Glucokinase (EC 2.7.1.2) is an enzyme that facilitates phosphorylation of glucose to glucose-6-phosphate. Glucokinase occurs in cells in the liver and...

The glucokinase regulatory protein (GKRP) also known as glucokinase (hexokinase 4) regulator (GCKR) is a protein produced in hepatocytes (liver cells)...

group from ATP to a substrate. Hexokinases should not be confused with glucokinase, which is a specific hexokinase found in the liver. All hexokinases are...

is converted to F1P in the liver. This negates the action of F6P on glucokinase, which ultimately favors the forward reaction. The capacity of liver...

Glucokinase regulator is a protein that in humans is encoded by the GCKR gene. This gene encodes a protein belonging to the GCKR subfamily of the SIS...

intracellular starch or glycogen. In animals, an isozyme of hexokinase called glucokinase is also used in the liver, which has a much lower affinity for glucose...

cells. Due to this, Glucokinase and glucokinase activators are the focus of treatment for those with type 2 diabetes mellitus. Glucokinase have a single allosteric...

In enzymology, an ADP-specific glucokinase (EC 2.7.1.147) also known as ADP-dependent glucokinase is an enzyme that catalyzes the chemical reaction ADP...

mutations of transcription factor genes. One form is due to mutations of the glucokinase gene. For each form of MODY, multiple specific mutations involving different...

for his contributions in diabetes research, specifically the work of Glucokinase activation as a treatment therapy for type 2 diabetes. Ramakanth Sarabu...

first enzyme in the glycolysis pathway, has a specialized form called glucokinase expressed in the liver and pancreas that has a lower affinity for glucose...

human chromosome 7 for glucokinase. Glucokinase serves as the glucose sensor for the pancreatic beta cell. Normal glucokinase triggers insulin secretion...

Catholic novelist and author GK Barry, English influencer and presenter Glucokinase, an enzyme that facilitates phosphorylation of glucose to glucose-6-phosphate...

northwestern Iranian language branch, spoken in Iran's Gilan Province Glucokinase, an enzyme that facilitates phosphorylation of glucose to glucose-6-phosphate...

for hexokinase A (brain hexokinase) to about 50 mM for hexokinase D ("glucokinase", liver hexokinase), more than a 2000-fold range. It would be impossible...

Cadisegliatin (TTP399) is a liver-selective glucokinase activator. It is being developed by VTV Therapeutics for treatment of type 2 diabetes or type...

concentration gradient through the GLUT2 transporter. Since beta cells use glucokinase to catalyze the first step of glycolysis, metabolism only occurs around...

there as a cellular glycogen. In the liver cell, it is phosphorylated by glucokinase at position 6 to form glucose 6-phosphate, which cannot leave the cell...

conventional glucokinase and phosphofructokinase, two novel sugar kinase have been discovered. These enzymes are ADP-dependent glucokinase (ADP-GK) and...

the association of insulin and SREBP-1 lead to the gene expression of glucokinase. The interaction of glucose and lipogenic gene expression is assumed...

obesity and type 2 diabetes. This includes research identifying the genes glucokinase and HNF1 risk factors for type 2 diabetes. In 2007, he was elected to...

levels. Glucose is converted into glucose 6-phosphate by the action of glucokinase or hexokinase with conversion of ATP to ADP. Glucose-6-phosphate is converted...

Globalagliatin (SY-004) is a glucokinase activator developed by Yabao Pharmaceutical Group for type 2 diabetes. Zhao, Yuqing; Xie, Lijun; Zhang, Hongwen;...

gene (SCHAD-CHI) and glucokinase (GCK-CHI). More recently, changes in hexokinase 1 (HK1), another enzyme similar to glucokinase has been identified to...

fitness, and be favoured by natural selection. An example of an isozyme is glucokinase, a variant of hexokinase which is not inhibited by glucose 6-phosphate...

catalyzed by the enzyme hexokinase in most cells, and, in higher animals, glucokinase in certain cells, most notably liver cells. One equivalent of ATP is...

Hyperinsulinism due to focal adenomatous hyperplasia Hyperinsulinism due to glucokinase deficiency Hyperinsulinism due to glutamodehydrogenase deficiency Hyperinsulinism...

enters the β-cell is phosphorylated to glucose-6-phosphate (G-6-P) by glucokinase (hexokinase IV) which is not inhibited by G-6-P in the way that the hexokinases...

and fat cells. Once within cells, glucose is rapidly phosphorylated by glucokinase in the liver and hexokinase in other tissues to form glucose-6-phosphate...

two sugar monosaccharides, glucose and galactose. Another example is Glucokinase, which is an enzyme involved in the phosphorylation of glucose to glucose-6-phosphate...