• Glycosylases (EC 3.2) are enzymes that hydrolyze glycosyl compounds. They are a type of hydrolase (EC 3). In turn, glycosylases are divided into two groups:...
    901 bytes (78 words) - 13:51, 30 December 2019
  • DNA glycosylases are a family of enzymes involved in base excision repair, classified under EC number EC 3.2.2. Base excision repair is the mechanism by...
    34 KB (4,056 words) - 12:54, 29 October 2024
  • Thumbnail for Uracil-DNA glycosylase
    Uracil-DNA glycosylase (also known as UNG or UDG) is an enzyme. Its most important function is to prevent mutagenesis by eliminating uracil from DNA molecules...
    14 KB (1,814 words) - 16:57, 27 August 2024
  • Thumbnail for DNA-3-methyladenine glycosylase
    DNA-3-methyladenine glycosylase also known as 3-alkyladenine DNA glycosylase (AAG) or N-methylpurine DNA glycosylase (MPG) is an enzyme that in humans...
    24 KB (2,620 words) - 08:29, 5 August 2024
  • Thumbnail for Base excision repair
    categories of glycosylases: monofunctional and bifunctional. Monofunctional glycosylases have only glycosylase activity, whereas bifunctional glycosylases also...
    29 KB (3,493 words) - 23:41, 26 October 2024
  • Thumbnail for Oxoguanine glycosylase
    8-Oxoguanine glycosylase, also known as OGG1, is a DNA glycosylase enzyme that, in humans, is encoded by the OGG1 gene. It is involved in base excision...
    25 KB (2,689 words) - 21:43, 28 July 2024
  • Thumbnail for Thymine-DNA glycosylase
    G/T mismatch-specific thymine DNA glycosylase is an enzyme that in humans is encoded by the TDG gene. Several bacterial proteins have strong sequence...
    12 KB (1,613 words) - 21:58, 28 July 2024
  • Double-stranded uracil-DNA glycosylase (EC 3.2.2.28, Mug, double-strand uracil-DNA glycosylase, Dug, dsUDG, double-stranded DNA specific UDG, dsDNA specific...
    2 KB (231 words) - 13:08, 4 January 2024
  • (product of cytosine deamination and not part of DNA) by uracil-DNA glycosylase, generating an abasic (AP) site. The resulting abasic site is then recognised...
    6 KB (708 words) - 13:07, 2 October 2024
  • DNA-3-methyladenine glycosylase I (EC 3.2.2.20, deoxyribonucleate 3-methyladenine glycosidase I, 3-methyladenine DNA glycosylase I, DNA-3-methyladenine...
    2 KB (196 words) - 13:54, 26 August 2023
  • pyrimidine dimer DNA-glycosylase, endonuclease V, deoxyribonucleate pyrimidine dimer glycosidase, pyrimidine dimer DNA glycosylase, T4-induced UV endonuclease...
    2 KB (165 words) - 13:47, 26 August 2023
  • Thumbnail for AlkD
    AlkD (Alkylpurine glycosylase D) is an enzyme belonging to a family of DNA glycosylases that are involved in DNA repair. It was discovered by a team of...
    6 KB (739 words) - 02:51, 1 December 2023
  • Thumbnail for Hypoxanthine
    excision repair, initiated by N-methylpurine glycosylase (MPG), also known as alkyl adenine glycosylase (Aag). Adenine Guanine Xanthine "Estimation of...
    6 KB (509 words) - 19:39, 27 August 2024
  • Thumbnail for RRNA N-glycosylase
    rRNA N-glycosylase (EC 3.2.2.22, ribosomal ribonucleate N-glycosidase, nigrin b, RNA N-glycosidase, rRNA N-glycosidase, ricin, momorcochin-S, Mirabilis...
    1 KB (142 words) - 15:45, 26 August 2023
  • DNA-deoxyinosine glycosylase (EC 3.2.2.15, DNA(hypoxanthine) glycohydrolase, deoxyribonucleic acid glycosylase, hypoxanthine-DNA glycosylase) is an enzyme...
    11 KB (1,346 words) - 08:42, 5 August 2024
  • DNA-3-methyladenine glycosylase II (EC 3.2.2.21) is an enzyme that catalyses the following chemical reaction: Hydrolysis of alkylated DNA, releasing 3-methyladenine...
    3 KB (314 words) - 13:54, 26 August 2023
  • Thumbnail for Reactive oxygen species
    single-strand-selective monofunctional uracil-DNA glycosylase 1 (SMUG1), Nei-Like DNA Glycosylase 1 (NEIL1), or methyl-CpG binding protein 4 (MBD4)....
    70 KB (8,489 words) - 08:42, 7 October 2024
  • audio codec, commonly used with the Ogg container Oxoguanine glycosylase, a DNA glycosylase enzyme Ogg (surname) Oud Gereformeerde Gemeenten, a pietistic...
    1 KB (143 words) - 00:07, 21 December 2023
  • Thumbnail for AP site
    a DNA glycosylase recognizes a damaged base and cleaves the N-glycosidic bond to release the base, leaving an AP site. A variety of glycosylases that recognize...
    8 KB (1,109 words) - 18:56, 31 May 2023
  • Thumbnail for 8-Oxo-2'-deoxyguanosine
    Increased oxidant stress inactivates temporarily the enzyme OGG1 (Oxoguanine glycosylase) at sites with 8-oxo-dG, which recruits transcription factor NFkB to...
    25 KB (2,763 words) - 21:16, 13 April 2024
  • DNA-formamidopyrimidine glycosylase (EC 3.2.2.23, Fapy-DNA glycosylase, deoxyribonucleate glycosidase, 2,6-diamino-4-hydroxy-5N-formamidopyrimidine-DNA glycosylase, 2...
    3 KB (286 words) - 13:54, 26 August 2023
  • Thumbnail for Immunoglobulin class switching
    including activation-induced (cytidine) deaminase (AID), uracil DNA glycosylase and apyrimidic/apurinic (AP)-endonucleases. AID begins the process of...
    14 KB (1,530 words) - 10:33, 15 February 2024
  • Thumbnail for Cytosine
    point mutation if not repaired by the DNA repair enzymes such as uracil glycosylase, which cleaves a uracil in DNA. Cytosine can also be methylated into...
    10 KB (906 words) - 20:09, 27 October 2024
  • Thumbnail for DNA demethylation
    ten-eleven translocation methylcytosine dioxygenase (TET) and thymine-DNA glycosylase (TDG). One particular TET enzyme, TET1, and TDG are present at high levels...
    42 KB (5,158 words) - 15:54, 31 October 2024
  • Thumbnail for Ricin
    de-purinates ribosomes, thus halting protein synthesis. RTA has rRNA N-glycosylase activity that is responsible for the cleavage of a glycosidic bond within...
    58 KB (6,571 words) - 08:21, 1 October 2024
  • Thumbnail for SMUG1
    selective monofunctional uracil DNA glycosylase is an enzyme that in humans is encoded by the SMUG1 gene. SMUG1 is a glycosylase that removes uracil from single-...
    17 KB (2,225 words) - 21:45, 28 July 2024
  • Thumbnail for Familial adenomatous polyposis
    importance in this form of cancer. MUTYH encodes DNA repair enzyme MYH glycosylase. During normal cellular activities, guanine sometimes becomes altered...
    42 KB (3,838 words) - 16:45, 27 January 2024
  • Thumbnail for DNA base flipping
    into the specificity pocket of a glycosylase which hydrolyzes the glycosidic bond and removes the base. DNA glycosylases interact with DNA, flipping bases...
    30 KB (3,431 words) - 02:56, 4 January 2024
  • Thumbnail for MUTYH
    MUTYH (mutY DNA glycosylase) is a human gene that encodes a DNA glycosylase, MUTYH glycosylase. It is involved in oxidative DNA damage repair and is part...
    23 KB (2,953 words) - 21:44, 26 October 2024
  • UDGB may refer to: Double-stranded uracil-DNA glycosylase, an enzyme Uracil-DNA glycosylase, an enzyme This disambiguation page lists articles associated...
    140 bytes (47 words) - 17:47, 30 December 2019