Thumbnail for N-Acylethanolamine
    fatty acid) → γ-linolenic acid (GLA: C18H30O2; 18:3-n6) → Δ6-specific elongase (introducing two carbons and four hydrogens) → Dihomo-gamma-linolenic acid...
    187 KB (20,412 words) - 12:43, 20 October 2024
  • very-long-chain 3-oxoacyl-CoA + CO2 + coenzyme A This is the first component of the elongase, a microsomal protein complex responsible for extending palmitoyl-CoA and...
    4 KB (498 words) - 23:56, 15 February 2024
  • lycopaoctaene synthase EC 2.5.1.149: lycopene elongase/hydratase (flavuxanthin-forming) EC 2.5.1.150: lycopene elongase/hydratase (dihydrobisanhydrobacterioruberin-forming)...
    215 KB (21,664 words) - 23:41, 8 May 2024
  • Thumbnail for Zootermopsis nevadensis
    by the abundance of four long chain polyunsaturated alkenes. From 16 elongases and 10 desaturases found in Z. nevadensis one of each group is highly...
    13 KB (1,608 words) - 08:57, 16 October 2024
  • Thumbnail for Ascoviridae
    caspase, a cathepsin B, several kinases, E3 ubiquitin ligases, a fatty acid elongase, a sphingomyelinase, a phosphate acyltransferase and a patatin-like phospholipase...
    7 KB (674 words) - 05:32, 13 March 2024
  • Thumbnail for Rev-ErbA alpha
    apolipoproteins, sterol regulatory element binding protein, and the fatty acid elongase elovl3 through its repressional activity In addition, the silencing of...
    36 KB (4,270 words) - 10:03, 25 July 2024