Gemtuzumab ozogamicin, sold under the brand name Mylotarg, is an antibody-drug conjugate (a drug-linked monoclonal antibody) that is used to treat acute...
15 KB (1,212 words) - 14:04, 24 April 2024
called ozogamicin. Ozogamicin is N-acetyl-gamma-calicheamicin dimethylhydrazide. It includes the same linker, called "AcBut", and toxin, as gemtuzumab ozogamicin...
13 KB (1,248 words) - 01:31, 18 May 2024
a cytotoxic agent from the class of calicheamicins. Gemtuzumab ozogamicin Inotuzumab ozogamicin "マイロターグ点滴静注用5mg インタビューフォーム" [Myrotarg 5mg for intravenous...
4 KB (96 words) - 14:02, 24 April 2024
from the differentiating promyelocytes. The monoclonal antibody, gemtuzumab ozogamicin, has been used successfully as a treatment for APL, although it...
30 KB (3,230 words) - 02:57, 13 July 2024
due to their targeting properties. In 2001 Pfizer/Wyeth's drug Gemtuzumab ozogamicin (trade name: Mylotarg) was approved based on a study with a surrogate...
41 KB (4,305 words) - 05:27, 17 July 2024
arabinoside Dasatinib Daunorubicin Decitabine Etoposide Fludarabine Gemtuzumab ozogamicin Idarubicin Imatinib mesylate Interferon-α Interleukin-2 Melphalan...
1 KB (70 words) - 18:51, 14 November 2023
expression is known to be tied to TREM2. CD33 is the target of gemtuzumab ozogamicin (trade name: Mylotarg®; Pfizer/Wyeth-Ayerst Laboratories), an antibody-drug...
8 KB (889 words) - 07:57, 18 August 2023
for cancer include: Alemtuzumab Bevacizumab Cetuximab Dostarlimab Gemtuzumab ozogamicin Ipilimumab Nivolumab Ofatumumab Panitumumab Pembrolizumab Ranibizumab...
49 KB (4,964 words) - 04:02, 9 August 2024
Tositumomab), CD30 (Brentuximab), CD52 (Alemtuzumab) myeloid: CD33 (Gemtuzumab ozogamicin) Other Amivantamab Atezolizumab Avelumab Belantamab mafodotin Bermekimab...
12 KB (760 words) - 03:40, 23 July 2024
Semprex-D, an antihistamine and decongestant Inotuzumab ozogamicin and gemtuzumab ozogamicin, both through Celltech's collaboration with Wyeth. Amongst...
9 KB (811 words) - 09:16, 18 May 2024
hypercholesterolemia Refractory hypercholesterolemia 125522 Link gemtuzumab ozogamicin Mylotarg Wyeth 9/1/17 intravenous humanized, antibody-drug conjugate...
57 KB (4,072 words) - 11:12, 5 August 2024
Liver toxicity. Gatifloxacin 2006 US Increased risk of dysglycemia. Gemtuzumab ozogamicin (Mylotarg) 2010 US No improvement in clinical benefit; risk for...
46 KB (1,964 words) - 04:27, 22 July 2024
conjugates using calicheamicins as cytotoxic agents: Gemtuzumab ozogamicin Inotuzumab ozogamicin Maiese, William M; Lechevalier, Mary P; Lechevalier,...
16 KB (1,506 words) - 18:06, 10 February 2024
versus host disease Gedivumab mab human Hemagglutinin (influenza) Gemtuzumab ozogamicin Mylotarg mab humanized CD33 Y acute myelogenous leukemia Gevokizumab...
135 KB (4,054 words) - 22:35, 2 July 2024
traditional systemic approaches. The first approved drug of this type was gemtuzumab ozogamicin (Mylotarg), released by Wyeth (now Pfizer). The drug was approved...
155 KB (17,535 words) - 17:30, 29 July 2024
reduce the risk of infection or the need for blood transfusions. Gemtuzumab ozogamicin (marketed as Mylotarg), a similar drug from Pfizer that also targets...
5 KB (505 words) - 18:25, 12 August 2023
Fomivirsen and, more recently, Pfizer's (formerly Wyeth) Mylotarg (gemtuzumab ozogamicin). Examples of ADCs in phase III of development are Abbott's / Isis's...
99 KB (12,113 words) - 10:55, 22 February 2024
protein. Antibody-drug conjugates such as Brentuximab vedotin and Gemtuzumab ozogamicin are examples falling into this category. Protein-protein conjugations...
43 KB (4,688 words) - 21:02, 26 June 2024
Tositumomab), CD30 (Brentuximab), CD52 (Alemtuzumab) myeloid: CD33 (Gemtuzumab ozogamicin) Other Amivantamab Atezolizumab Avelumab Belantamab mafodotin Bermekimab...
12 KB (758 words) - 23:46, 14 March 2024
L01FG01 Bevacizumab L01FG02 Ramucirumab L01FX01 Edrecolomab L01FX02 Gemtuzumab ozogamicin L01FX03 Catumaxomab L01FX04 Ipilimumab L01FX05 Brentuximab vedotin...
12 KB (877 words) - 15:36, 25 January 2024
to gemfibrozil. gemfibrozil (INN) Gemonil (Abbott Laboratories) gemtuzumab ozogamicin (INN) Gemzar (Eli Lilly) Gen-Xene Genapax Gencept Generlac Genesa...
14 KB (644 words) - 04:49, 5 August 2024
gastroscopy – gefitinib – geldanamycin analog – GEM 231 – gemcitabine – gemtuzumab ozogamicin – gene expression profiling – gene therapy – gene transfer – gene-modified...
69 KB (5,119 words) - 11:20, 3 June 2024
retention, hypocalcaemia, osteonecrosis of the jaw and anaphylaxis. Gemtuzumab ozogamicin IV CD33 antibody that induces apoptosis of the tagged cell. Acute...
52 KB (708 words) - 00:21, 11 April 2024
Farletuzumab§ Ficlatuzumab§ Flotetuzumab§ Gemtuzumab ozogamicin Glofitamab Imgatuzumab§ Inotuzumab ozogamicin Labetuzumab§ Lifastuzumab vedotin§ Lintuzumab§...
5 KB (368 words) - 23:51, 17 July 2024
Farletuzumab§ Ficlatuzumab§ Flotetuzumab§ Gemtuzumab ozogamicin Glofitamab Imgatuzumab§ Inotuzumab ozogamicin Labetuzumab§ Lifastuzumab vedotin§ Lintuzumab§...
3 KB (129 words) - 01:04, 19 July 2023
Farletuzumab§ Ficlatuzumab§ Flotetuzumab§ Gemtuzumab ozogamicin Glofitamab Imgatuzumab§ Inotuzumab ozogamicin Labetuzumab§ Lifastuzumab vedotin§ Lintuzumab§...
4 KB (241 words) - 13:42, 14 July 2024