Galectin-1 is a protein that in humans is encoded by the LGALS1 gene. LGALS1 contains four exons. The galectin-1 protein is 135 amino acids in length and...
8 KB (922 words) - 18:36, 20 November 2023
Galectins are a class of proteins that bind specifically to β-galactoside sugars, such as N-acetyllactosamine (Galβ1-3GlcNAc or Galβ1-4GlcNAc), which...
34 KB (3,864 words) - 01:49, 22 June 2024
Galectin-3 is a protein that in humans is encoded by the LGALS3 gene. Galectin-3 is a member of the lectin family, of which 14 mammalian galectins have...
25 KB (2,839 words) - 08:50, 18 May 2024
used to infect human NSCs (hNSCs) with Galectin-1 which were later transplanted into the damaged tissue. The hGal-1-hNSCs induced better and faster brain...
35 KB (4,177 words) - 02:23, 18 September 2024
glycolysis in these tumors is probably related to their aggressive biology. Galectin-1 in TNBC is a beta-galactosidase-binding protein that shields cancer cells...
28 KB (3,411 words) - 03:40, 14 June 2024
Galectin-9 was first isolated from mouse embryonic kidney in 1997 as a 36 kDa beta-galactoside lectin protein. Human galectin-9 is encoded by the LGALS9...
18 KB (2,173 words) - 06:45, 14 August 2024
how such tumors can be regressed. He also looked at the properties of galectins, and how they show potential for disease. Rabinovich was born in Córdoba...
12 KB (1,339 words) - 23:37, 15 October 2024
Galectin-4 is a protein that in humans is encoded by the LGALS4 gene. The galectins are a family of beta-galactoside-binding proteins implicated in modulating...
12 KB (1,609 words) - 14:15, 29 September 2022
Galectin-3-binding protein is a protein that in humans is encoded by the LGALS3BP gene. The galectins are a family of beta-galactoside-binding proteins...
9 KB (1,111 words) - 20:42, 13 October 2022
Galectin-8 is a protein of the galectin family that in humans is encoded by the LGALS8 gene. This gene encodes a member of the galectin family. Galectins...
12 KB (1,446 words) - 10:25, 9 October 2024
Klotho causes cell-surface retention of TRPV5 channel via binding to galectin-1". Proceedings of the National Academy of Sciences of the United States...
16 KB (1,840 words) - 09:33, 21 September 2024
such as PD-L1 and PD-L2, heme oxygenase 1, HLA-G, CD95L, TNF-related apoptosis inducing ligands, galectin-1 and DC-SIGN and production of immunosuppressive...
23 KB (2,765 words) - 17:17, 20 November 2023
Galectin-2 is a protein that in humans is encoded by the LGALS2 gene. The protein encoded by this gene is a soluble beta-galactoside binding lectin. The...
6 KB (785 words) - 22:29, 2 December 2023
Galectin-7 is a protein that in humans is encoded by the LGALS7 gene. The galectins are a family of beta-galactoside-binding proteins implicated in modulating...
5 KB (699 words) - 05:53, 3 January 2024
spina bifida. In 2019, Farmer and Aijun Wang identified exosomes and galectin 1 as key to protecting neurons and ultimately reducing the lower-limb paralysis...
7 KB (686 words) - 18:22, 11 August 2024
major classes of mammalian glycan-binding proteins (GBPs): C-type lectin, galectin, and SIGLEC immune receptors that bind carbohydrates: CD1, T cell receptor...
14 KB (1,768 words) - 00:46, 22 June 2024
targeted drugs. Following this, Shipp's research team found that serum galectin-1 levels were "significantly associated with tumor burden and additional...
6 KB (518 words) - 14:15, 26 February 2024
proteins that can deliver death signals in leukocytes (Fas ligand and galectin-1). The formation of a leukocyte infiltrate at places of inflammation is...
8 KB (786 words) - 14:19, 21 August 2023
America A publication entitled "Targeting stroma and tumor, silencing galectin-1 treats orthotopic mouse HCC" was featured in UC Davis Health News, November...
11 KB (1,247 words) - 18:11, 27 October 2024
Grabski S, Wang JL, Patterson RJ (September 2001). "Association of galectin-1 and galectin-3 with Gemin4 in complexes containing the SMN protein". Nucleic...
9 KB (1,120 words) - 02:34, 16 July 2024
Klotho causes cell-surface retention of TRPV5 channel via binding to galectin-1". Proceedings of the National Academy of Sciences of the United States...
14 KB (1,756 words) - 10:15, 6 January 2024
Molecular and Cellular Biology (2008) 4377–4385. Belanis L, et al., Galectin-1 Is a Novel Structural Component and a Major Regulator of H-Ras Nanoclusters...
35 KB (4,425 words) - 05:58, 29 December 2023
(HGF), Notch-1, sonic hedgehog (SHH), noggin, ciliary neurotrophic factor (CNTF), and a soluble carbohydrate-binding protein, Galectin-1, are reported...
19 KB (2,444 words) - 16:04, 17 June 2024
negatively selected to undergo apoptosis. The molecules like gal-3 (Galectin-3) and gal-1(Galectin-1), on the other hand, produce antagonistic effects. They inhibit...
10 KB (1,482 words) - 12:14, 4 May 2022
membrane microdomains occurs on human T cells during apoptosis induced by galectin-1". Journal of Immunology. 163 (7): 3801–11. doi:10.4049/jimmunol.163.7...
10 KB (1,221 words) - 07:18, 15 October 2024
membrane microdomains occurs on human T cells during apoptosis induced by galectin-1". J. Immunol. 163 (7): 3801–11. doi:10.4049/jimmunol.163.7.3801. PMID 10490978...
10 KB (1,283 words) - 07:14, 15 October 2024
PMID 11994467. Gauthier L, Rossi B, Roux F, Termine E, Schiff C (October 2002). "Galectin-1 is a stromal cell ligand of the pre-B cell receptor (BCR) implicated in...
7 KB (1,043 words) - 14:25, 3 December 2023
matri-cellular proteins. The up regulation of matri-cellular proteins such as galectin-1, and tenascin-C is present in the stromal tissues of pancreatic cancer...
20 KB (2,479 words) - 05:51, 15 May 2024
1016/S1097-2765(01)00244-1. PMID 11389857. Park JW, Voss PG, Grabski S, Wang JL, Patterson RJ (September 2001). "Association of galectin-1 and galectin-3 with Gemin4...
9 KB (1,126 words) - 23:02, 9 June 2024
Charcot–Leyden crystals are microscopic crystals composed of eosinophil protein galectin-10 found in people who have allergic diseases such as asthma or parasitic...
5 KB (436 words) - 04:13, 27 April 2024