Glutathione synthetase (GSS) (EC 6.3.2.3) is the second enzyme in the glutathione (GSH) biosynthesis pathway. It catalyses the condensation of gamma-glutamylcysteine...

Glutathione synthetase deficiency (GSD) is a rare autosomal recessive metabolic disorder that prevents the production of glutathione. Glutathione helps...

in glutathione synthesis. Second, glycine is added to the C-terminal of γ-glutamylcysteine. This condensation is catalyzed by glutathione synthetase. While...

of GSH from the synthetic enzymes gamma-glutamylcysteine synthetase and glutathione synthetase, as well as the action of specific transporters to remove...

ligase (forms an isopeptide bond, which is not a peptide bond) and glutathione synthetase (forms a peptide bond). A peptide bond can be broken by hydrolysis...

the enzymes glutamate–cysteine ligase (GCL) and glutathione synthetase (GSS) to produce glutathione. Harris Ripps, Wen Shen (2012). "Review: Taurine:...

same enzymes that create GSH, namely Glutamate–cysteine ligase and glutathione synthetase. Major regulators of OPH biosynthesis are local (relative) concentrations...

Genetic significant dose German shepherd dog Global Species Database Glutathione synthetase deficiency Glycogen storage disease GSD microscopy GSD chemical...

2), previously known as γ-glutamylcysteine synthetase (GCS), is the first enzyme of the cellular glutathione (GSH) biosynthetic pathway that catalyzes...

leukotriene-C4 glutathione-lyase (leukotriene-A4-forming). Other names in common use include leukotriene C4 synthetase, LTC4 synthase, LTC4 synthetase, leukotriene...

believed mechanism for synthetase activity is that first glutathione and Mg2+-ATP bind to the enzyme in a ternary complex where glutathione becomes activated...

corresponding alcohols. GPx1 typically uses glutathione (GSH) as the reductant, but when glutathione synthetase (GSS) is, as in brain mitochondria, γ-glutamylcysteine...

defect glycolysis Glucose-6-phosphate dehydrogenase deficiency and glutathione synthetase deficiency, causing increased oxidative stress Hemoglobinopathies...

Genome survey sequence Gerstmann–Sträussler–Scheinker syndrome Glutathione synthetase Granulomatous slack skin Gudjonsson suggestibility scale Grønlands...

cysteine. This dipeptide is then condensed with glycine by glutathione synthetase to form glutathione. In chemistry, peptides are synthesized by a variety of...

Glutaricaciduria I Glutaricaciduria II Glutaryl-CoA dehydrogenase deficiency Glutathione synthetase deficiency Glyceraldehyde-3-phosphate dehydrogenase deficiency Glycine...

The compound inhibits gamma-glutamylcysteine synthetase, the enzyme required in the first step of glutathione synthesis. Buthionine sulfoximine may also...

serine) catalyzed by glutathione synthetase. Both steps of the synthesis of glutathione are ATP dependent reactions. Glutathione is maintained in the...

6.3.2.2; formerly γ-glutamylcysteine synthetase).  The production of GGC is the rate limiting step in glutathione synthesis. GGC occurs in human plasma...

element-binding protein 2 GNAS1: Gs alpha subunit (membrane G-protein) GSS: glutathione synthetase HSPA12B: encoding protein Heat shock protein family a (hsp70) member...

gluconeogenesis. D-alanine-D-alanine ligase glutathione synthetase biotin carboxylase carbamoyl phosphate synthetase ribosomal protein S6 modification enzyme...

anemia due to gamma-glutamylcysteine synthetase deficiency; 230450; GCLC Hemolytic anemia due to glutathione synthetase deficiency; 231900; GSS Hemolytic...

ligase, also known as gamma-glutamylcysteine synthetase, is the first rate limiting enzyme of glutathione synthesis. The enzyme consists of two subunits...

the sulfur. Selenocysteine is present in several enzymes (for example glutathione peroxidases, tetraiodothyronine 5′ deiodinases, thioredoxin reductases...

ligase, also known as gamma-glutamylcysteine synthetase is the first rate limiting enzyme of glutathione synthesis. The enzyme consists of two subunits...

encoded by sodA and sodB), catalases (katE and katG), glutathione synthetase (gshAB) and glutathione reductase (gor). Some bacteria have NADH-dependent peroxidases...

synthase (EC 6.3.1.8) is an enzyme that catalyzes the chemical reaction glutathione + spermidine + ATP ⇌ {\displaystyle \rightleftharpoons } glutathionylspermidine...

8-tetrahydrosarcinapterin. Li H, Xu H, Graham DE, White RH (August 2003). "Glutathione synthetase homologs encode alpha-L-glutamate ligases for methanogenic coenzyme...

\rightleftharpoons } glutathione + spermidine Thus, the two substrates of this enzyme are glutathionylspermidine and H2O, whereas its two products are glutathione and...

homoglutathione synthetase, and beta-alanine specific hGSH synthetase. Macnicol PK (1987). "Homoglutathione and glutathione synthetases of legume seedlings...