• Thumbnail for Galactokinase
    Galactokinase is an enzyme (phosphotransferase) that facilitates the phosphorylation of α-D-galactose to galactose 1-phosphate at the expense of one molecule...
    14 KB (1,495 words) - 18:04, 11 August 2024
  • Thumbnail for Galactokinase deficiency
    Galactokinase deficiency is an autosomal recessive metabolic disorder marked by an accumulation of galactose and galactitol secondary to the decreased...
    7 KB (723 words) - 19:19, 29 August 2024
  • Thumbnail for Galactosemia
    galactosemia, the enzymes needed for further metabolism of galactose (Galactokinase and galactose-1-phosphate uridyltransferase) are severely diminished...
    19 KB (1,858 words) - 10:28, 12 August 2024
  • Thumbnail for Galactitol
    product of galactose. It has a slightly sweet taste. In people with galactokinase deficiency, a form of galactosemia, excess dulcitol forms in the lens...
    3 KB (128 words) - 12:09, 20 July 2023
  • Thumbnail for Galactose
    pathway. The enzymes are listed in the order of the metabolic pathway: galactokinase (GALK), galactose-1-phosphate uridyltransferase (GALT), and UDP-galactose-4’-epimerase...
    24 KB (2,420 words) - 08:55, 3 September 2024
  • Thumbnail for Galactose-1-phosphate uridylyltransferase deficiency
    indistinguishable from other inborn errors of galactose metabolism, including galactokinase deficiency and galactose epimerase deficiency. Further analysis of metabolites...
    12 KB (1,280 words) - 07:00, 15 April 2024
  • main classes of enzymes). Another example is the conversion of a yeast galactokinase (Gal1) to a transcription factor (Gal3) which can be achieved by an...
    32 KB (3,539 words) - 20:03, 10 August 2024
  • glucose, galactose travels to the liver for conversion to glucose. Galactokinase uses one molecule of ATP to phosphorylate galactose. The phosphorylated...
    20 KB (2,294 words) - 16:30, 29 June 2024
  • Thumbnail for Fructose
    galactose are phosphorylated in the liver by fructokinase (Km= 0.5 mM) and galactokinase (Km = 0.8 mM), respectively. By contrast, glucose tends to pass through...
    52 KB (5,334 words) - 00:01, 27 August 2024
  • Thumbnail for Leloir pathway
    active form in the pathway. Next, α-D-galactose is phosphorylated by galactokinase to galactose 1-phosphate. In the third step, D-galactose-1-phosphate...
    4 KB (339 words) - 17:33, 11 August 2024
  • reduction product of galactose Iditol, a sugar alcohol which accumulates in galactokinase deficiency Mannitol, a sugar alcohol used as a sweetener and medication...
    478 bytes (84 words) - 17:43, 24 September 2020
  • Thumbnail for Chromosome 17
    Voltage-Gated Sodium Channel Subunit Alpha Nav1.4 (17q23.3) GALK1: galactokinase 1 (17q24) KCNJ2: potassium inwardly-rectifying channel, subfamily J...
    26 KB (1,916 words) - 21:48, 21 August 2024
  • Name Enzyme Description galactokinase deficiency Galactokinase Causes cataracts, which form due to the elevation of galactitol that accumulates when galactose...
    3 KB (170 words) - 10:13, 12 August 2024
  • Thumbnail for Ribose
    function on different protein folds: The hexokinase, ribokinase, and galactokinase families of sugar kinases". Protein Science. 2 (1): 31–40. doi:10.1002/pro...
    31 KB (3,186 words) - 09:00, 6 August 2024
  • Thumbnail for Congenital cataract
    test for reducing substance, galactose 1-phosphate uridyltransferase, galactokinase, amino acids - Infectious diseases: TORCH and varicella titers, VDRL...
    10 KB (1,095 words) - 20:59, 30 May 2024
  • and activates them. In yeast cells, the principal targets are GAL1 (galactokinase), GAL10 (UDP-glucose 4-epimerase), and GAL7 (galactose-1-phosphate...
    19 KB (2,205 words) - 12:40, 13 August 2023
  • of cataract among classic galactosemics is markedly less than among galactokinase-deficient patients due to the extremely high levels of galactitol found...
    22 KB (2,717 words) - 08:16, 17 February 2022
  • Thumbnail for Iditol
    Iditol is a sugar alcohol which accumulates in galactokinase deficiency.[citation needed] Idose Aldose reductase L-iditol 2-dehydrogenase "2-Carb-19"...
    2 KB (37 words) - 04:20, 5 November 2023
  • Thumbnail for Phosphofructokinase
    function on different protein folds: the hexokinase, ribokinase, and galactokinase families of sugar kinases". Protein Science. 2 (1): 31–40. doi:10.1002/pro...
    10 KB (1,044 words) - 08:43, 10 June 2024
  • Thumbnail for Luis Federico Leloir
    S2CID 44975916. Trucco, R.E.; Caputto, R; Leloir, L.F.; Mittelman, N (1948). "Galactokinase". Arch. Biochem. 18 (1): 137–146. PMID 18871223. Caputto, R; Leloir...
    26 KB (2,782 words) - 19:37, 7 September 2024
  • Thumbnail for Uridine diphosphate galactose
    hydrolyzed, D-Galactose enters the liver via the bloodstream. There, galactokinase phosphorylates it to galactose-1-phosphate using ATP. This compound...
    4 KB (199 words) - 20:01, 16 May 2024
  • X Y Z See also Health Exercise Nutrition Galactorrhea Galactocoele Galactokinase deficiency Galactorrhea hyperprolactinemia Galactosamine-6-sulfatase...
    10 KB (846 words) - 12:38, 3 March 2024
  • Thumbnail for Transferase
    less severe than classic galactosemia and is caused by a deficiency of galactokinase. Galactosemia renders infants unable to process the sugars in breast...
    60 KB (6,229 words) - 18:27, 8 August 2024
  • binding sites to transport oxygen. The hexokinase, ribokinase, and galactokinase families of sugar kinases have similar enzymatic functions of sugar...
    137 KB (14,871 words) - 19:07, 29 August 2024
  • Thumbnail for GHMP kinase family
    enzymes. Members of this family include homoserine kinases EC 2.7.1.39, galactokinases EC 2.7.1.6, and mevalonate kinasesEC 2.7.1.36. These kinases make up...
    3 KB (309 words) - 10:09, 6 July 2021
  • Thumbnail for Inborn errors of carbohydrate metabolism
    missense mutation in exon 6. A milder form of galactosemia, called Galactokinase deficiency, is caused a lack of the enzyme uridine diphosphate galactose-4-epimerase...
    58 KB (2,792 words) - 22:37, 19 June 2024
  • Thumbnail for François Jacob
    Buttin, G.; Jacob, F.; Monod, J. (1960). "Constituent synthesis of galactokinase following the development of lambda bacteriophages in Escherichia coli...
    21 KB (2,097 words) - 09:36, 9 September 2024
  • Thumbnail for Galactose 1-phosphate
    glucose and uridine diphosphate galactose. It is formed from galactose by galactokinase.The improper metabolism of galactose-1-phosphate is a characteristic...
    4 KB (377 words) - 13:36, 25 April 2024
  • Thumbnail for Galactosamine
    pathway galactosamine is metabolized into galactosamine-1-phosphate (by galactokinase) and UDP-galactosamine (by UDP-galactose uridyltransferase). It is hypothesized...
    4 KB (359 words) - 04:42, 22 February 2023
  • GALK2 may refer to: N-acetylgalactosamine kinase, an enzyme Galactokinase, an enzyme This disambiguation page lists articles associated with the same...
    130 bytes (49 words) - 01:15, 25 January 2020