• Thumbnail for FBXL5
    F-box/LRR-repeat protein 5 is a protein that in humans is encoded by the FBXL5 gene. This gene encodes a member of the F-box protein family which is characterized...
    6 KB (724 words) - 21:41, 15 June 2024
  • Thumbnail for F-box protein
    human cells, under high-iron conditions, two iron atoms stabilise the F-Box FBXL5 and then the complex mediates the ubiquitination of IRP2. F-box protein...
    6 KB (735 words) - 13:31, 3 December 2023
  • HGNC:13598 Q9UKC9 5499 FBXL3 HGNC:13599 Q9UKT7 5500 FBXL4 HGNC:13601 Q9UKA2 5501 FBXL5 HGNC:13602 Q9UKA1 5502 FBXL6 HGNC:13603 Q8N531 5503 FBXL7 HGNC:13604 Q9UJT9...
    277 KB (17 words) - 15:46, 9 May 2024
  • ubiquitinating the F-box and leucine-rich repeat protein 5 (FBXL5) for proteasomal degradation. FBXL5 regulates the stability of the iron regulatory protein...
    27 KB (3,301 words) - 12:04, 3 July 2024
  • Thumbnail for Iron-responsive element-binding protein
    IRP2 degradation in iron-replete cells. IRP2 is regulated by the F-Box FBXL5 which activate the ubiquitination and then the degradation of IRP2. IRP2...
    8 KB (997 words) - 02:27, 18 October 2022