Globotriaosylceramide is a globoside. It is also known as CD77, Gb3, GL3, and ceramide trihexoside. It is one of the few clusters of differentiation that...
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toxin bind to a component of the cell membrane known as glycolipid globotriaosylceramide (Gb3). Binding of the subunit B to Gb3 causes induction of narrow...
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needed] The digestive tract of cattle lack the Shiga toxin receptor globotriaosylceramide, and thus, these can be asymptomatic carriers of the bacterium....
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(Ceramide-βGlc4-1βGal4-1αGal), like in the case of the most basic globoside, globotriaosylceramide (Gb3), also known as pk-antigen. Another important characteristic...
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A, encoded by GLA) due to mutation causes a glycolipid known as globotriaosylceramide (abbreviated as Gb3, GL-3, or ceramide trihexoside) to accumulate...
37 KB (3,906 words) - 03:49, 14 September 2024
In enzymology, a globotriaosylceramide 3-beta-N-acetylgalactosaminyltransferase (EC 2.4.1.79) is an enzyme that catalyzes the chemical reaction...
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for breaking down globotriaosylceramide, a fatty substance stored various types of cardiac and renal cells. When globotriaosylceramide is not properly catabolized...
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endothelial injury in locations such as the kidney by binding to globotriaosylceramide (Gb3).[citation needed] Names of the group and its subgroups include...
21 KB (2,276 words) - 02:40, 29 June 2024
corresponding defects for galactocerebrosides are: a) Ceramide trihexoside (globotriaosylceramide) accumulation – Fabry's disease. Clinical features include acroparaesthesia...
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may refer to: GB3 Championship, an open wheel motor racing series Globotriaosylceramide - It is also known as CD77, Gb3, and ceramide trihexoside Greater...
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α-GalA, which is responsible for breaking down the sphingolipid globotriaosylceramide (Gb3), among other glycolipids and glycoproteins. Some of these...
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a lack of sweat glands. Fabry disease, characterized by excess globotriaosylceramide (GL3), causes a decrease in sweat gland function due to GL3 deposits...
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symptoms seen with HUS. Shiga toxin gains entry to cells by binding to globotriaosylceramide (Gb3) which is a globoside found on cell membranes, it is found...
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include Galbeta1-4Glcbeta1-Cer alpha1,4-galactosyltransferase, globotriaosylceramide/CD77 synthase, and histo-blood group Pk UDP-galactose. This enzyme...
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do not normally produce FG but produce the precursor glycolipids globotriaosylceramide and globoside. This protein may be involved in the tropism and binding...
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Killen PD, Brady RO, Kulkarni A, and Shayman JA. Reduction of globotriaosylceramide in Fabry disease mice by substrate deprivation. J Clin Invest....
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EC 2.4.1.78: phosphopolyprenol glucosyltransferase EC 2.4.1.79: globotriaosylceramide 3-β-N-acetylgalactosaminyltransferase EC 2.4.1.80: ceramide glucosyltransferase...
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catalyzes the transfer of galactose to lactosylceramide to form globotriaosylceramide, which has been identified as the P(k) antigen of the P blood group...
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upon it, aiding transfer of galactose to lactosylceramide to form globotriaosylceramide. CDw17+antigen at the U.S. National Library of Medicine Medical...
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asymptomatic bacteriuria. PapGI adhesins bind preferentially to globotriaosylceramide (GbO3), while the isoreceptors of PapGIV are unknown. E. coli carrying...
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cDNAs. Identification of beta 3Gal-T3 as UDP-N-acetylgalactosamine:globotriaosylceramide beta 1,3-N-acetylgalactosaminyltransferase". J Biol Chem. 275 (51):...
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Three-dimensional structure of the oligosaccharide terminus of globotriaosylceramide and isoglobotriaosylceramide in solution. A rotating-frame NOE study...
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Selden RF, Brady RO. Infusion of a-galactosidase A reduces tissue globotriaosylceramide storage in patients with Fabry disease. Proc Natl Acad Sci USA 2000;...
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comprehensive line of sphingolipids, glycosphingolipids, gangliosides, globotriaosylceramides, fatty acids, and sterols. Freed, Ben (5 June 2012). "Cayman Chemical...
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same as cholera toxin. The main receptor for the shiga toxin is globotriaosylceramide or Gb3. Shiga toxin is also brought to the golgi apparatus before...
25 KB (2,916 words) - 14:03, 4 January 2024
pharmacological chaperone 1-deoxygalactonojirimycin reduces tissue globotriaosylceramide levels in a mouse model of Fabry disease. Mol. Ther. 18:23–33, 2010...
35 KB (3,726 words) - 21:03, 9 June 2024
Stephen; Lingwood, Clifford A; Branch, Donald R (2010). "A synthetic globotriaosylceramide analogue inhibits HIV-1 infection in vitro by two mechanisms". Glycobiology...
41 KB (3,724 words) - 11:10, 9 July 2024